Purified anti-mouse IL-9 Antibody anti-IL-9

Clone: RM9A4 (See other available formats)
Regulatory Status: RUO
Other Names: Interleukin-9, P40, Mast cell growth factor (MCGF), Megakaryoblast growth factor, T cell growth factor-3 (TCGF-3)
Isotype: Rat IgG1, κ
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Product Citations: publications

Cat #	Size	Price	Save
514102	500 µg	¥43,970

Description

IL-9 is a potent, T cell-derived, T cell growth factor which can also enhance mast cell activity and IL-3- or IL-4- dependent proliferation of bone marrow-derived mast cells. IL-9 synergizes with erythropoietin to promote erythroid colony formation. IL-9 induces high affinity IgE receptor expression and granzyme A and B in murine T helper clones.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Recombinant full length mouse IL-9
Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: Upon receipt, store frozen between 2°C and 8°C.
Application: ELISA - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by ELISA assay.
Application Notes: See the protocol for Th9 polarization of mouse splenocytes.
RRID: AB_1227669 (BioLegend Cat. No. 514102)

Antigen Details

Structure: Cytokine; 30-40 kD (Mammalian)
Bioactivity: Potentiates production of IgG, IgM, and IgE by IL-4-induced B lymphocytes; regulates granzyme family proteases; enhances proliferation of bone marrow mast cells with IL-3; production of IL-6 by mast cells
Cell Sources: IL-2 activated T_H2 lymphocytes
Cell Targets: T lymphocytes, erythroid precursors
Receptors: IL-9R
Biology Area: Immunology
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Fitzgerald K, et al. Eds. 2001. The Cytokine FactsBook. Academic Press San Diego.
2. Quesniaux V, et al. 1992. Research Immunology 143:385.
3. Renauld J, et al. 1993. Adv. Immunol. 54:79.
4. Yang Y, et al. 1992. Leuk. Lymphoma 8:441.
Regulation: Upregulated by IL-1 after TCR activation, TNF-α; downregulated by antibodies to IL-2
Gene ID: 16198 View all products for this Gene ID
UniProt: View information about IL-9 on UniProt.org

Documentation

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Related Protocols

Sandwich ELISA Protocol

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Description	Clone	Applications
PE anti-mouse IL-9	RM9A4	ICFC
Purified anti-mouse IL-9	RM9A4	ELISA
APC anti-mouse IL-9	RM9A4	ICFC
Alexa Fluor® 647 anti-mouse IL-9	RM9A4	ICFC
Brilliant Violet 421™ anti-mouse IL-9	RM9A4	ICFC
PerCP/Cyanine5.5 anti-mouse IL-9	RM9A4	ICFC

Certificate of Analysis

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Go To Top Version: 1 Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

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