- Clone
- A59 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- V MR30
- Other Names
- FcαR
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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354103 | 25 tests | 104€ | ||||
354104 | 100 tests | 227€ |
CD89, also known as FcαR, is a 55-100 kD glycosylated protein. It belongs to the immunoglobulin gene family. It is expressed on granulocytes, monocytes, and macrophages but is absent on T cells. It can interact with IgA aggregates and plays an important role in IgA mediated immune responses.
Product DetailsProduct Details
- Verified Reactivity
- Human, Cynomolgus, Rhesus
- Reported Reactivity
- African Green, Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Ag8.653 myeloma cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
-
- Monteiro RC, et al. 1992. J. Immunol. 148:1764.
- Shen L. 1992. J. Leukoc. Biol. 51:373.
- Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
- Rogers KA, et al. 2004. Immunology 113:178.
- RRID
-
AB_11124742 (BioLegend Cat. No. 354103)
AB_11124742 (BioLegend Cat. No. 354104)
Antigen Details
- Structure
- Member of the immunoglobulin gene family and is a transmembrane glycoprotein, 55-100 kD
- Distribution
-
Granulocytes, neutrophils, eosinophils, monocytes, macrophages
- Function
- Interacts with IgA opsonized targets and induces immunological processes such as phagocytosis, ADCC, and release of inflammatory mediators
- Ligand/Receptor
- IgA (monomeric, dimeric, polymeric and secretory IgA)
- Cell Type
- Eosinophils, Granulocytes, Macrophages, Monocytes, Neutrophils
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
-
1. Patry C, et al. 1996. J. Immunol. 156:4442.
2. de Wit, et al. 1995. J. Immunol. 155:1203.
3. Honorio-França AC, et al. 2001. J. Leukoc. Biol. 69:289. - Gene ID
- 2204 View all products for this Gene ID
- UniProt
- View information about CD89 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD89 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human CD89 | A59 | FC |
Purified anti-human CD89 | A59 | FC |
APC anti-human CD89 | A59 | FC |
PE/Cyanine7 anti-human CD89 | A59 | FC |
PerCP/Cyanine5.5 anti-human CD89 | A59 | FC |
Biotin anti-human CD89 | A59 | FC |
FITC anti-human CD89 | A59 | FC |
APC/Fire™ 750 anti-human CD89 | A59 | FC |
Alexa Fluor® 700 anti-human CD89 | A59 | FC |
Pacific Blue™ anti-human CD89 | A59 | FC |
TotalSeq™-A1030 anti-human CD89 | A59 | PG |
TotalSeq™-C1030 anti-human CD89 | A59 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human CD89
Human peripheral blood granulocytes were stained with anti-h... -
Purified anti-human CD89
Human peripheral blood granulocytes were stained with purifi... -
APC anti-human CD89
Human peripheral blood granulocytes were stained with CD89 (... -
PE/Cyanine7 anti-human CD89
Human peripheral blood granulocytes were stained with CD89 (... -
PerCP/Cyanine5.5 anti-human CD89
Human peripheral blood granulocytes were stained with CD89 (... -
Biotin anti-human CD89
Human peripheral blood granulocytes were stained with biotin... -
FITC anti-human CD89
Human peripheral blood granulocytes were stained with anti-h... -
APC/Fire™ 750 anti-human CD89
Human peripheral blood granulocytes were stained with anti-h... -
Alexa Fluor® 700 anti-human CD89
Human peripheral blood granulocytes were stained with anti-h... -
Pacific Blue™ anti-human CD89
Human peripheral blood granulocytes were stained with anti-h... -
TotalSeq™-A1030 anti-human CD89
-
TotalSeq™-C1030 anti-human CD89
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