Loading...

FITC anti-mouse F4/80 Antibody

Pricing & Availability
Clone
BM8 (See other available formats)
Regulatory Status
RUO
Other Names
EMR1, Ly71
Isotype
Rat IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
BM8_FITC_090707
Thioglycolate-elicited Balb/c mouse peritoneal macrophages stained with BM8 FITC
  • BM8_FITC_090707
    Thioglycolate-elicited Balb/c mouse peritoneal macrophages stained with BM8 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
123107 50 µg $65
Check Availability


Need larger quantities of this item?
Request Bulk Quote
123108 500 µg $185
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

F4/80, also known as EMR1 or Ly71, is a 160 kD glycoprotein of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80 has been widely used as a murine macrophage marker. It is expressed on a majority of tissue macrophages, including macrophages in the lung, gut, peritoneal cavity, thymus, and red pulp of the spleen, Kupffer cells, Langerhans cells, microglia, and certain dendritic cells. It is not expressed on macrophages located in the T cell areas of the spleen, lymph node, or Peyer's patch. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for the induction of CD8+ T cells-mediated peripheral tolerance.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Murine macrophages
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections1,2 and formalin-fixed paraffin-embedded sections6,7, Western blotting, and spatial biology (IBEX)12,13.

Application References

(PubMed link indicates BioLegend citation)
  1. Schaller E, et al. 2002. Mol. Cell. Biol. 22:8035. (IHC)
  2. Stevceva L, et al. 2001. BMC Clin Pathol. 1:3. (IHC)
  3. Kobayashi M, et al.2008. J. Leukoc. Biol. 83:1354. PubMed
  4. Poeckel D, et al. 2009. J. Biol Chem. 284:21077. PubMed
  5. Glass AM, et al. 2013. J. Immunol. 190:4830. PubMed
  6. Koehm S, et al. 2007. J. Allergy Clin. Immunol. 120:570. (IHC)
  7. Rankin AL, et al. 2010. J. Immunol. 184:1526. (IHC)
  8. Sasi SP, et al. 2014. J Biol Chem. 289:14178. PubMed
  9. Thakus VS, et al. 2014. Toxicol Lett. 230:322. PubMed
  10. Watson NB, et al. 2015. J Immunol. 194:2796. PubMed
  11. Hirakawa H, et al. 2015. PLoS One. 10:119360. PubMed
  12. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  13. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Liu J, et al. 2019. Immunity. 50:600. PubMed
  2. Xiong Y, et al. 2020. J Nanobiotechnology. 18:66. PubMed
  3. Wang L, et al. 2008. Cancer Res. 68:5639. PubMed
  4. Jiang L, et al. 2013. Mol Immunol. 54:14. PubMed
  5. Liu K, et al. 2021. Cell Metabolism. 33(3):666-675.e4. PubMed
  6. Jiang Z, et al. 2021. J Clin Invest. 131: . PubMed
  7. Vasanthakumar A, et al. 2020. Nature. 579:581. PubMed
  8. Liang J, et al. 2021. Cancer Manag Res. 13:6977. PubMed
  9. Li F, et al. 2022. Mediators Inflamm. 2022:5782922. PubMed
  10. Wang HH, et al. 2022. J Biomed Sci. 29:36. PubMed
  11. Denny L, et al. 2021. Clin Transl Immunology. 10:e1234. PubMed
  12. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  13. Motyka NI, et al. 2022. Infect Immun. 90:e0063721. PubMed
  14. Tan YY, et al. 2022. Bio Protoc. 12:e4307. PubMed
  15. Yang Y, et al. 2022. FEBS J. 289:5279. PubMed
  16. Corral D, et al. 2022. Cell Rep. 39:110715. PubMed
  17. Wang S, et al. 2022. Sci Adv. 8:eabn3883. PubMed
  18. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  19. Poh AR, et al. 2022. Sci Adv. 8:eabl7882. PubMed
  20. Piñeros AR, et al. 2022. Cell Rep. 39:111011. PubMed
  21. Li Y, et al. 2023. Bioact Mater. 20:548. PubMed
  22. Poh AR, et al. 2022. Cell Rep. 41:111479. PubMed
  23. Xu S, et al. 2022. EBioMedicine. 86:104312. PubMed
  24. Shang T, et al. 2022. Front Pharmacol. 13:1054176. PubMed
  25. Kraemer AN, et al. 2022. Front Immunol. 13:933191. PubMed
  26. Choi H, et al. 2023. J Nanobiotechnology. 21:5. PubMed
  27. Peng Y, et al. 2023. Respir Res. 24:33. PubMed
  28. Zhong W, et al. 2023. Nat Commun. 14:491. PubMed
  29. Slusarczyk P, et al. 2023. Elife. 12: . PubMed
  30. Sacirbegovic F 2023. Immunity. N/A. PubMed
  31. Li XF, et al. 2023. J Exp Med. 220: . PubMed
  32. Wang L, et al. 2023. Oxid Med Cell Longev. 2023:6480848. PubMed
  33. Wight AE, et al. 2022. Proc Natl Acad Sci U S A. 119:e2200757119. PubMed
  34. Cacialli P, et al. 2022. EMBO J. 41:e108536. PubMed
  35. Glorieux C, et al. 2022. J Adv Res. 40:109. PubMed
  36. Hamdi L, et al. 2022. Ann Clin Transl Neurol. 9:1792. PubMed
  37. Veazey JM, et al. 2023. Immunol Cell Biol. 101:130. PubMed
  38. Suzuki Y, et al. 2023. Front Immunol. 14:1089905. PubMed
  39. Schwarz N, et al. 2023. FASEB J. 37:e22846. PubMed
  40. Vanneste D, et al. 2023. Nat Immunol. 24:827. PubMed
  41. Saha S, et al. 2023. Sci Rep. 13:4609. PubMed
  42. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  43. Cui B, et al. 2023. Int Immunopharmacol. 120:110240. PubMed
  44. Zheng M, et al. 2016. Sci Rep. 6:28729. PubMed
  45. Marcil A, et al. 2008. Infect Immun. 76:4345. PubMed
  46. Kimura H, et al. 2017. J Immunol. 10.4049/jimmunol.1601798. PubMed
  47. Chen Y, et al. 2018. EBioMedicine. 32:31. PubMed
  48. Zhang Y, et al. 2018. Sci Rep. 8:5994. PubMed
  49. Barry KC, et al. 2018. Nat Med. 24:1178. PubMed
  50. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  51. Hsu SPC, et al. 2020. J Neurooncol. 146:417. PubMed
  52. Morgan PK, et al. 2021. J Biol Chem. 297:101341. PubMed
  53. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  54. Zhang L, et al. 2022. Acta Pharm Sin B. 12:3427. PubMed
  55. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  56. Chauhan A, et al. 2020. Nat Commun. 11:1939. PubMed
  57. Rogic A, et al. 2021. Nat Commun. 12:6889. PubMed
  58. Gu T, et al. 2021. Front Immunol. 11:621441. PubMed
  59. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  60. Mouton AJ, et al. 2018. Basic Res Cardiol. 113:26:00. PubMed
  61. Lee Y, et al. 2017. PLoS One.. 10.1371/journal.pone.0183028. PubMed
  62. Stubelius A, et al. 2017. Immunobiology. 10.1016/j.imbio.2017.05.007. PubMed
  63. Qiu X, et al. 2019. Theranostics. 9:2618. PubMed
  64. Brunner JS, et al. 2020. Nat Commun. 0.757638889. PubMed
  65. Ohtsuki T, et al. 2016. J Virol. 90: 300 - 307. PubMed
  66. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  67. Alvarez M, et al. 2020. Cancers (Basel). 12:. PubMed
  68. Shi S, et al. 2020. Clin Cancer Res. 26:5990. PubMed
  69. Wang Y, et al. 2020. J Immunol. 205:2905. PubMed
  70. Zhou HF, et al. 2022. Front Pharmacol. 13:778755. PubMed
  71. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  72. Royzman D, et al. 2022. Front Immunol. 13:1012647. PubMed
  73. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  74. Kedage V, et al. 2022. MAbs. 14:2040083. PubMed
  75. Xu X, et al. 2021. J Nanobiotechnology. 19:376. PubMed
  76. Ma YV, et al. 2021. MAbs. 13:2003281. PubMed
  77. Dichtl S, et al. 2021. Sci Adv. 7: . PubMed
  78. Klopfenstein N, et al. 2021. PLoS Pathog. 17:e1009387. PubMed
  79. Ostendorf BN, et al. 2020. Nat Med. 26:1048. PubMed
  80. An YA et al. 2017. eLife. 6 pii: e24071. PubMed
  81. Nakazeki F, et al. 2018. Sci Rep. 8:8553. PubMed
  82. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  83. Zhang S, et al. 2019. Mol Med Rep. 19:5377. PubMed
  84. Dan H, et al. 2020. Mol Oncol. 14:795. PubMed
  85. García-Bonilla M, et al. 2020. Stem Cell Res Ther. 11:121. PubMed
  86. Niss K, et al. 2020. Cell Reports. 31(11):107763. PubMed
  87. Xiao Z, et al. 2015. Cancer Lett. 360:302. PubMed
  88. Velázquez K, et al. 2016. Am J Physiol Gastrointest Liver Physiol. 311: G699 - G712. PubMed
  89. Ratitong B, et al. 2021. Cell Reports. 35(7):109139. PubMed
  90. Wang F, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:257. PubMed
  91. Xiao P, et al. 2021. JCI Insight. 6:. PubMed
  92. Zheng Y, et al. 2022. Front Pharmacol. 12:816032. PubMed
  93. Jing L, et al. 2022. Front Immunol. 13:864995. PubMed
  94. Zhang X, et al. 2021. Front Immunol. 12:680068. PubMed
  95. Zhang Y, et al. 2022. Nat Commun. 13:4553. PubMed
  96. Geng T, et al. 2022. Methods Mol Biol. 2585:71. PubMed
  97. Yu H, et al. 2022. J Orthop Surg Res. 17:232. PubMed
  98. Feng T, et al. 2022. Nat Commun. 13:5208. PubMed
  99. Gu Y, et al. 2021. Cell Res. Online ahead of print. PubMed
  100. Kornstädt L, et al. 2021. Front Immunol. 11:607048. PubMed
  101. Zhao X, et al. 2014. J Biol Chem. 289:30052. PubMed
  102. Suo J, et al. 2014. J Leukoc Biol. 96:133. PubMed
  103. Bignami F, et al. 2017. Acta Ophthalmol. 95:e641. PubMed
  104. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  105. Wu W, et al. 2018. J Am Soc Nephrol. 29:168. PubMed
  106. Niemann J, et al. 2019. Nat Commun. 10:3236. PubMed
  107. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  108. Odkhuu E, et al. 2014. Innate Immunity. 21:194. PubMed
  109. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  110. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  111. Omori S, et al. 2021. Cell Reports. 34(6):108734. PubMed
  112. DeVito NC, et al. 2021. Cell Reports. 35(5):109071. PubMed
  113. Duan RN, et al. 2021. J Neuroinflammation. 18:145. PubMed
  114. Wang J, et al. 2021. Nat Commun. 12:6198. PubMed
  115. Wang Y, et al. 2021. EMBO J. 40:e105543. PubMed
  116. Wang H, et al. 2022. J Nanobiotechnology. 20:445. PubMed
  117. Wang Y, et al. 2022. Cell Death Dis. 13:748. PubMed
  118. Wu Y, et al. 2021. PLoS Negl Trop Dis. 15:e0010050. PubMed
  119. Lewis EL, et al. 2021. Front Immunol. 12:741518. PubMed
  120. Cai C, et al. 2021. Sci Rep. 11:13386. PubMed
  121. Barsoumian HB, et al. 2020. J Immunother Cancer. 8:00. PubMed
  122. Vettorazzi S, et al. 2015. Nat Commun. 6: 7796. PubMed
  123. Miki Y, et al. 2013. J Exp Med. 210:1217. PubMed
  124. Linde N, et al. 2012. PLoS One. 7:e40058. PubMed
  125. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  126. Wan X, et al. 2018. Nature. 560:107. PubMed
  127. Niknam S, et al. 2018. Clin Cancer Res. 24:5735. PubMed
  128. Tavazoie MF, et al. 2018. Cell. 172:825. PubMed
  129. Yu Y, et al. 2018. Mol Med Rep. 17:8212. PubMed
  130. Irie Y, et al. 2017. J Neuroimmune Pharmacol. 10.1007/s11481-017-9757-2. PubMed
  131. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  132. Van Winkle JA et al. 2018. Cell host & microbe. 24(5):665-676 . PubMed
  133. Martínez‐López M et al. 2019. Immunity. 50(2):446-461 . PubMed
  134. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  135. Kasahara D, et al. 2012. J Immunol. 188:4558. PubMed
  136. Artz A, Butz S, Vestweber D 2016. Am J Physiol Renal Physiol. 311: F176 - F181. PubMed
  137. Abe M, et al. 2020. Clin Exp Immunol. 303:199. PubMed
  138. Zhu Y, et al. 2021. EMBO J. 40:e105320. PubMed
  139. Machácek T, et al. 2022. PLoS Pathog. 18:e1010302. PubMed
  140. Qin W, et al. 2021. FASEB J. 35:e21599. PubMed
  141. Zhang Q, et al. 2022. Nat Commun. 13:2406. PubMed
  142. Fan Q, et al. 2021. Bioact Mater. 6:4014. PubMed
  143. Koikawa K, et al. 2021. Cell. 184:4753. PubMed
  144. Parayath NN, et al. 2020. Nat Commun. 4.680555556. PubMed
  145. Arce-Cerezo A, et al. 2015. Sci Rep. 5: 1448. PubMed
  146. Torres I, et al. 2014. Infect Immun . 82:4689. PubMed
  147. Deng G, et al. 2010. J Immunol. 184:7154. PubMed
  148. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  149. Stifter SA, et al. 2019. Cell Rep. 29:3539. PubMed
  150. Tomay F, et al. 2019. J Transl Med. 17:237. PubMed
  151. Zheng X, et al. 2018. J Clin Invest. 128:2104. PubMed
  152. Taye B, et al. 2017. BMC Genomics . 10.1186/s12864-017-3803-6. PubMed
  153. Wang Y et al. 2017. Cell. 171(2):331-345 . PubMed
  154. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  155. Patankar Y, et al. 2015. Am J Physiol Lung Cell Mol Physiol. 309: L902 - L913. PubMed
  156. Uematsu T, et al. 2016. Sci Rep. 6:37815. PubMed
  157. Howard ZM, et al. 2022. JCI Insight. 7:. PubMed
  158. Miki Y, et al. 2022. JCI Insight. 7:. PubMed
  159. Anderson-Baucum E, et al. 2021. Cell Metab. 33:1883. PubMed
  160. Raoof R, et al. 2021. J Neurosci. 41:8249. PubMed
  161. Wang X, et al. 2022. J Biol Chem. 298:101561. PubMed
  162. Yuan M, et al. 2022. Oxid Med Cell Longev. 2022:5479491. PubMed
  163. Hou PP, et al. 2020. Molecular Cell. 78(6):1192-1206.e10. PubMed
  164. Sasaki Y, et al. 2015. PLoS One. 10: 0131176. PubMed
  165. Honda H, et al. 2014. J Leukoc Biol. 96:1087. PubMed
  166. Drori A, et al. 2014. PLoS One. 9:110942. PubMed
  167. Quick M, et al. 2012. Am J Physiol Regul Integr Comp Physiol. 303:580. PubMed
  168. Lu SW, et al. 2020. Nat Commun. 3.660416667. PubMed
  169. Fukushima K, et al. 2020. Immunity. 52(3):542-556. PubMed
  170. Li YT, et al. 2019. Elife. 8:e47642. PubMed
  171. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  172. Du H, et al. 2017. Nat Commun. 10.1038/s41467-017-00522-7. PubMed
  173. Nenasheva T, et al. 2017. PLoS One. 12(6):e0178983. PubMed
  174. Dongsheng Z, et al. 2017. Inflammation. 10.1007/s10753-017-0619-0. PubMed
  175. Di G, et al. 2017. Invest Ophthalmol Vis Sci. 10.1167/iovs.17-21506. PubMed
  176. Xia Y, et al. 2018. Cell. 175:1059. PubMed
  177. Osorio K, et al. 2011. J Cell Biol. 193:235. PubMed
  178. Chen Z, et al. 2016. PLoS One. 11: 0146681. PubMed
  179. Mothes B, et al. 2016. PLoS One. 11: 0159310. PubMed
  180. Yuan Y, et al. 2020. Front Physiol. 0.967361111. PubMed
  181. Bordas M, et al. 2020. Int J Mol Sci. 21:00. PubMed
  182. Lv JJ, et al. 2021. Front Cell Dev Biol. 8:609090. PubMed
  183. Yan T, et al. 2021. Toxicological Sciences. 181(2):273-284. PubMed
  184. Deng Q, et al. 2021. Gut Microbes. 13:1. PubMed
  185. Glasenapp A, et al. 2021. Circ Res. 129:369. PubMed
  186. Zheng X, et al. 2020. Int J Cancer. 146:1730. PubMed
  187. Lu Q, et al. 2022. Biomed Res Int. 2022:9427076. PubMed
  188. Nam J, et al. 2021. Adv Ther (Weinh). 4:. PubMed
  189. Howard ZM, et al. 2021. Am J Pathol. 191:730. PubMed
  190. Li Y, et al. 2020. Theranostics. 10:2897. PubMed
  191. Zhao H, et al. 2022. Commun Biol. 5:74. PubMed
  192. Lee SA, et al. 2021. Cells. 10:. PubMed
  193. Vaibhav K, et al. 2020. Sci Adv. 6:eaax8847. PubMed
  194. Zhou T, et al. 2021. Bioact Mater. 0.734027778. PubMed
  195. van Aalst S, et al. 2017. Vaccine. 10.1016/j.vaccine.2017.02.005. PubMed
  196. Meunier I, et al. 2015. PLoS One. 10: 0138055. PubMed
  197. Nasser H, et al. 2020. Cell Death Discov. 0.29375. PubMed
  198. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  199. Porrello A, et al. 2018. Nat Commun. 9:1988. PubMed
  200. Lancaster GI et al. 2018. Cell metabolism. 27(5):1096-1110 . PubMed
  201. Lang JF et al. 2019. Nat Commun. 10(1):3415 . PubMed
  202. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  203. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  204. Vazquez-Lombardi R, et al. 2017. Nat Commun. 8:15373. PubMed
  205. Elias I, et al. 2012. Diabetes. 61:1801. PubMed
  206. Schaffert S, et al. 2015. J Immunol. 195: 1470-1479. PubMed
  207. Morein D, et al. 2021. Cells. 10: . PubMed
  208. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  209. Zhang F, et al. 2021. J Immunol Res. 2021:5521051. PubMed
  210. Liu C, et al. 2022. Cell Death Discov. 8:269. PubMed
  211. Gautam S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. 319:L661. PubMed
  212. Mujal AM, et al. 2022. Cancer Immunol Res. 10:403. PubMed
  213. Rodriguez-Tirado C, et al. 2022. Cancers (Basel). 14:. PubMed
  214. Fite BZ, et al. 2021. Sci Rep. 11:927. PubMed
  215. Simoni L, et al. 2020. Cell Rep. 33:108330. PubMed
  216. Martins R, et al. 2016. Nat Immunol. 17:1361-1372. PubMed
  217. Kwon H, Kim S 2016. Cell Death Dis. 7:22285. PubMed
  218. Zhang J, et al. 2020. J Cell Mol Med. 24:4547. PubMed
  219. Albaghdadi AJH, et al. 2019. Sci Rep. 9:6528. PubMed
  220. Li B et al. 2019. Cell reports. 26(10):2720-2737 . PubMed
  221. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  222. Kurelac I, et al. 2019. J Clin Med. 1.85. PubMed
  223. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  224. Bhatia S, et al. 2019. Cancer Res. 79:2722. PubMed
  225. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  226. Caetano MS, et al. 2019. Clin Cancer Res. 25:7576. PubMed
  227. Bringmann G, et al. 2013. Antimicrob Agents Chemother. 57:3003. PubMed
  228. Tran S, et al. 2020. Immunity. 53(3):627-640.e5. PubMed
  229. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  230. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  231. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  232. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  233. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  234. Yang F, et al. 2021. Nat Commun. 12:3424. PubMed
  235. Cortez MA, et al. 2020. Nat Commun. 3.819444444. PubMed
  236. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
  237. Wegiel B, et al. 2014. Cell Death Dis. 5:1139. PubMed
  238. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  239. Deniset JF et al. 2019. Immunity. 51(1):131-140 . PubMed
  240. Kubli SP, et al. 2019. Nat Commun. 10:2678. PubMed
RRID
AB_893500 (BioLegend Cat. No. 123107)
AB_893500 (BioLegend Cat. No. 123108)

Antigen Details

Structure
EGF-TM7 family member, 160 kD glycoprotein
Distribution

Majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen, Kupffer cells, Langerhans cells, bone marrow stromal cells, and a subset of dendritic cells

Function
Induction of immunological tolerance
Cell Type
Dendritic cells, Langerhans cells, Macrophages, Tregs
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Antigen References

1. Austy JM and Gordon S. 1981. Eur. J. Immunol. 11:805.
2. Hume DA, et al. 1983. J. Exp. Med. 158:1522.
3. Ruedl C, et al. 1996. Eur. J. Immunol. 26:1801.
4. McKnight AJ, et al. 1996. J. Biol. Chem. 271:486.
5. Lin HH, et al. 2005. J. Exp. Med. 201:1615.

Gene ID
13733 View all products for this Gene ID
UniProt
View information about F4/80 on UniProt.org

Other Formats

View All F4/80 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 605™ anti-mouse F4/80 BM8 FC
Purified anti-mouse F4/80 BM8 FC,IHC,WB
Biotin anti-mouse F4/80 BM8 FC,IHC
FITC anti-mouse F4/80 BM8 FC
PE anti-mouse F4/80 BM8 FC
PE/Cyanine5 anti-mouse F4/80 BM8 FC
PE/Cyanine7 anti-mouse F4/80 BM8 FC
APC anti-mouse F4/80 BM8 FC
APC/Cyanine7 anti-mouse F4/80 BM8 FC
Alexa Fluor® 488 anti-mouse F4/80 BM8 FC,IHC-F,3D IHC
Alexa Fluor® 647 anti-mouse F4/80 BM8 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse F4/80 BM8 FC
PerCP anti-mouse F4/80 BM8 FC
PerCP/Cyanine5.5 anti-mouse F4/80 BM8 FC
Alexa Fluor® 700 anti-mouse F4/80 BM8 FC
Brilliant Violet 421™ anti-mouse F4/80 BM8 FC,IHC-F,SB
Brilliant Violet 510™ anti-mouse F4/80 BM8 FC
Alexa Fluor® 594 anti-mouse F4/80 BM8 IHC-F
Brilliant Violet 785™ anti-mouse F4/80 BM8 FC
Purified anti-mouse F4/80 (Maxpar® Ready) BM8 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse F4/80 BM8 FC
Brilliant Violet 650™ anti-mouse F4/80 BM8 FC
Brilliant Violet 711™ anti-mouse F4/80 BM8 FC
APC/Fire™ 750 anti-mouse F4/80 BM8 FC
TotalSeq™-A0114 anti-mouse F4/80 BM8 PG
TotalSeq™-B0114 anti-mouse F4/80 BM8 PG
TotalSeq™-C0114 anti-mouse F4/80 BM8 PG
Spark YG™ 570 anti-mouse F4/80 BM8 IHC-F
KIRAVIA Blue 520™ anti-mouse F4/80 BM8 FC
Ultra-LEAF™ Purified anti-mouse F4/80 BM8 FC,IHC,WB
APC/Fire™ 810 anti-mouse F4/80 BM8 FC
Spark NIR™ 685 anti-mouse F4/80 BM8 FC
Spark Blue™ 550 anti-mouse F4/80 BM8 FC
Brilliant Violet 570™ anti-mouse F4/80 BM8 FC
Brilliant Violet 750™ anti-mouse F4/80 BM8 FC
PE/Fire™ 810 anti-mouse F4/80 BM8 FC
Spark Red™ 718 anti-mouse F4/80 (Flexi-Fluor™) BM8 FC
Spark Blue™ 574 anti-mouse F4/80 (Flexi-Fluor™) BM8 FC
Go To Top Version: 2    Revision Date: 10/25/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login/Register
Remember me
Forgot your password? Reset Password
Request an Account