Alexa Fluor 647 anti-mouse CD104 Antibody anti-CD104

Pricing & Availability

Clone: 346-11A (See other available formats)
Regulatory Status: RUO
Other Names: Integrin β4, β4 integrin, TSP-1180, ITGB4
Isotype: Rat IgG2a, κ
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Product Citations: publications

Mouse lung carcinoma cell line (Line 1) was stained with CD104 (clone 346-11A) Alexa Fluor® 647 (filled histogram) or rat IgG2a, κ Alexa Fluor® 647 isotype control (open histogram).

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123607

25 µg

128€

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123608

100 µg

296€

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Description

CD104 is a 205 kD type I transmembrane glycoprotein, also known as integrin β4 chain or β4 integrin, that associates with integrin α6 (CD49f) to form the α6/β4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells (especially on proliferative basal layer epithelial cells in skin), endothelial cells, Schwann cells, certain tumor cells, and a subset of pre-T cells. The CD49f/CD104 heterodimer is an adhesion receptor for laminins (especially laminin 5) and keratin filaments, and is involved in the regulation of hemidesmosome formation and cell proliferation and activation.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Tumor-associated antigen TSP-180 from BALB/c lung carcinoma
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.

Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.

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Excitation Laser: Red Laser (633 nm)
Application Notes: Additional reported (for the relevant formats) applications include: immunohistochemical staining¹.
RRID: AB_2563511 (BioLegend Cat. No. 123607)
AB_2563511 (BioLegend Cat. No. 123608)

Antigen Details

Structure: Integrin β chain, 205 kD, forms heterodimer with integrin α6 (CD49f)
Distribution: Epithelial cells, endothelial cells, some tumor cells, pre-T cell subset
Function: Adhesion
Ligand/Receptor: Laminins, keratin filaments
Cell Type: Embryonic Stem Cells, Endothelial cells, Epithelial cells, T cells
Biology Area: Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Kennel SJ, et al. 1992. J. Cell Sciences 101:1992.
Gene ID: 192897 View all products for this Gene ID
UniProt: View information about CD104 on UniProt.org

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Related Pages & Pathways

Pathways

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Other Formats

View All CD104 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-mouse CD104	346-11A	FC,IP,ELISA
Biotin anti-mouse CD104	346-11A	FC
FITC anti-mouse CD104	346-11A	FC
Alexa Fluor® 647 anti-mouse CD104	346-11A	FC
PE anti-mouse CD104	346-11A	FC
PerCP/Cyanine5.5 anti-mouse CD104	346-11A	FC
PE/Cyanine7 anti-mouse CD104	346-11A	FC
APC anti-mouse CD104	346-11A	FC
TotalSeq™-C1028 anti-mouse CD104	346-11A	PG
TotalSeq™-B1028 anti-mouse CD104	346-11A	PG

Certificate of Analysis

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Go To Top Version: 3 Revision Date: 06-20-2018

For Research Use Only. Not for diagnostic or therapeutic use.

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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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