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PE anti-mouse Integrin αVβ8 Antibody

Pricing & Availability
Clone
S20011E (See other available formats)
Regulatory Status
RUO
Other Names
Integrin alpha V beta 8
Isotype
Rat IgG2b, λ
Ave. Rating
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Product Citations
publications
S20011E_PE_Integrin_FC_08092
Mouse integrin αVβ8 transfected Ba/F3 cells were stained with anti-mouse Integrin αVβ8 (clone S20011E) PE (filled histogram) or rat IgG2b, λ PE isotype control (open histogram).
  • S20011E_PE_Integrin_FC_08092
    Mouse integrin αVβ8 transfected Ba/F3 cells were stained with anti-mouse Integrin αVβ8 (clone S20011E) PE (filled histogram) or rat IgG2b, λ PE isotype control (open histogram).
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115407 25 µg 132€
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115408 100 µg 298€
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Description

Integrins are heterodimeric transmembrane receptors that mediate cell-cell and cell-extracellular matrix adhesion. Integrin αVβ8 is also involved in TGF-β activation, which contributes to regulatory T cell (Treg) activities.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse αVβ8 integrin-transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone S20011E does not affect the binding of clone S20011B on target cells.

Clone S20011E does not react with mouse integrin αVβ6.

RRID
AB_3662179 (BioLegend Cat. No. 115407)
AB_3662179 (BioLegend Cat. No. 115408)

Antigen Details

Structure
Integrins
Distribution

Epithelial cells

Function
Cell adhesion, TGF-β activation
Cell Type
Epithelial cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Immuno-Oncology, Immunology
Molecular Family
Adhesion Molecules
Antigen References
  1. Moyle M, et al. 1991. J Biol Chem. 266:19650-8
Gene ID
16410 View all products for this Gene ID 320910 View all products for this Gene ID
UniProt
View information about Integrin alphaVbeta8 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 08/09/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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