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- Clone
- M-B371 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- V CD37.4
- Other Names
- Tetraspanin26, tspan-26, GP52-40
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with purified CD37 (clone M-B371, filled histogram) or mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG FITC.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 356301 | 25 µg | $65 | ||||
| 356302 | 100 µg | $134 | ||||
CD37 is a 40-52 kD type II transmembrane protein, also known as tetraspanin-26. It is a member of the transmembrane tetraspanin family. It can interact with integrins and other transmembrane 4 superfamily members (CD53, CD81, CD82). CD37 is expressed predominantly on B cells; low expression is detected on T cells and myeloid cells. No expression is reported on NK cells and plasma cells. It is involved in regulation of T cell proliferation.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue sections1.
-
Application References
(PubMed link indicates BioLegend citation) -
- Leshchenko VV. et al. 2010. Blood 116:1025. (FC, IHC)
- RRID
-
AB_2561772 (BioLegend Cat. No. 356301)
AB_2561772 (BioLegend Cat. No. 356302)
Antigen Details
- Structure
- 40-52 kD, type II integral membrane protein
- Distribution
-
B cells, weak expression on T cells and myeloid cells
- Function
- Involved in regulation of T cell proliferation
- Ligand/Receptor
- α3β1
- Cell Type
- B cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Moore K, et al. 1987. J. Pathol. 152:13.
2. Schwartz-Albiez R, et al. 1988. J. Immunol. 140:905. - Gene ID
- 951 View all products for this Gene ID
- UniProt
- View information about CD37 on UniProt.org
Other Formats
View All CD37 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD37 | M-B371 | FC,IHC-F |
| FITC anti-human CD37 | M-B371 | FC |
| TotalSeq™-A0941 anti-human CD37 | M-B371 | PG |
| TotalSeq™-C0941 anti-human CD37 | M-B371 | PG |
| TotalSeq™-B0941 anti-human CD37 | M-B371 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD37
Human peripheral blood lymphocytes were stained with purifie... -
FITC anti-human CD37
Human peripheral blood lymphocytes were stained with CD37 (c... -
TotalSeq™-A0941 anti-human CD37
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TotalSeq™-C0941 anti-human CD37
-
TotalSeq™-B0941 anti-human CD37
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