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- Clone
- 58XB4 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Integrin β4, β4 integrin, TSP-1180, ITGB4
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human colon carcinoma cell line (HT29) stained with purified 58XB4, followed by anti-mouse IgG FITC
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 327802 | 100 µg | £81 | ||||
CD104 is a 205 kD type I transmembrane glycoprotein, known as integrin β4 chain or β4 integrin, that associates with integrin α6 (CD49f) forms α6/β4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells (especially on the proliferative basal layer epithelial cells in skin), endothelial cells, Schwann cells, certain tumor cells and a subset of pre-T cells. CD49f/CD104 is an adhesion receptor for laminins (especially laminin 5) and keratin filaments and is involved in the regulation of hemidesmosome formation and of cell proliferation and activation.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
-
AB_893212 (BioLegend Cat. No. 327802)
Antigen Details
- Structure
- Integrin β chain, 205 kD, forms heterodimer with integrin α6 (CD49f)
- Distribution
- Epithelial cells, endothelial cells, some tumor cells, pre-T cell subset
- Function
- Adhesion
- Ligand/Receptor
- Laminins, keratin filaments
- Cell Type
- Epithelial cells, Endothelial cells, T cells, Embryonic Stem Cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
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1. Kippenberger S, et al. 2004. J. Invest. Dermatol. 123:444.
2. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication - Gene ID
- 3691 View all products for this Gene ID
- UniProt
- View information about CD104 on UniProt.org
Related FAQs
Other Formats
View All CD104 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD104 | 58XB4 | FC |
| FITC anti-human CD104 | 58XB4 | FC |
| PE anti-human CD104 | 58XB4 | FC |
| TotalSeq™-A1029 anti-human CD104 | 58XB4 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD104
Human colon carcinoma cell line (HT29) stained with purified... -
FITC anti-human CD104
Human colon carcinoma cell line HT29 stained with 58XB4 FITC -
PE anti-human CD104
Human colon carcinoma cell line HT29 stained with 58XB4 PE -
TotalSeq™-A1029 anti-human CD104
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