Pacific Blue anti-mouse CX3CR1 Antibody anti-CX3CR1

Pricing & Availability

Clone: SA011F11 (See other available formats)
Regulatory Status: RUO
Other Names: Chemokine (C-X3-C motif) receptor 1, Fractalkine receptor, GPR13, CCRL1, CMKBRL1, CMKDR1, V28
Isotype: Mouse IgG2a, κ
Ave. Rating: Submit a Review
Product Citations: publications

SA011F11_PB_CX3CR1_Antibody_1_112816 — C57BL/6 mouse splenocytes were stained with CD11b FITC and CX3CR1 (clone SA011F11) Pacific Blue (top) or mouse IgG2a, κ Pacific Blue™ isotype control (bottom).

Compare all formats See Pacific Blue™ spectral data

Cat #

Size

Price

Quantity Check Availability

Save

149037

25 µg

118€

Check Availability

Need larger quantities of this item?
Request Bulk Quote

149038

100 µg

306€

Check Availability

Need larger quantities of this item?
Request Bulk Quote

Description

CX3CR1 is a 40 kD, G-protein coupled receptor, with seven transmembrane regions. CX3CR1 is expressed by resident and alternatively activated macrophages (M2), a subset of monocytes, dendritic cells (DCs), NK cells, a subset of memory T cells, and mast cells. CX3CR1 is involved in cell recruitment during inflammation and participates in cell adhesion and extravasation from blood vessels. Its ligand is CX3CL1, also known as fractalkine or neurotactin. CX3CR1 is also a coreceptor for HIV1 and variations in this gene leads to increased susceptibility to HIV. In the brain, it is expressed by glial cells, which interact with CX3CL1 expressed by neurons.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Mouse CX3CR1-transfected cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide; may contain stabilizer.
Preparation: The antibody was purified by affinity chromatography and conjugated with Pacific Blue™ under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* Pacific Blue™ has a maximum emission of 455 nm when it is excited at 405 nm. Prior to using Pacific Blue™ conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.

Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.

View full statement regarding label licenses
Excitation Laser: Violet Laser (405 nm)
Application Notes: View more applications data for a different format of this clone in our Scientific Poster Library.
RRID: AB_2632858 (BioLegend Cat. No. 149037)
AB_2632858 (BioLegend Cat. No. 149038)

Antigen Details

Structure: G-protein coupled receptor, 7 transmembrane regions, 40 kD.
Distribution: Resident and alternatively activated macrophages (M2), subset of monocytes, dendritic cells (DCs), natural killer cells (NK), subset of memory T cells, mast cells, glial cells, and astrocytes.
Function: Involved in cell recruitment during inflammation, participates in cell adhesion and extravasation from blood vessels, coreceptor for HIV1.
Ligand/Receptor: CX3CL1 (fractalkine, neurotactin).
Cell Type: Astrocytes, Dendritic cells, Macrophages, Mast cells, Microglia, Monocytes, NK cells, T cells
Biology Area: Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family: Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Ponzetta A, et al. 2013. J. Immunol. 191:5684.
2. Jacquelin S, et al. 2013. Blood. 122:674.
3. Garcia JA, et al. 2013. J. Immunol. 191:1063.
4. Lee YS, et al. 2013. Cell. 153:413.
5. Shechter R, et al. 2013. Immunity. 38:555.
Gene ID: 13051 View all products for this Gene ID
UniProt: View information about CX3CR1 on UniProt.org

Documentation

Reviews

Review This Product

Related Protocols

Cell Surface Flow Cytometry Staining Protocol

Related Products

Description	Clone	Applications

Related Pages & Pathways

Pathways

Related FAQs

Other Formats

View All CX3CR1 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-mouse CX3CR1	SA011F11	FC
Alexa Fluor® 647 anti-mouse CX3CR1	SA011F11	FC
PE anti-mouse CX3CR1	SA011F11	FC
APC anti-mouse CX3CR1	SA011F11	FC
PerCP/Cyanine5.5 anti-mouse CX3CR1	SA011F11	FC
Brilliant Violet 421™ anti-mouse CX3CR1	SA011F11	FC
Brilliant Violet 510™ anti-mouse CX3CR1	SA011F11	FC
FITC anti-mouse CX3CR1	SA011F11	FC
Alexa Fluor® 488 anti-mouse CX3CR1	SA011F11	FC
PE/Dazzle™ 594 anti-mouse CX3CR1	SA011F11	FC
PE/Cyanine7 anti-mouse CX3CR1	SA011F11	FC
Biotin anti-mouse CX3CR1	SA011F11	FC,Cell Sep - Pos
Brilliant Violet 605™ anti-mouse CX3CR1	SA011F11	FC
Brilliant Violet 785™ anti-mouse CX3CR1	SA011F11	FC
Brilliant Violet 711™ anti-mouse CX3CR1	SA011F11	FC
Brilliant Violet 650™ anti-mouse CX3CR1	SA011F11	FC
Alexa Fluor® 700 anti-mouse CX3CR1	SA011F11	FC
APC/Fire™ 750 anti-mouse CX3CR1	SA011F11	FC
Pacific Blue™ anti-mouse CX3CR1	SA011F11	FC
TotalSeq™-A0563 anti-mouse CX3CR1	SA011F11	PG
TotalSeq™-C0563 anti-mouse CX3CR1	SA011F11	PG
TotalSeq™-B0563 anti-mouse CX3CR1	SA011F11	PG
APC/Cyanine7 anti-mouse CX3CR1 Antibody	SA011F11	FC
PE/Cyanine5 anti-mouse CX3CR1	SA011F11	FC
PE/Fire™ 700 anti-mouse CX3CR1	SA011F11	FC
APC/Fire™ 810 anti-mouse CX3CR1	SA011F11	FC
PE/Fire™ 640 anti-mouse CX3CR1	SA011F11	FC
PE/Fire™ 810 anti-mouse CX3CR1	SA011F11	FC
PerCP/Fire™ 806 anti-mouse CX3CR1	SA011F11	FC
Brilliant Violet 570™ anti-mouse CX3CR1	SA011F11	FC
PerCP/Fire™ 780 anti-mouse CX3CR1	SA011F11	FC
Spark Red™ 718 anti-mouse CX3CR1 (Flexi-Fluor™)	SA011F11	FC
Spark PLUS UV395™ anti-mouse CX3CR1	SA011F11	FC
Spark Blue™ 574 anti-mouse CX3CR1 (Flexi-Fluor™)	SA011F11	FC
Spark Blue™ 550 anti-mouse CX3CR1 (Flexi-Fluor™)	SA011F11	FC

Certificate of Analysis

Customers Also Purchased

Alexa Fluor® 700 anti-mouse/human CD11b

Clone: M1/70

Brilliant Violet 605™ anti-mouse CD11c

Clone: N418

APC/Cyanine7 anti-mouse F4/80

Clone: BM8

Brilliant Violet 510™ anti-mouse CD45

Clone: 30-F11

Go To Top Version: 2 Revision Date: 05-05-2020

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.