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PE/Cyanine7 anti-mouse CD11c Antibody

Pricing & Availability
Clone
N418 (See other available formats)
Regulatory Status
RUO
Other Names
αX integrin, integrin αX chain, CR4, p150, ITGAX
Isotype
Armenian Hamster IgG
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Product Citations
publications
N418_A_PEslashCy7_Pos_071006
C57BL/6 mouse splenocytes stained with APC anti-mouse I-A/I-E (clone M5/114.15.2) and PE/Cyanine7 N418 (top) or PE/Cyanine7 Armenian hamster IgG isotype control (bottom)
  • N418_A_PEslashCy7_Pos_071006
    C57BL/6 mouse splenocytes stained with APC anti-mouse I-A/I-E (clone M5/114.15.2) and PE/Cyanine7 N418 (top) or PE/Cyanine7 Armenian hamster IgG isotype control (bottom)
  • N418_B_PEslashCy7_Neg_071006
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
117317 25 µg 76€
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117318 100 µg 185€
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Description

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse spleen dendritic cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for other applications.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9 (Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.

Additional Product Notes
View more applications data for this product in our Scientific Poster Library.
Application References

(PubMed link indicates BioLegend citation)
  1. Granucci F, et al. 1997. J. Immunol. 159:1794.
  2. Stokes RW, et al. 1998. J. Immunol. 160:5514.
  3. Metlay JP, et al. 1990. J. Exp. Med. 171:1753. (IHC, IP)
  4. Ma XT, et al. 2006. Cancer Research 66:1169.
  5. Chin RK, et al. 2006. J. Immunol. 177:290. (IF)
  6. Cervantes-Barragan L, et al. 2007. Blood 109:1131. (FC) PubMed
  7. Turnquist HR, et al. 2007. J. Immunol. 178:7018. (FC) PubMed
  8. Benson MJ, et al. 2007. J. Exp. Med. doi:10.1084/jem.20070719. (FC) PubMed
  9. You Y, et al. 2009. J. Immunol. 182:7343. (IF) PubMed
  10. Roland CL, et al. 2009. Mol. Cancer Res. 8:1761. (IHC, FC) PubMed
  11. Wikstrom M, et al.2006. J. Immunol. 177:913. PubMed
  12. Pericolini E, et al. 2008. J. Leukocyte Biol. 83:1286. PubMed
  13. Randall LM, et al. 2008. Infect. Immun.76:3312. PubMed
  14. Fahlen-Yrild L, et al. 2009. J. Immunol. 183:5032. PubMed
  15. Osterholzer JJ, et al. 2009. J. Immunol. 183:8044. PubMed
  16. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed
  17. Eisenach PA, et al. 2010. J Cell Sci. 123:4182. PubMed
  18. Leppin K, et al. 2014. Invest. Ophthalmol. Vis. Sci. 55:3603. PubMed
  19. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  20. Gibbins JD, et al. 2014. Blood. 124:2953. PubMed
  21. White CE, et al. 2015. J Immunol. 194:697. PubMed
  22. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  23. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  24. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Komuczki J, et al. 2019. Immunity. 50:1289. PubMed
  2. Wang X, et al. 2019. Cell Res. 29:787. PubMed
  3. Kimura S, et al. 2020. Nat Commun. 0.620833333. PubMed
  4. Al–Rashed F, et al. 2020. Sci Rep. 10:16802. PubMed
  5. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  6. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  7. Jiang Z, et al. 2021. J Clin Invest. 131: . PubMed
  8. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  9. Friess MC, et al. 2022. Cell Rep. 38:110334. PubMed
  10. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  11. Furrer R, et al. 2021. Sci Adv. 7:eabi4852. PubMed
  12. Pohlmeier L, et al. 2021. Allergy. 76:2030. PubMed
  13. Russler-Germain EV, et al. 2021. Immunity. 54:2547. PubMed
  14. Aimaitijiang A, et al. 2022. Genes Cells. 27:25. PubMed
  15. Osokine I, et al. 2022. Cell Rep. 38:110329. PubMed
  16. Cautivo KM, et al. 2022. Immunity. 55:254. PubMed
  17. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  18. Wang S, et al. 2022. Sci Adv. 8:eabn3883. PubMed
  19. Mirchandani AS, et al. 2022. Nat Immunol. 23:927. PubMed
  20. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  21. He Y, et al. 2022. Front Immunol. 13:986202. PubMed
  22. Kraemer AN, et al. 2022. Front Immunol. 13:933191. PubMed
  23. Hill AA, et al. 2023. JCI Insight. 8: . PubMed
  24. Tatsumi N, et al. 2022. STAR Protoc. 3:101845. PubMed
  25. García-García A, et al. 2023. Bioact Mater. 24:174. PubMed
  26. Cousin N, et al. 2022. Cells. 12: . PubMed
  27. Sieow JL, et al. 2023. Int J Mol Sci. 24: . PubMed
  28. Lombard-Vadnais F, et al. 2023. iScience. 26:105852. PubMed
  29. Gonçalves R, et al. 2023. iScience. 26:105972. PubMed
  30. Wei J, et al. 2022. Cancer Prev Res (Phila). 15:285. PubMed
  31. Hailemichael Y, et al. 2022. Cancer Cell. 40:509. PubMed
  32. Morris CR, et al. 2022. Mucosal Immunol. 15:977. PubMed
  33. Kedmi R, et al. 2022. Nature. 610:737. PubMed
  34. Zimmerman SM, et al. 2022. Oncogene. 41:4983. PubMed
  35. Lutz MB, et al. 2022. Eur J Immunol. . PubMed
  36. Jia DJ, et al. 2022. Gut Microbes. 14:2145843. PubMed
  37. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  38. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  39. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  40. Xu H, et al. 2023. Elife. 12:. PubMed
  41. Matsuzawa M, et al. 2023. Nat Commun. 14:1417. PubMed
  42. Palakurthi B, et al. 2023. Nat Commun. 14:2109. PubMed
  43. Shen Z, et al. 2023. iScience. 26:106572. PubMed
  44. He Y, et al. 2023. Biomolecules. 13:. PubMed
  45. Zeng S, et al. 2023. Front Oncol. 13:1171926. PubMed
  46. van Vloten JP, et al. 2022. J Immunother Cancer. 10:. PubMed
  47. Ferrere G, et al. 2021. JCI Insight. 6:. PubMed
  48. Jong RM, et al. 2022. J Immunol. 208:407. PubMed
  49. Ercoli G, et al. 2021. Front Immunol. 11:611661. PubMed
  50. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
  51. Furuta Y, et al. 2017. PLoS One. 12(2):e0172509. PubMed
  52. Kolawole A, et al. 2015. J Virol. 90: 1499-1506. PubMed
  53. Kawano H, et al. 2016. Int Immunol. 28: 489 - 501. PubMed
  54. Shin J, et al. 2016. Sci Rep. 6:23426. PubMed
  55. Fu R, et al. 2020. Sci Rep. 10:1455. PubMed
  56. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
  57. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  58. Lyons J, et al. 2018. PLoS Biol. 16:e2002417. PubMed
  59. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  60. Thwe PM et al. 2017. Cell metabolism. 26(3):558-567 . PubMed
  61. Kurelac I, et al. 2019. Nat Commun. 10:903. PubMed
  62. Quatrini L, et al. 2018. Nat Immunol. 19:954. PubMed
  63. Suzuki T, et al. 2014. J Dermatol Sci. 74:116. PubMed
  64. Clark K, et al. 2015. J Autoimmun. Available online 21 August 2015. PubMed
  65. Ndoja A, et al. 2020. Cell. 182(5):1156-1169.e12. PubMed
  66. Dong L, et al. 2021. Cancer Cell. . PubMed
  67. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  68. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  69. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  70. Boldison J, et al. 2020. Cell Mol Immunol. 17:843. PubMed
  71. Liang S, et al. 2022. Acta Pharm Sin B. 12:2494. PubMed
  72. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  73. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  74. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  75. Yu X, et al. 2021. Nature. 594:560. PubMed
  76. Pack AD, et al. 2021. Cell Reports. 36:109586. PubMed
  77. Hearnden R, et al. 2021. STAR Protocols. 2(2):100422. PubMed
  78. Yousif AS, et al. 2020. Immunity. 54(2):235-246.e5. PubMed
  79. Ku M, et al. 2016. Mol Cancer Ther. 15: 1975 - 1987. PubMed
  80. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  81. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  82. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  83. Morgado P, et al. 2014. Infect Immun . 82:4047. PubMed
  84. Ohtsuki T, et al. 2016. J Virol. 90: 300 - 307. PubMed
  85. Bazett M, Haston M 2016. Sci Rep. 6:19189. PubMed
  86. Rao S, et al. 2017. Cell. 168(3):503-516.e12. PubMed
  87. Si Y, et al. 2020. Sci Adv. 6:eaba0995. PubMed
  88. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  89. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  90. Jtte BB, et al. 2021. iScience. 24(8):102833. PubMed
  91. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  92. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  93. Papafragkos I, et al. 2022. Front Immunol. 13:889075. PubMed
  94. Khan IM, et al. 2021. Immunohorizons. 5:703. PubMed
  95. Zhang J, et al. 2022. Front Immunol. 13:931740. PubMed
  96. Zhang C, et al. 2021. Clin Transl Immunology. 10:e1310. PubMed
  97. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  98. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  99. Bagayoko S, et al. 2021. PLoS Pathog. 17:e1009927. PubMed
  100. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  101. Moreau GB, et al. 2020. Am J Trop Med Hyg. 103:1215. PubMed
  102. van Dierendonck XAMH, et al. 2020. Cell Reports. 30(6):1811-1822. PubMed
  103. Nguyen CM, et al. 2019. Diabetes. 68:1499. PubMed
  104. Britton GJ et al. 2019. Immunity. 50(1):212-224 . PubMed
  105. Lyons J, et al. 2018. Sci Signal. 11. PubMed
  106. An J,et al. 2017. Sci Rep.. 10.1038/s41598-017-13629-0. PubMed
  107. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  108. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  109. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  110. Zeng J, et al. 2019. Cell Rep. 27:549. PubMed
  111. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  112. Škrnjug I, et al. 2014. PLoS One. 9:110150. PubMed
  113. Lee M, et al. 2014. PLoS One. 9:112666. PubMed
  114. Syed A, et al. 2015. Infect Immun . 83: 3428-3437. PubMed
  115. Zhang Y, et al. 2015. PLoS Pathog. 11: e1005167. PubMed
  116. Ben-Shaanan T, et al. 2016. Nat Med. 10.1038/nm.4133. PubMed
  117. Koren N, et al. 2021. Cell Host Microbe. 29(2):197-209.e5. PubMed
  118. Wu X, et al. 2021. Elife. 10:. PubMed
  119. Crosse EI, et al. 2020. Cell Stem Cell. 27:822. PubMed
  120. Sellau J, et al. 2016. Sci Rep. 6:28058. PubMed
  121. Rosen D, et al. 2016. J Infect Dis. 213: 649 - 658. PubMed
  122. Kelsey E Sivick et al. 2018. Cell reports. 25(11):3074-3085 . PubMed
  123. Fatkhullina AR et al. 2018. Immunity. 49(5):943-957 . PubMed
  124. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  125. Si Y, et al. 2018. J Control Release. 282:120. PubMed
  126. Baudoux T, et al. 2018. Sci Rep. 4.0375. PubMed
  127. Novkovic M, et al. 2016. PLoS Biol. 14: 1002515. PubMed
  128. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  129. Souza COS, et al. 2021. iScience. 24(6):102548. PubMed
  130. Connick K, et al. 2020. J Parasit Dis. 186:44. PubMed
  131. Johnson LA, et al. 2021. Life Sci Alliance. :4. PubMed
  132. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  133. Pan Y, et al. 2022. J Clin Invest. 132:. PubMed
  134. Krollmann C, et al. 2022. STAR Protoc. 3:101309. PubMed
  135. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  136. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  137. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  138. Ercoli G, et al. 2022. Clin Transl Immunology. 11:e1366. PubMed
  139. Lewis EL, et al. 2021. Front Immunol. 12:741518. PubMed
  140. Panea C, et al. 2021. Commun Biol. 4:913. PubMed
  141. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  142. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  143. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  144. Vettorazzi S, et al. 2015. Nat Commun. 6: 7796. PubMed
  145. Christ A, et al. 2018. Cell. 172:162. PubMed
  146. Calcinotto A, et al. 2018. Nat Commun. 9:4832. PubMed
  147. Habib S, et al. 2018. Infect Immun. 86:e00019. PubMed
  148. Moon HG et al. 2018. Immunity. 49(2):275-287 . PubMed
  149. Hiebert P et al. 2018. Developmental cell. 46(2):145-161 . PubMed
  150. Tran NT, et al. 2020. STAR Protocols. 1(1):100028. PubMed
  151. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  152. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  153. Gibbins J, et al. 2014. Blood. 124:2953. PubMed
  154. Schaefer K, et al. 2014. PLoS One. 9:114824. PubMed
  155. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  156. Kim SH, et al. 2021. Cell Reports. 35(2):108995. PubMed
  157. Nikolos F, et al. 2022. Nat Commun. 13:1487. PubMed
  158. Colombo M, et al. 2022. iScience. 25:105042. PubMed
  159. Puigdelloses M, et al. 2021. J Immunother Cancer. 9:. PubMed
  160. Daneshmandi S, et al. 2021. Elife. 10:. PubMed
  161. Henrich IC, et al. 2021. Cancer Res. 81:2171. PubMed
  162. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  163. Reimer E, et al. 2020. J Cell Sci. 134:00:00. PubMed
  164. Cuenca M, et al. 2016. J Immunol. 196: 726 - 737. PubMed
  165. Hayashi K, et al. 2015. Int Immunol. 27: 435-445. PubMed
  166. Ermert D, et al. 2016. PLoS Pathog. 11: 1005043. PubMed
  167. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  168. Yang C, et al. 2019. Nanomedicine (Lond). 14:2423. PubMed
  169. Janela B, et al. 2019. Immunity. 50:1069. PubMed
  170. Colliou N, et al. 2015. Toxins. 7: 3805 - 3817. PubMed
  171. Shepardson K, et al. 2016. MBio. 7: e00506-16. PubMed
  172. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  173. Lan H, et al. 2020. Int Immunol. 559:32. PubMed
  174. Taddio MF, et al. 2021. Mol Imaging Biol. 23:196. PubMed
  175. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  176. Yang X, et al. 2022. Front Immunol. 13:856230. PubMed
  177. Ghorbani S, et al. 2022. Nat Commun. 13:2445. PubMed
  178. Clement CC, et al. 2021. Immunity. 54:721. PubMed
  179. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  180. Morikawa M, et al. 2016. PLoS One. 11:e0163607. PubMed
  181. Kim M, et al. 2018. Immunity. 49:151. PubMed
  182. Lu Y, et al. 2020. Immunity. 52:782. PubMed
  183. Dahlgren MW et al. 2019. Immunity. 50(3):707-722 . PubMed
  184. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  185. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  186. Zwick M, et al. 2019. Front Immunol. 10:222. PubMed
  187. Chan WY, et al. 2019. Infect Immun. 87:. PubMed
  188. Andersen TK, et al. 2019. NPJ Vaccines. 4:9. PubMed
  189. Lai SM et al. 2018. Cell reports. 25(11):3099-3109 . PubMed
  190. Urata S, et al. 2018. PLoS Pathog. 14:e1007172. PubMed
  191. Zhao Y, et al. 2020. Immunity. 51(6):1059-1073.e9.. PubMed
  192. Hennion-Tscheltzoff O, et al. 2013. Blood. 121:4684. PubMed
  193. Škrnjug I, et al. 2014. PLoS One. 9:95728. PubMed
  194. Velázquez F, et al. 2016. J Immunol. 196: 1305 - 1316. PubMed
  195. Ghosh D, et al. 2016. J Immunol. 197: 1788 - 1800. PubMed
  196. Yasuda T, et al. 2016. PLoS One. 11:e0167952. PubMed
  197. Kumari P, et al. 2021. Cell Reports. 35(3):109012. PubMed
  198. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  199. Li E, et al. 2021. Front Immunol. 12:667177. PubMed
  200. He S, et al. 2021. Front Pharmacol. 12:743837. PubMed
  201. Wang L, et al. 2021. Sci Adv. 7:eabj4796. PubMed
  202. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  203. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  204. Harb H, et al. 2020. Nat Immunol. 1359:21. PubMed
  205. Niven J, et al. 2019. Cell Rep. 28:21. PubMed
  206. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  207. Porrello A, et al. 2018. Nat Commun. 9:1988. PubMed
  208. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  209. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  210. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  211. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  212. Di Pilato M, et al. 2021. Cell. 184(17):4512-4530.e22. PubMed
  213. Chung S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. L921:318. PubMed
  214. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  215. Donlan AN, et al. 2021. JCI Insight. 6: . PubMed
  216. Okreglicka K, et al. 2021. J Exp Med. 218:. PubMed
  217. Stotesbury C, et al. 2020. Aging Cell. 19:e13170. PubMed
  218. Teng F, et al. 2021. Cell Rep. 37:110051. PubMed
  219. Ceglia V, et al. 2021. J Immunol. 207:2060. PubMed
  220. Bahmani B, et al. 2021. Nat Commun. 12:1999. PubMed
  221. Fite BZ, et al. 2021. Sci Rep. 11:927. PubMed
  222. Lee HN, et al. 2022. JCI Insight. 7:. PubMed
  223. Verma M, et al. 2021. J Exp Med. 218:. PubMed
  224. Kim J, et al. 2020. Adv Funct Mater. 30:. PubMed
  225. Lee GR, et al. 2021. JCI Insight. 6:. PubMed
  226. Van Nuffel E, et al. 2020. EMBO Rep. 21:e49237. PubMed
  227. Liu SS, et al. 2021. Immunity. :. PubMed
  228. Xu C, et al. 2021. Cell Reports. 35(11):109235. PubMed
  229. Hildreth AD, et al. 2020. STAR Protoc. 1:100113. PubMed
  230. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  231. Wan X, Thomas J, Unanue E 2016. J Exp Med. 213: 967 - 978. PubMed
  232. Yu H, et al. 2015. PLoS One. 10: 0143001. PubMed
  233. Jin J, et al. 2020. Cell Reports. 30(12):4124-4136. PubMed
  234. Schuh E, et al. 2017. J Immunol. 198:3081. PubMed
  235. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  236. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  237. Albaghdadi AJH, et al. 2019. Sci Rep. 9:6528. PubMed
  238. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  239. Crowe J, et al. 2020. PLoS Pathog. 16:e1008391. PubMed
  240. Saleh R, et al. 2018. J Immunol. 201:2042. PubMed
  241. Doo DW, et al. 2020. Ther Adv Med Oncol. 12:1758835920913798. PubMed
  242. Stack G, et al. 2015. PLoS Pathog. 11:1004641. PubMed
  243. Tran S, et al. 2020. Immunity. 53(3):627-640.e5. PubMed
  244. Goc J, et al. 2021. Cell. 184:5015. PubMed
  245. Schäfer AL, et al. 2021. Front Immunol. 12:696810. PubMed
  246. Hsu HP, et al. 2021. J Biol Chem. 296:100419. PubMed
  247. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  248. Dietschmann A, et al. 2020. Eur J Immunol. 50:1044. PubMed
  249. Zhang Y, et al. 2022. J Immunother Cancer. 10:. PubMed
  250. Lee S, et al. 2021. Autophagy. 18:1062. PubMed
  251. Amend A, et al. 2021. Int J Mol Sci. 22:. PubMed
  252. Wirasinha RC, et al. 2021. J Exp Med. 218: . PubMed
  253. Dai B, et al. 2021. Cell Reports Medicine. 2(8):100381. PubMed
  254. Trivedi S, et al. 2020. Elife. 9:00. PubMed
  255. Hayashi K, et al. 2020. Nat Commun. 4.832638889. PubMed
  256. Fontana C, et al. 2016. J Biol Chem. 291: 7727-7741. PubMed
  257. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
  258. Thomson CA, et al. 2018. J Immunol. 201:215. PubMed
  259. Chen S, et al. 2018. Nat Commun. 9:5298. PubMed
RRID
AB_493568 (BioLegend Cat. No. 117317)
AB_493568 (BioLegend Cat. No. 117318)

Antigen Details

Structure
Integrin α-chain, associates with integrin β2 (CD18), 150 kD
Distribution

Dendritic cells, NK cells, intestinal intraepithelial lymphocytes (IEL), some activated T cells

Function
Cellular adhesion
Ligand/Receptor
iC3b, fibrinogen
Cell Type
Dendritic cells, Epithelial cells, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen Facts Book Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lopez-Rodriguez C, et al. 1996. J. Immunol. 156:3780.

Gene ID
16411 View all products for this Gene ID
UniProt
View information about CD11c on UniProt.org

Other Formats

View All CD11c Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD11c N418 FC
Biotin anti-mouse CD11c N418 FC,IHC-F
FITC anti-mouse CD11c N418 FC
PE anti-mouse CD11c N418 FC
Purified anti-mouse CD11c N418 FC,CyTOF®,IP,IHC
Alexa Fluor® 488 anti-mouse CD11c N418 FC
Alexa Fluor® 647 anti-mouse CD11c N418 FC,IHC,ICC,3D IHC
PE/Cyanine5 anti-mouse CD11c N418 FC
PE/Cyanine7 anti-mouse CD11c N418 FC
Brilliant Violet 605™ anti-mouse CD11c N418 FC
Alexa Fluor® 700 anti-mouse CD11c N418 FC
Pacific Blue™ anti-mouse CD11c N418 FC
APC/Cyanine7 anti-mouse CD11c N418 FC
PerCP/Cyanine5.5 anti-mouse CD11c N418 FC
PerCP anti-mouse CD11c N418 FC
Brilliant Violet 421™ anti-mouse CD11c N418 FC,IHC
Brilliant Violet 570™ anti-mouse CD11c N418 FC
Brilliant Violet 785™ anti-mouse CD11c N418 FC
Brilliant Violet 510™ anti-mouse CD11c N418 FC
Brilliant Violet 650™ anti-mouse CD11c N418 FC
Purified anti-mouse CD11c (Maxpar® Ready) N418 FC,CyTOF®
Alexa Fluor® 594 anti-mouse CD11c N418 IHC-F,3D IHC
PE/Dazzle™ 594 anti-mouse CD11c N418 FC
Brilliant Violet 711™ anti-mouse CD11c N418 FC
APC/Fire™ 750 anti-mouse CD11c N418 FC
TotalSeq™-A0106 anti-mouse CD11c N418 PG
Brilliant Violet 750™ anti-mouse CD11c N418 FC
TotalSeq™-B0106 anti-mouse CD11c N418 PG
TotalSeq™-C0106 anti-mouse CD11c N418 PG
KIRAVIA Blue 520™ anti-mouse CD11c N418 FC
Spark Blue™ 550 anti-mouse CD11c N418 FC
Spark NIR™ 685 anti-mouse CD11c N418 FC
Spark UV™ 387 anti-mouse CD11c N418 FC
Spark Red™ 718 anti-mouse CD11c N418 FC
Spark Blue™ 515 anti-mouse CD11c N418 FC
PerCP/Fire™ 806 anti-mouse CD11c N418 FC
Spark PLUS UV395™ anti-mouse CD11c N418 FC
Spark Blue™ 574 anti-mouse CD11c (Flexi-Fluor™) N418 FC
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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