IMPORTANT NOTICE: Our email addresses will soon change. Learn more >>
Loading...

PE/Cyanine7 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_PECy7_042706
C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram) (gated on total cells).
  • M1slash70_PECy7_042706
    C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram) (gated on total cells).
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
101215 25 µg 70€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101216 100 µg 169€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Hatzi K, et al. 2019. Nat Immunol. 20:86. PubMed
  2. Tran NT, et al. 2019. Cell Rep. 28:3510. PubMed
  3. Lin C et al. 2019. Immunity. 50(1):137-151 . PubMed
  4. Okunuki Y, et al. 2018. Proc Natl Acad Sci U S A. 115:E6264. PubMed
  5. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  6. Parsons M, et al. 2014. J Immunol. 192:1361. PubMed
  7. Tebartz C, et al. 2015. J Immunol. 194:1100. PubMed
  8. Quispe Calla N, et al. 2016. Sci Rep. 6:37723. PubMed
  9. D'Alessandro G, et al. 2020. Eur J Immunol. 50:705. PubMed
  10. DeSouza-Vieira T, et al. 2020. Cell Rep. 33:108317. PubMed
  11. Gogoi H, et al. 2020. Front Immunol. 1.620833333. PubMed
  12. Liu K, et al. 2021. Cell Metabolism. 33(3):666-675.e4. PubMed
  13. Wang L, et al. 2021. J Nanobiotechnology. 19:56. PubMed
  14. Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
  15. Denny L, et al. 2021. Clin Transl Immunology. 10:e1234. PubMed
  16. Janbandhu V, et al. 2022. Cell Stem Cell. 29:281. PubMed
  17. Cohen K, et al. 2021. Cell Rep. 37:110026. PubMed
  18. Aimaitijiang A, et al. 2022. Genes Cells. 27:25. PubMed
  19. Schnell A, et al. 2021. Cell. 184:6281. PubMed
  20. Zhou Y, et al. 2022. Br J Pharmacol. 179:1978. PubMed
  21. Hiyoshi H, et al. 2022. Cell Host Microbe. 30:163. PubMed
  22. Wang B, et al. 2022. EMBO J. 41:e108946. PubMed
  23. Wang S, et al. 2022. Sci Adv. 8:eabn3883. PubMed
  24. Du Y, et al. 2022. J Exp Med. 219: . PubMed
  25. Pannunzio B, et al. 2022. Cells. 11: . PubMed
  26. Marié IJ, et al. 2022. Bio Protoc. 12:e4438. PubMed
  27. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  28. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  29. Liu Z, et al. 2022. Cancer Commun (Lond). 42:971. PubMed
  30. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  31. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  32. Lu Z, et al. 2022. Cell Rep. 41:111482. PubMed
  33. Mansouri S, et al. 2022. J Immunol. 209:2114. PubMed
  34. Yoo HJ, et al. 2022. Cell Rep. 41:111598. PubMed
  35. Papaxenopoulou LA, et al. 2022. iScience. 25:105522. PubMed
  36. Zhang Y, et al. 2022. Front Oncol. 12:1042250. PubMed
  37. He Y, et al. 2022. Front Immunol. 13:986202. PubMed
  38. Lee DE, et al. 2022. Nat Commun. 13:7613. PubMed
  39. Kraemer AN, et al. 2022. Front Immunol. 13:933191. PubMed
  40. Choi H, et al. 2023. J Nanobiotechnology. 21:5. PubMed
  41. Wang D, et al. 2023. J Exp Clin Cancer Res. 42:26. PubMed
  42. Leinenga G, et al. 2023. Bioeng Transl Med. 8:e10329. PubMed
  43. Wang R, et al. 2023. iScience. 26:105954. PubMed
  44. Slusarczyk P, et al. 2023. Elife. 12: . PubMed
  45. Ernst MPT, et al. 2023. Hemasphere. 7:e824. PubMed
  46. Drijvers JM, et al. 2021. Cancer Immunol Res. 9:184. PubMed
  47. Yeh CH, et al. 2022. Immunity. 55:272. PubMed
  48. Sheng YH, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:789. PubMed
  49. Banerjee K, et al. 2023. Eur J Immunol. 53:e2250161. PubMed
  50. Mela V, et al. 2023. Mol Neurobiol. 60:3044. PubMed
  51. Schönberger K, et al. 2023. Anal Chem. 95:4325. PubMed
  52. Li L, et al. 2023. iScience. 26:106095. PubMed
  53. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  54. Gupta T, et al. 2023. Front Immunol. 14:1044703. PubMed
  55. MacPherson KP, et al. 2023. Front Cell Neurosci. 17:895017. PubMed
  56. Martins Nascentes Melo L, et al. 2023. J Immunother Cancer. 11:. PubMed
  57. Pastrez PRA, et al. 2023. Cancers (Basel). 15:. PubMed
  58. Yao H, et al. 2023. Front Immunol. 14:1147674. PubMed
  59. Hernandez VG, et al. 2023. Glia. 71:1960. PubMed
  60. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  61. Lu Y, et al. 2023. J Transl Med. 21:339. PubMed
  62. Bobadilla Muñoz M, et al. 2023. Front Cell Dev Biol. 11:1128534. PubMed
  63. Doloff JC, et al. 2023. Sci Adv. 9:eade9488. PubMed
  64. Ye S, et al. 2023. Front Oncol. 13:1202750. PubMed
  65. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  66. Cheresh P, et al. 2021. Int J Mol Sci. 22:. PubMed
  67. Deng R, et al. 2022. Adv Sci (Weinh). 9:e2103343. PubMed
  68. Odom CV, et al. 2021. J Immunol. 207:1891. PubMed
  69. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  70. Li Z, et al. 2021. Immunology. 163:105. PubMed
  71. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  72. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  73. Gazit R, et al. 2014. J Exp Med. 211:1315. PubMed
  74. Giorgetti E, et al. 2020. Cell Reports. 29(6):1539-1554.e7.. PubMed
  75. Thelin MA, et al. 2017. Diabetes. 66:2220. PubMed
  76. Zhang LJ, et al. 2019. Immunity. 50:121. PubMed
  77. Abels ER et al. 2019. Cell Rep. 28(12):3105-3119 . PubMed
  78. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  79. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  80. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  81. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  82. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  83. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  84. Rodrigues M, et al. 2022. Biochem J. 479:1891. PubMed
  85. Jung MY, et al. 2022. Neurooncol Adv. 4:vdac017. PubMed
  86. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  87. Di Martile M, et al. 2020. J Immunother Cancer. 8:. PubMed
  88. Kurelac I, et al. 2019. Nat Commun. 10:903. PubMed
  89. Kobayashi Y, et al. 2018. PLoS One. 13:e0195008. PubMed
  90. Delás MJ, et al. 2019. Cell Rep. 27:719. PubMed
  91. Radovanovic I, et al. 2014. J Immunol. 193:1290. PubMed
  92. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  93. Zheng W, et al. 2021. Wellcome Open Research. 6:52. PubMed
  94. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  95. Riether C, et al. 2021. Cell Reports. 34(4):108663. PubMed
  96. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  97. Wei H, et al. 2021. Malar J. 20:89. PubMed
  98. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  99. Hickey A, et al. 2021. Front Microbiol. 12:653587. PubMed
  100. Morgan PK, et al. 2021. J Biol Chem. 297:101341. PubMed
  101. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  102. Piepke M, et al. 2021. J Neuroinflammation. 18:265. PubMed
  103. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  104. Chen T, et al. 2021. JCI Insight. 6:. PubMed
  105. Shen H, et al. 2015. Infect Immun . 83: 2694 - 2704. PubMed
  106. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
  107. Saggu G, et al. 2018. Nat Commun. 9:5058. PubMed
  108. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  109. Bowers E, et al. 2018. Nat Med. 24:95. PubMed
  110. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  111. Deslyper G, et al. 2021. Parasitology. 148:539. PubMed
  112. Akhmetzyanova ER, et al. 2019. Front Cell Neurosci. 12:507. PubMed
  113. Lubkin A et al. 2019. Cell host & microbe. 25(3):463-470 . PubMed
  114. Gibson EM, et al. 2019. Cell. 176:43:00. PubMed
  115. Juttukonda LJ, et al. 2017. Cell Host Microbe. 22:531. PubMed
  116. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  117. Somerville TD, et al. 2020. eLife. 9:e53381.. PubMed
  118. Martin R, et al. 2014. J Leukoc Biol. 96:151. PubMed
  119. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  120. Yamamoto K, et al. 2021. Cell Reports. 36(8):109576. PubMed
  121. Uroda T, et al. 2020. Nat Protoc. 15:2107. PubMed
  122. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  123. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  124. Zong L, et al. 2021. NPJ Aging Mech Dis. 7:25. PubMed
  125. Almutairi F, et al. 2021. Front Immunol. 12:772288. PubMed
  126. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  127. Royzman D, et al. 2022. Front Immunol. 13:1012647. PubMed
  128. Beauchamp EM, et al. 2021. Blood Cancer Discov. 6:. PubMed
  129. Dodagatta-Marri E, et al. 2021. Cell Rep. 36:109309. PubMed
  130. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
  131. Kulkarni NN, et al. 2021. J Biol Chem. 297:100828. PubMed
  132. Jia X, et al. 2021. Front Cell Dev Biol. 9:685522. PubMed
  133. Klopfenstein N, et al. 2021. PLoS Pathog. 17:e1009387. PubMed
  134. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  135. Vazquez S, et al. 2015. Exp Hematol. 43: 578-585. PubMed
  136. Shade K, et al. 2015. J Exp Med. 212:457. PubMed
  137. Sasaki K, et al. 2019. Nat Commun. 10:3878. PubMed
  138. Angelidis I, et al. 2019. Nat Commun. 10:963. PubMed
  139. Xu X, et al. 2021. J Nanobiotechnology. 19:376. PubMed
  140. Walker FC, et al. 2021. PLoS Pathog. 17:e1009402. PubMed
  141. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  142. Liu Y, et al. 2022. Nat Commun. 13:2665. PubMed
  143. Vasilijevic J, et al. 2017. PLoS Pathog. 13:e1006650. PubMed
  144. Meeks K, et al. 2009. J Immunol. 183:8026. PubMed
  145. Koh F, et al. 2015. Proc Natl Acad Sci U S A. 112:1734. PubMed
  146. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  147. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  148. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  149. Wang L, et al. 2021. Cancer Immunol Res. 9:348. PubMed
  150. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  151. Shin JE, et al. 2021. Heliyon. 7:e08433. PubMed
  152. Goldman E, et al. 2021. Cells. 10:. PubMed
  153. Dokoshi T, et al. 2021. J Clin Invest. 131:. PubMed
  154. Pan YC, et al. 2021. Mol Ther Oncolytics. 20:175. PubMed
  155. Aegerter H, et al. 2020. Nat Immunol. 0.975694444. PubMed
  156. Zhang S, et al. 2020. Front Immunol. 1.757638889. PubMed
  157. Kirschbaum K, et al. 2016. Proc Natl Acad Sci U S A. 113: 13227 - 13232. PubMed
  158. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  159. Snell LM, et al. 2018. Immunity. 49:678. PubMed
  160. Amo-Aparicio J, et al. 2021. Theranostics. 11:9805. PubMed
  161. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  162. Kooreman NG et al. 2018. Cell stem cell. 22(4):501-513 . PubMed
  163. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  164. Secondini C, et al. 2017. Oncoimmunology. 6:e1316437. PubMed
  165. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  166. Gomzikova MO, et al. 2020. Sci Rep. 10:10740. PubMed
  167. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  168. Okubo K, et al. 2021. Cell Reports. 35(7):109142. PubMed
  169. Gozgit JM, et al. 2021. Cancer Cell. :. PubMed
  170. Huang YL, et al. 2021. Commun Biol. 4:229. PubMed
  171. Littwitz-Salomon E, et al. 2021. Nat Commun. 12:5376. PubMed
  172. Synn CB, et al. 2022. Clin Transl Immunology. 11:e1364. PubMed
  173. Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
  174. Wang D, et al. 2021. Nat Commun. 12:2674. PubMed
  175. Jia Q, et al. 2021. Theranostics. 4699:11. PubMed
  176. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  177. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  178. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  179. Bambouskova M, et al. 2021. Cell Reports. 34(10):108756. PubMed
  180. Ringel AE, et al. 2020. Cell. 183(7):1848-1866.e26. PubMed
  181. Pérez-Girón J, et al. 2015. J Vis Exp. 100: 52803. PubMed
  182. Suresh MV, et al. 2019. JCI Insight. 4:e133103. PubMed
  183. Patel S, et al. 2019. Viruses. 0.877083333. PubMed
  184. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  185. Kumar MP, et al. 2018. Cell Rep. 25:1458. PubMed
  186. Steuerman Y et al. 2018. Cell systems. 6(6):679-691 . PubMed
  187. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  188. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  189. Marcus A et al. 2018. Immunity. 49(4):754-763 . PubMed
  190. Van Winkle JA et al. 2018. Cell host & microbe. 24(5):665-676 . PubMed
  191. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  192. Wilson DH, et al. 2020. Nat Commun. 0.767361111. PubMed
  193. Tran NT, et al. 2020. STAR Protocols. 1(1):100028. PubMed
  194. Endoh M, et al. 2020. Cell Reports. 30(6):1823-1834. PubMed
  195. Boulay A, et al. 2015. J Neurosci. 35:4427. PubMed
  196. Trefzer A, et al. 2021. Cell Reports. 34(6):108748. PubMed
  197. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  198. Li H, et al. 2020. Nature. 584:274. PubMed
  199. Sibilio A, et al. 2022. iScience. 25:103790. PubMed
  200. Dey S, et al. 2020. J Immunother Cancer. 8:. PubMed
  201. Shen M, et al. 2022. Nat Cancer. 3:60. PubMed
  202. Liu H, et al. 2022. Front Pharmacol. 13:949316. PubMed
  203. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  204. Frenis K, et al. 2021. Basic Res Cardiol. 31:116. PubMed
  205. Crouse B, et al. 2020. NPJ Vaccines. 0.277083333. PubMed
  206. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  207. Arce-Cerezo A, et al. 2015. Sci Rep. 5: 1448. PubMed
  208. Ballet R, et al. 2014. PLoS Pathog. 10:1004550. PubMed
  209. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  210. Denny JE, et al. 2019. Sci Rep. 2.786111111. PubMed
  211. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  212. Simula L et al. 2018. Cell reports. 25(11):3059-3073 . PubMed
  213. Gao C, et al. 2017. Mol Neurobiol.. 10.1007/s12035-016-0318-0. PubMed
  214. Khare P, et al. 2017. J Autoimmun. 10.1016/j.jaut.2017.09.002. PubMed
  215. Robinett RA et al. 2018. Cell systems. 7(1):41-48 . PubMed
  216. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  217. Mohamed E, et al. 2020. Immunity. 52(4):668-682.e7.. PubMed
  218. Scholz F, et al. 2015. J Immunol. 195: 2335-2342. PubMed
  219. Koelwyn GJ, et al. 2020. Nat Med. 1452:26. PubMed
  220. Kim SJ, et al. 2020. Cell Mol Immunol. 17:728. PubMed
  221. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  222. Merrell AJ, et al. 2021. Hepatology. 74:444. PubMed
  223. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  224. Yu W, et al. 2022. Nat Commun. 13:3544. PubMed
  225. Wang S, et al. 2021. Commun Biol. 22:. PubMed
  226. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  227. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  228. Bent EH, et al. 2021. Nat Commun. 12:6218. PubMed
  229. Nahrendorf W, et al. 2021. eLife. 10:00. PubMed
  230. Mansouri S, et al. 2020. Mucosal Immunol. 0.954861111. PubMed
  231. Sasaki Y, et al. 2015. PLoS One. 10: 0131176. PubMed
  232. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  233. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  234. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  235. Zhang CR, et al. 2022. Blood Cancer Discov. 3:220. PubMed
  236. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  237. Celik H, et al. 2018. Cancer Cell. 34:741. PubMed
  238. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  239. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  240. Calderon B, et al. 2015. J Exp Med. 212: 1497-1512. PubMed
  241. Richardson ET, et al. 2015. PLoS One. 10: 1371. PubMed
  242. Moro T, et al. 2016. PLoS One. 11: 0146592. PubMed
  243. Kobia FM, et al. 2020. PLoS Biol. 18:e3000850. PubMed
  244. Bordas M, et al. 2020. Int J Mol Sci. 21:00. PubMed
  245. Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
  246. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  247. Onai N, et al. 2020. Int J Mol Sci. :22. PubMed
  248. Ivan DC, et al. 2021. Front Immunol. 12:666961. PubMed
  249. Franklin DA, et al. 2020. JCI Insight. 5:. PubMed
  250. Omatsu Y, et al. 2022. Nat Commun. 13:2654. PubMed
  251. Liu W, et al. 2022. J Clin Invest. 132: . PubMed
  252. Schönberger K, et al. 2022. STAR Protoc. 3:101408. PubMed
  253. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  254. Johnson RM, et al. 2021. Front Immunol. 11:614697. PubMed
  255. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  256. Gourvest M, et al. 2021. Leukemia. . PubMed
  257. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  258. Gicheva N, et al. 2016. Biochem Biophys Res Commun. 479:1-4. PubMed
  259. Beauchamp N, et al. 2010. J Virol. 84:10191. PubMed
  260. Wang Y, et al. 2020. eLife. 9:e57438.. PubMed
  261. Yu L, et al. 2020. Nat Commun. 2.045833333. PubMed
  262. McKenzie MD, et al. 2019. Cell Stem Cell. 25:258. PubMed
  263. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  264. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  265. Cantor DJ et al. 2019. Cell reports. 26(1):108-118 . PubMed
  266. Baratin M, et al. 2017. Immunity. 47:349. PubMed
  267. Coley WD et al. 2018. F1000Research. 2018 Mar 14 [revised 2018 Jan 1] 0.5125. PubMed
  268. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  269. Sadhu S, et al. 2021. J Immunol. 207:1812. PubMed
  270. Sun L, et al. 2022. Adv Sci (Weinh). 9:e2104051. PubMed
  271. Canedo T, et al. 2021. Neuropsychopharmacology. 46:2358. PubMed
  272. Asada S, et al. 2018. Nat Commun. 9:2733. PubMed
  273. Kong XF, et al. 2018. Nat Immunol. 19:973. PubMed
  274. Rosen DA, et al. 2019. Sci Transl Med. 11:eaau5266. PubMed
  275. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  276. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  277. Süß P, et al. 2020. Cell Reports. 30(12):4082-4095. PubMed
  278. McPhee C, et al. 2013. J Immunol. 191:4581. PubMed
  279. Fujimura N, et al. 2016. Sci Rep. 5:11664. PubMed
  280. Tsunekuni K, et al. 2020. J Clin Med. 9:00. PubMed
  281. Huang WC, et al. 2020. Adv Mater. 32:e2005637. PubMed
  282. Shin M, et al. 2020. Cell Chem Biol. 314:27. PubMed
  283. Kaiser S, et al. 2020. Glia. 68:2427. PubMed
  284. Aggio-Bruce R, et al. 2020. Mol Neurobiol. . PubMed
  285. Santopaolo M, et al. 2021. Front Immunol. 609406:12. PubMed
  286. Molgora M, et al. 2020. Cell. 182:886. PubMed
  287. Shi J, et al. 2022. Front Pharmacol. 12:818326. PubMed
  288. Chavez JS, et al. 2022. Cells. 11:. PubMed
  289. Boulch M, et al. 2021. Sci Immunol. 6:. PubMed
  290. Gao P, et al. 2020. Front Immunol. 1.636111111. PubMed
  291. Chen S, et al. 2015. Cancer Res . 7: 519-531. PubMed
  292. Groppa E, et al. 2015. EMBO Mol Med. 2015; 7: 1366 - 1384. PubMed
  293. Gharib S, et al. 2014. J Leukoc Biol. 95:9. PubMed
  294. Alfaro M, et al. 2008. Proc Natl Acad Sci U S A. 105:18366. PubMed
  295. Walker JA, et al. 2020. Immunity. 51(1):104-118. PubMed
  296. Winter C, et al. 2018. Cell Metab. 28:175. PubMed
  297. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  298. Liu G, et al. 2022. Theranostics. 12:2248. PubMed
  299. Fan HH, et al. 2021. Methods Mol Biol. 2276:203. PubMed
  300. Monteiro LB, et al. 2020. MethodsX. 7:100938. PubMed
  301. Rodriguez-Tirado C, et al. 2022. Cancers (Basel). 14:. PubMed
  302. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  303. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  304. Saul S, et al. 2019. J Leukoc Biol. N/A. PubMed
  305. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
  306. Boguslawski KM, et al. 2020. Sci Adv. 6:eaax7515. PubMed
  307. Wang L, et al. 2020. J Nanobiotechnology. 18:38. PubMed
  308. Xu G, et al. 2015. Free Radic Biol Med. 87: 15-25. PubMed
  309. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  310. Akhand SS, et al. 2020. Cancer Immunol Res. 8:1542. PubMed
  311. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  312. Franklin R, et al. 2022. Nat Commun. 13:2350. PubMed
  313. Gawish R, et al. 2022. Elife. 11:. PubMed
  314. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  315. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  316. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  317. Young K, et al. 2021. Cell Stem Cell. . PubMed
  318. Lucas ED, et al. 2020. Cell Reports. 33(2):108258. PubMed
  319. Zysset D, et al. 2016. Nat Commun. 7:13151. PubMed
  320. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  321. Maas SLN, et al. 2020. J Neuroinflammation. 17:120. PubMed
  322. Qi S, et al. 2020. Theranostics. 10:1814. PubMed
  323. Zheng W, et al. 2019. Cell Rep. 29:1747. PubMed
  324. Lalor R, et al. 2019. Nutrients. 11. PubMed
  325. Cai T, et al. 2022. Front Immunol. 13:1009932. PubMed
  326. Scheyltjens I, et al. 2022. Nat Protoc. 17:2354. PubMed
  327. Zhang Y, et al. 2022. J Immunother Cancer. 10:. PubMed
  328. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
RRID
AB_312798 (BioLegend Cat. No. 101215)
AB_312798 (BioLegend Cat. No. 101216)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
PE/Fire™ 744 anti-mouse/human CD11b M1/70 FC
Spark PLUS UV395™ anti-mouse/human CD11b M1/70 FC
Spark Red™ 718 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account