Purified anti-mouse Integrin αVβ8 Antibody, Integrin αVβ8, S20011E

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Clone: S20011E (See other available formats)
Regulatory Status: RUO
Other Names: Integrin alpha V beta 8
Isotype: Rat IgG2b, λ
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Product Citations: publications

S20011E_PURE_integrin-aVB8_Antibody_1_092723 — Mouse integrin αVβ8 transfected Ba/F3 cells were stained with purified anti-mouse Integrin αVβ8 (clone S20011E) (filled histogram) or purified rat IgG2b, λ isotype control (open histogram) followed by PE goat anti-rat IgG.

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115402

100 µg

278€

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Description

Integrins are heterodimeric transmembrane receptors that mediate cell-cell and cell-extracellular matrix adhesion. Integrin αVβ8 is also involved in TGF-β activation, which contributes to regulatory T cell (Treg) activities.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Mouse αVβ8 integrin-transfected cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Clone S20011E does not affect the binding of clone S20011B on target cells.

Clone S20011E does not react with mouse integrin αVβ6.
RRID: AB_3105987 (BioLegend Cat. No. 115402)

Antigen Details

Structure: Integrins
Distribution: Epithelial cells
Function: Cell adhesion, TGF-β activation
Cell Type: Epithelial cells, Tregs
Biology Area: Cell Adhesion, Cell Biology, Immuno-Oncology, Immunology
Molecular Family: Adhesion Molecules
Antigen References: Moyle M, et al. 1991. J Biol Chem. 266:19650-8
Gene ID: 16410 View all products for this Gene ID 320910 View all products for this Gene ID
UniProt: View information about Integrin alphaVbeta8 on UniProt.org

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Other Formats

View All Integrin αVβ8 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-mouse Integrin αVβ8	S20011E	FC
FITC anti-mouse Integrin αVβ8	S20011E	FC
PE/Cyanine7 anti-mouse Integrin αVβ8	S20011E	FC
PE anti-mouse Integrin αVβ8	S20011E	FC
APC anti-mouse Integrin αVβ8	S20011E	FC

Certificate of Analysis

Go To Top Version: 1 Revision Date: 09-27-2023

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

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