APC/Fire™ 750 anti-human CD14, CD14, M5E2

Pricing & Availability

Analyte Specific Reagent. Analytical and performance characteristics are not established.

Clone: M5E2
Workshop: III 329
Other Names: LPS receptor
Isotype: Mouse IgG2a, κ

M5E2_APCFire750_ASR_CD14_Antibody_091521 — Typical results from human peripheral blood monocytes stained either with M5E2 APC/Fire™ 750 used at 5 uL/test (filled histogram) or with an isotype control (open histogram).

Compare all formats See APC/Fire™ 750 spectral data

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982512

500 µL

$376

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Description

CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.

Product Details

Technical data sheet

Product Details

Reactivity: Human
Formulation: Phosphate-buffered solution, pH7.2, containing True-Stain Monocyte Blocker™, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.
Preparation: The antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
Concentration: 400 µg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: Suggested for Flow Cytometry

Antigen Details

Antigen References: 1. Stocks S, et al. 1990. Biochem. J. 268:275.
2. Wright S, et al. 1990. Science 249:1434.

Documentation

Certificate of Analysis

Go To Top Version: 2 Revision Date: 11/06/2024

Analyte Specific Reagent. Analytical and performance characteristics are not established.

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