Purified anti-human CD48 Antibody anti-CD48

Pricing & Availability

Clone: BJ40 (See other available formats)
Regulatory Status: RUO
Other Names: Blast-1, SLAMF2, HuLy-m3
Isotype: Mouse IgG1, κ
Ave. Rating: Submit a Review
Product Citations: publications

Human peripheral blood lymphocytes stained with purified BJ40, followed by anti-mouse IgG FITC

Compare all formats

Cat #

Size

Price

Quantity Check Availability

Save

336702

100 µg

85€

Check Availability

Need larger quantities of this item?
Request Bulk Quote

Description

CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Human
Reported Reactivity: African Green, Baboon, Cynomolgus, Rhesus
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
IP - Reported in the literature, not verified in house
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, it is recommended to use at ≤ 2.0 µg per 10⁶ cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Additional reported applications (for the relevant formats) include: immunoprecipitation.
RRID: AB_1227561 (BioLegend Cat. No. 336702)

Antigen Details

Structure: CD2 family, contains 2 IgSF domains, GPI-membrane anchored, 40-47 kD
Distribution: Widely expressed on hematopoietic cells except granulocytes, platelets, and erythrocytes. Increased on T and B cells after activation
Function: Contributes to T cell antigen recognition
Ligand/Receptor: CD2
Cell Targets: Lck, Fyn interact with cytoplasmic domain
Cell Type: B cells
Biology Area: Immunology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: Fisher RC and Thorley-Lawson DA. 1991. Mol. Cell. Biol. 11:1614.

Korinek V, et al. 1991. Immunogenetics 33:108.

Leukocyte Typing IV. Knapp W, et al. (Eds) Oxford University Press (1989)

Leukocyte Typing V. Schlossman S, et al. (Eds) Oxford University Press (1995)
Gene ID: 962 View all products for this Gene ID
UniProt: View information about CD48 on UniProt.org

Documentation

Reviews

Review This Product

Related Protocols

Cell Surface Flow Cytometry Staining Protocol

Related Products

Description	Clone	Applications

Related Pages & Pathways

Pathways

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD48 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-human CD48	BJ40	FC,IP
FITC anti-human CD48	BJ40	FC
PE anti-human CD48	BJ40	FC
TotalSeq™-A0029 anti-human CD48	BJ40	PG
TotalSeq™-C0029 anti-human CD48	BJ40	PG
PerCP/Cyanine5.5 anti-human CD48	BJ40	FC
APC anti-human CD48	BJ40	FC
PE/Cyanine7 anti-human CD48	BJ40	FC
TotalSeq™-B0029 anti-human CD48	BJ40	PG
TotalSeq™-D0029 anti-human CD48	BJ40	PG

Certificate of Analysis

Customers Also Purchased

Purified anti-human CD162

Clone: KPL-1

Purified anti-human CD43

Clone: CD43-10G7

Purified anti-human CD84

Clone: CD84.1.21

Ultra-LEAF™ Purified anti-human CD229 (Ly-9)

Clone: HLy-9.1.25

Go To Top Version: 2 Revision Date: 08.18.2022

For Research Use Only. Not for diagnostic or therapeutic use.

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.