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Purified anti-Tubulin β 3 (TUBB3) Antibody (Previously Covance catalog# MMS-435P)

Pricing & Availability
Clone
TUJ1 (See other available formats)
Regulatory Status
RUO
Other Names
CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, Tubulin beta-3 chain, tubulin beta-III, tubulin beta-4 chain, class III beta-tubulin
Previously
Covance Catalog# MMS-435P
Isotype
Mouse IgG2a, κ
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Product Citations
publications
A_TUJ1_PURE_Tubulin-beta3_IHCP_Hu_011618
IHC staining of purified anti-Tubulin β 3 (TUBB3) antibody (clone TUJ1) on formalin-fixed paraffin-embedded human brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with 1 µg/mL of the primary antibody overnight at 4°C. BioLegend’s Ultra Streptavidin (USA) HRP Detection Kit (Multi-Species, DAB, Cat. No. 929901) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective.
  • A_TUJ1_PURE_Tubulin-beta3_IHCP_Hu_011618
    IHC staining of purified anti-Tubulin β 3 (TUBB3) antibody (clone TUJ1) on formalin-fixed paraffin-embedded human brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with 1 µg/mL of the primary antibody overnight at 4°C. BioLegend’s Ultra Streptavidin (USA) HRP Detection Kit (Multi-Species, DAB, Cat. No. 929901) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective.
  • B_TUJ1_PURE_Tubulin-beta3_IHCP_Rat_011618
    IHC staining of purified anti-Tubulin β 3 (TUBB3) antibody (clone TUJ1) on formalin-fixed paraffin-embedded rat brain tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with 0.5 µg/mL of the primary antibody overnight at 4°C. BioLegend’s Ultra Streptavidin (USA) HRP Detection Kit (Multi-Species, DAB, Cat. No. 929901) was used for detection followed by hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective.
  • C_TUJ1_PURE_Tubulin-beta3_WB_011618
    Western blot of purified anti-Tubulin β 3 (TUBB3) antibody (clone TUJ1). Lane 1: Molecular weight marker; Lane 2: 20 µg of human brain lysate; Lane 3: 20 µg of Mouse brain lysate; Lane 4: 20 µg of rat brain lysate. The blots were incubated with 1 ug/mL of TUJ1 or mouse IgG overnight at 4°C, followed by incubation with HRP-labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
  • D_TUJ1_PURE_Tubulin-beta3_ICC_011618
    ICC staining of purified anti-Tubulin β 3 (TUBB3) antibody (clone TUJ1) on SH-SY5Y neuroblastoma cells. The cells were fixed by 4% PFA, permeabilized with a buffer containing 0.1% Triton X-100 and 0.25% BSA, and blocked with 2% Normal Goat Serum and 0.02% BSA. The cells were then incubated with 1 µg/mL of the primary antibody for 3 hours at room temperature, followed by incubation with 0.5 µg/mL Alexa Fluor® 594 goat anti-mouse IgG (Cat. No. 405326) for 1 hour at room temperature. Nuclei were counterstained with DAPI. The image was captured with a 60X objective Scale bar: 20 µm
  • E_Ankita_Patil
    Methanol fixed superior cervical ganglion neurons were stained with anti-tubulin β3 (pink) and anti-TRIM46 (aqua), then stained with secondary antibodies, phalloidin (orange) and DAPI (blue). Image generously submitted to the 2017 Cell Life Imaging Competition by Ankita Patil from Drexel University.
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801213 25 µL $106
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801201 100 µL $265
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801202 250 µL $391
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Description

Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors. Studies indicate that it is a predictive and prognostic marker in various tumors.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This antibody was raised against microtubules derived from rat brain.
Formulation
Phosphate-buffered solution + 0.03% Thimerosal.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1.0 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

IHC-P - Quality tested
WB, ICC - Verified
FC - Reported in the literature, not verified in house
SB - Community verified
Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 5.0 µg/ml is suggested. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 µg/ml. For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: flow cytometry4, immunofluorescence microscopy1-5,7, immunohistochemistry5,7, Western blotting8, and spatial biology (IBEX)9,10.

This antibody is well characterized and highly reactive to neuron specific Class III ß-tubulin (ßIII). TUJ1 does not identify ß-tubulin found in glial cells. TUJ1 recognizes an epitope located within the last 15 C-terminal residues8.

Additional Product Notes

This product has been verified for IHC-F (Immunohistochemistry - frozen tissue sections) on the NanoString GeoMx® Digital Spatial Profiler. The GeoMx® enables researchers to perform spatial analysis of protein and RNA targets in FFPE and fresh frozen human and mouse samples. For more information about our spatial biology products and the GeoMx® platform, please visit our spatial biology page.

Application References

(PubMed link indicates BioLegend citation)
  1. Nishimura K, et al. 2017. PLoS One. 12(1): e0170568. (ICC)
  2. Jongbloets J, et al. 2017. Nat Commun. 8: 14666. (ICC) PubMed
  3. Liu W.J, et al. 2015. Eur J Histochem. 59(1): 2464. (ICC) PubMed
  4. Chintalapudi SR, et al. 2016. Front Aging Neursci. 8:93. (FC, ICC) PubMed
  5. Ambasudhan R, et al. 2011. Cell Stem Cell. 9(2):113. (IHC, ICC)
  6. Hu X., et al. 2006. Nature Neuroscicene. 9(12):1520. (WB) PubMed
  7. Zechner D., et al. 2003. Develop Biology. 258(2):406. (ICC, IHC)
  8. Lee MK, et al. 1990. Proc. Natl. Acad. Sci. USA 18:7195. (WB)
  9. Radtke AJ, et al. 2020. Proc Natl Acad Sci USA. 117:33455-33465. (SB) PubMed
  10. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Gai M, et al. 2016. EMBO Rep. 17: 1396 - 1409. PubMed
  2. Nonomura K, et al. 2016. Nature. 541:176-181. PubMed
  3. Ueki J, et al. 2017. Sci Rep. 7:42522. PubMed
  4. Fernandes HJR, et al. 2020. Cell Rep. 33:108263. PubMed
  5. Ko KW, et al. 2020. J Cell Biol. 219:00:00. PubMed
  6. Tilak M, et al. 2021. Molecular Cancer Research. 19(5):757-770. PubMed
  7. Alonso-Barroso E, et al. 2017. Stem Cell Research. 23:173-177. PubMed
  8. Wang YL, et al. 2021. Cell Reports. 36(8):109537. PubMed
  9. Tristan CA, et al. 2020. bioRxiv. . PubMed
  10. Abey A, et al. 2020. Brain Pathol. 31:144. PubMed
  11. Birsa N, et al. 2021. Sci Adv. 7: . PubMed
  12. Castelli LM, et al. 2021. Mol Neurodegener. 16:53. PubMed
  13. Nakayama T, et al. 2021. Cell Rep Med. 2:100421. PubMed
  14. Ye M, et al. 2021. Cell Death Dis. 12:1149. PubMed
  15. Seebauer L, et al. 2022. Int J Mol Sci. 23:. PubMed
  16. Zainul Z, et al. 2022. Sci Rep. 12:3344. PubMed
  17. Ahangari N, et al. 2021. J Neuropathol Exp Neurol. 80:944. PubMed
  18. Dang LT, et al. 2021. Dev Neurobiol. 81:696. PubMed
  19. Tsefou E, et al. 2021. Biochem J. 478:4099. PubMed
  20. Jacquier A, et al. 2022. Acta Neuropathol. 144:707. PubMed
  21. Wang Z, et al. 2022. Research (Wash D C). 2022:9832128. PubMed
  22. Schroeter MS, et al. 2022. MRS Bull. 47:530. PubMed
  23. Piermarini E, et al. 2022. Hum Mol Genet. 31:1844. PubMed
  24. Sun X, et al. 2022. Dev Cell. 57:112. PubMed
  25. Grigor'eva EV 2021. Stem Cell Research. 59:102651. PubMed
  26. Muralidharan H, et al. 2022. J Neurosci. 42:2149. PubMed
  27. Zhang A, et al. 2022. EMBO J. 41:e109187. PubMed
  28. Clements RT 2022. eneuro. 9(2). PubMed
  29. Sosnowski P, et al. 2022. Pharmaceuticals (Basel). 15: . PubMed
  30. Hallacli E, et al. 2022. Cell. 185:2035. PubMed
  31. Lin L, et al. 2022. J Comp Neurol. 530:2820. PubMed
  32. Park SY, et al. 2022. Int J Mol Sci. 23: . PubMed
  33. Hoye ML, et al. 2022. Elife. 11: . PubMed
  34. Wu X, et al. 2022. Cell Rep. 40:111085. PubMed
  35. Januel C, et al. 2022. Cell Mol Life Sci. 79:441. PubMed
  36. Frederico B, et al. 2022. Dev Cell. 57:1957. PubMed
  37. Xu J, et al. 2022. Small. 18:e2203431. PubMed
  38. Fleck JS, et al. 2022. Nature. :. PubMed
  39. Liu S, et al. 2023. CNS Neurosci Ther. 29:228. PubMed
  40. Radwitz J, et al. 2022. Cell Mol Life Sci. 79:575. PubMed
  41. Krasnova OA, et al. 2022. Int J Mol Sci. 23: . PubMed
  42. Vrathasha V, et al. 2022. iScience. 25:105308. PubMed
  43. Liu C, et al. 2022. Cell Mol Life Sci. 79:596. PubMed
  44. Koizumi M, et al. 2022. FASEB J. 36:e22662. PubMed
  45. Herdy JR 2022. Cell Stem Cell. 29(12):1637-1652.e6. PubMed
  46. Zhou Z, et al. 2023. Biol Pharm Bull. 46:102. PubMed
  47. Santiago-Mujika E, et al. 2023. J Alzheimers Dis Rep. 6:739. PubMed
  48. Xue W, et al. 2023. iScience. 26:105898. PubMed
  49. Jin S, et al. 2023. iScience. 26:105885. PubMed
  50. Day C, et al. 2023. Pharmaceuticals (Basel). 16: . PubMed
  51. Willumsen N, et al. 2023. Brain Commun. 5:fcac321. PubMed
  52. Choi EB, et al. 2023. J Biol Chem. 299:102996. PubMed
  53. Ma Y, et al. 2023. Eneuro. 10: . PubMed
  54. Wu W, et al. 2021. Nature. 593:440. PubMed
  55. Le Floch P, et al. 2022. Adv Mater. 34:e2106829. PubMed
  56. Alonso-Alonso S, et al. 2022. Reprod Fertil Dev. 34:576. PubMed
  57. Marrone L, et al. 2022. Hum Mol Genet. 31:2693. PubMed
  58. Hamrangsekachaee M, et al. 2022. ACS Appl Bio Mater. 5:2176. PubMed
  59. Lee J, et al. 2022. Nat Protoc. 17:1266. PubMed
  60. Urbaniak A, et al. 2022. Biomed Pharmacother. 153:113440. PubMed
  61. Dong C, et al. 2022. J Neurosci. 42:8373. PubMed
  62. Krasniewski LK, et al. 2022. Elife. 11:. PubMed
  63. Baek J, et al. 2022. Biomater Sci. 10:6768. PubMed
  64. Li TL, et al. 2022. Biomaterials. 290:121825. PubMed
  65. Cattelani C, et al. 2022. Int J Mol Sci. 23:. PubMed
  66. Chen WJ, et al. 2022. Adv Sci (Weinh). :e2205451. PubMed
  67. Wu J, et al. 2022. Methods Mol Biol. 2593:245. PubMed
  68. Whye D, et al. 2023. Curr Protoc. 3:e641. PubMed
  69. Dong Z, et al. 2023. J Biol Chem. 299:103020. PubMed
  70. Campbell B, et al. 2023. Sci Rep. 13:3000. PubMed
  71. Loan A, et al. 2023. iScience. 26:106093. PubMed
  72. Jimenez-Moreno N, et al. 2023. J Cell Biol. 222:. PubMed
  73. Panzi C, et al. 2023. Toxicon. 228:107110. PubMed
  74. Cossec JC, et al. 2023. Cell Rep. 42:112380. PubMed
  75. Eigenhuis KN, et al. 2023. Front Cell Neurosci. 17:1114420. PubMed
  76. Gilbert-Jaramillo J, et al. 2023. Biol Open. 12:. PubMed
  77. Sim KY, et al. 2023. Sci Rep. 13:6864. PubMed
  78. D'aes T, et al. 2023. Int J Mol Sci. 24:. PubMed
  79. Dawicki-McKenna JM, et al. 2023. Nat Commun. 14:2628. PubMed
  80. Paranjape N, et al. 2023. Sci Rep. 13:7689. PubMed
  81. Nguyen TTM, et al. 2023. iScience. 26:106674. PubMed
  82. Georgelou K, et al. 2023. Biomedicines. 11:. PubMed
  83. Kerkering J, et al. 2023. J Clin Invest. . PubMed
  84. Liang MZ, et al. 2023. Cell Biosci. 13:96. PubMed
  85. Lin CY, et al. 2023. J Food Drug Anal. 31:32. PubMed
  86. Martínez-Torres S, et al. 2023. iScience. 26:106814. PubMed
  87. Dos Santos BL, et al. 2023. Pharmaceutics. 15:. PubMed
  88. Stajkovic N, et al. 2023. J Cell Sci. . PubMed
  89. Drobny S, et al. 2023. Transl Neurodegener. 12:31. PubMed
  90. Zhang M, et al. 2023. Neurosci Bull. . PubMed
  91. Boyer NP, et al. 2018. Eneuro. 55:1847. PubMed
  92. Lee SW et al. 2018. Developmental cell. 46(1):73-84 . PubMed
  93. Chia PH et al. 2018. eLife. 7 pii: e32451. PubMed
  94. Erwig MS, et al. 2019. Elife. 8:. PubMed
  95. Tohgi N, et al. 2017. Cell Cycle. 16:95. PubMed
  96. Nicole O, et al. 2018. Mol Psychiatry. 23:2209. PubMed
  97. Kirihara T, et al. 2019. iScience. 14:301. PubMed
  98. Sanli I, et al. 2018. Cell Rep. 23:337. PubMed
  99. Croteau LP, et al. 2019. Sci Rep. 9:12009. PubMed
  100. Ioannou MS et al. 2019. Cell. 177(6):1522-1535 . PubMed
  101. Paonessa F et al. 2019. Cell reports. 26(3):582-593 . PubMed
  102. de la Cerda B et al. 2019. Stem cell research. 1726:26:00 . PubMed
  103. García‐Peña CM et al. 2018. Frontiers in neuroanatomy. 0.566666667 . PubMed
  104. Coleman JH, et al. 2017. J Comp Neurol. 525:3391. PubMed
  105. Abud EM et al. 2017. Neuron. 94(2):278-293 . PubMed
  106. Huang YA et al. 2017. Cell. 168(3):427-441 . PubMed
  107. Hegarty DM, et al. 2018. Pain Rep. 3:e664. PubMed
  108. Dai WJ, et al. 2019. Evid Based Complement Alternat Med. 2019:8413576. PubMed
  109. Wang XW, et al. 2020. Cell Rep. 31:107537. PubMed
  110. Woeste MA, et al. 2019. J Biol Chem. 294:3853. PubMed
  111. Tian R, et al. 2019. Neuron. 104:239. PubMed
  112. Xia F, et al. 2021. Acta Neuropathol Commun. 51:9. PubMed
  113. Shin BC, et al. 2021. Experimental Neurology. 338:113603. PubMed
  114. Wang D, et al. 2020. Journal of Biological Chemistry. 295(25):8374-8386. PubMed
  115. Khoa LTP, et al. 2020. Cell Stem Cell. 27(3):441-458.e10. PubMed
  116. Domènech EB, et al. 2020. Invest Ophthalmol Vis Sci. 61:14:00. PubMed
  117. Elhardt C, et al. 2020. Transl Vis Sci Technol. 9:06. PubMed
  118. Lee SE, et al. 2020. Cell Death Dis. 1.19375. PubMed
  119. Babetto E, et al. 2020. Nat Neurosci. 23:1215. PubMed
  120. Eltahir MK, et al. 2022. PLoS One. 17:e0269683. PubMed
  121. Simoes S, et al. 2021. Cell Rep. 37:110182. PubMed
  122. Viais R, et al. 2021. Elife. 10:. PubMed
  123. Lafarga V, et al. 2021. EMBO J. 40:e103311. PubMed
  124. Kim S, et al. 2021. Nat Commun. 12:1807. PubMed
  125. Brown AL, et al. 2022. Nature. 603:131. PubMed
  126. Ruden JB, et al. 2021. Front Mol Neurosci. 14:777049. PubMed
  127. Tseng JH, et al. 2021. Cell Rep. 35:109037. PubMed
  128. Guo B, et al. 2021. Front Cell Dev Biol. 9:768970. PubMed
  129. Li F, et al. 2021. Nat Commun. 12:3845. PubMed
  130. Orozco-Díaz R, et al. 2019. PLoS One. 14:e0220393. PubMed
  131. Arber C, et al. 2019. Brain Commun. 1:fcz024. PubMed
  132. Valès S, et al. 2019. EBioMedicine. 49:172. PubMed
  133. Teissier A, et al. 2019. Mol Psychiatry. :. PubMed
  134. Macova I, et al. 2019. J Neurosci. 39:984. PubMed
  135. Inoue SI, et al. 2017. Hum Mol Genet. 26:4715. PubMed
  136. Shepherd DJ et al. 2017. Journal of neuropathology and experimental neurology. 76(8):683-696 . PubMed
  137. Kow Essuman et al. 2017. Neuron. 93(6):1334-1343 . PubMed
  138. Mangold CA et al. 2018. J Neurochem. 144(6):723-735 . PubMed
  139. Levin E et al. 2019. Cell reports. 26(4):1021-1032 . PubMed
  140. Murcia-Belmonte V, et al. 2019. Curr Biol. 29:1149. PubMed
  141. Daoutsali E et al. 2019. Stem Cell Res. 1723:19:00 . PubMed
  142. Ogawa Y et al. 2019. Neurosci Res. pii: S0168-0102(19)30120-8 . PubMed
  143. Tiethof AK, et al. 2018. Toxics. 6:52. PubMed
  144. Boso D, et al. 2019. Theranostics. 9:4860. PubMed
  145. Cha HL, et al. 2019. Mol Brain. 12:57. PubMed
  146. Wang G et al. 2019. eLife. 8 pii: e38730. PubMed
  147. Vinci M, et al. 2018. Nat Med. 24:1204. PubMed
  148. Laussu J, et al. 2017. Neural Dev. 12:10. PubMed
  149. Hu X, et al. 2019. Stem Cell Reports. 12:290. PubMed
  150. Valadas JS et al. 2018. Neuron. 98(6):1155-1169 . PubMed
  151. Ziller MJ, et al. 2018. Cell Stem Cell. 1.304861111. PubMed
  152. Park SY, et al. 2018. Mol Brain. 169:91. PubMed
  153. Kishi N, et al. 2016. Nat Commun. 7:10520. PubMed
  154. Nawaz M, et al. 2016. PLoS One. 11: 0148634. PubMed
  155. Tao W, et al. 2020. EMBO Mol Med. 12:e12291. PubMed
  156. Bae B, et al. 2020. RNA. 26:1414. PubMed
  157. Halikere A, et al. 2020. Mol Psychiatry. 25:1406. PubMed
  158. Song JM, et al. 2021. The Journal of Neuroscience. 41(11):2344-2359. PubMed
  159. Benito-Kwiecinski S, et al. 2021. Cell. 184(8):2084-2102.e19. PubMed
  160. Bayerl J, et al. 2021. Cell Stem Cell. . PubMed
  161. Eriksen AZ, et al. 2021. Cell Stem Cell. 28(7):1205-1220.e7. PubMed
  162. Elsayed AK, et al. 2021. Stem Cell Research. 54:102433. PubMed
  163. Lpez-Mrquez A, et al. 2019. Stem Cell Research. 38:101469. PubMed
  164. Sood S, et al. 2020. Proc Natl Acad Sci U S A. 22331:117. PubMed
  165. Lim SH, et al. 2020. J Cell Sci. :133. PubMed
  166. Yun T, et al. 2021. Cell Death Discov. 7:257. PubMed
  167. Herbst WA, et al. 2021. J Cell Biol. 220:. PubMed
  168. Heinrich A, et al. 2021. Cell Rep. 37:109885. PubMed
  169. Earley AM, et al. 2021. Sci Rep. 11:22257. PubMed
  170. Ramirez S, et al. 2021. STAR Protoc. 2:100987. PubMed
  171. Valenzuela M, et al. 2022. Stem Cell Res Ther. 13:261. PubMed
  172. Richardson RT, et al. 2021. Sci Rep. 11:11229. PubMed
  173. Guo X, et al. 2021. Cell. 184:4299. PubMed
  174. Vilallongue N, et al. 2022. Nat Commun. 13:6040. PubMed
  175. Coste C, et al. 2017. PLoS One. 10.1371/journal.pone.0177962. PubMed
  176. Miranda AM, et al. 2018. Nat Commun. 9:291. PubMed
  177. Liu C, et al. 2018. Stem Cell Reports. 4:43. PubMed
  178. Lee SY et al. 2018. Stem cell research. 30:145-149 . PubMed
  179. Vitali I et al. 2018. Cell. 174(5):1264-1276 . PubMed
  180. Roselló-Busquets C, et al. 2019. Front Cell Neurosci. 13:40. PubMed
  181. Stepp MA, et al. 2018. Int J Mol Sci. 19:12. PubMed
  182. Miltner AM, et al. 2019. Int J Mol Sci. 20. PubMed
  183. Canali G, et al. 2018. Hum Mol Genet. 27:1941. PubMed
  184. Haverfield JT, et al. 2017. Reprod Fertil Dev. 29:609. PubMed
  185. Arellano‐Viera E et al. 2019. Stem cell research. 1726:10:00 . PubMed
  186. Ribic A et al. 2019. Cell reports. 26(2):381-393 . PubMed
  187. Varga E et al. 2017. Stem cell research. 25:30-33 . PubMed
  188. Nguyen HX et al. 2014. The Journal of comparative neurology. 522(12):2767-83 . PubMed
  189. Bonnefont J, et al. 2019. Neuron. 103:1096. PubMed
  190. Giandomenico SL, et al. 2019. Nat Neurosci. 22:669. PubMed
  191. Stratton JA, et al. 2020. Front Aging Neurosci. 0.620833333. PubMed
  192. Lennox AL, et al. 2020. Neuron. 404:106. PubMed
  193. Pecori F, et al. 2021. Cell Reports. 36(2):109361. PubMed
  194. Aarts CEM, et al. 2021. Stem Cell Research. 54:102444. PubMed
  195. Zhang K, et al. 2021. Neuron. 109(12):1949-1962.e6. PubMed
  196. Aprigliano R, et al. 2021. Cell Reports Medicine. 2(4):100240. PubMed
  197. Pantier R, et al. 2021. Molecular Cell. 81(4):845-858.e8. PubMed
  198. Parlanti P, et al. 2020. Exp Eye Res. 194:107998. PubMed
  199. Toma JS, et al. 2020. Eneuro. 7:00. PubMed
  200. Solis-Castro OO, et al. 2020. Stem Cells Transl Med. 1.390277778. PubMed
  201. Ucuncu E, et al. 2020. Nat Commun. 4.685416667. PubMed
  202. LI Y, et al. 2017. Proc Natl Acad Sci U S A. 114(2):E209-E218. PubMed
  203. Jiang G, et al. 2016. Stem Cells Trans Med. 5(12):1595-1606. PubMed
  204. Martin C, et al. 2016. Genes Dev. 30: 2158 - 2172. PubMed
  205. Kida H, et al. 2016. Cereb Cortex. 10.1093/cercor/bhw134. PubMed
  206. Masumoto K, et al. 2022. Sci Rep. 12:10351. PubMed
  207. McClellan S, et al. 2021. Invest Ophthalmol Vis Sci. 62:14. PubMed
  208. Hagihara H, et al. 2021. Cell Rep. 37:109820. PubMed
  209. Boussaad I, et al. 2021. Sci Rep. 11:1439. PubMed
  210. Savino E, et al. 2021. Cells. 10:. PubMed
  211. Liu X, et al. 2021. Cell Prolif. 54:e13124. PubMed
  212. Doron-Mandel E, et al. 2021. EMBO J. 40:e107158. PubMed
  213. Savino E, et al. 2020. Cell Death Dis. 1.052777778. PubMed
  214. Saito K, et al. 2019. Cell Rep. 29:1555. PubMed
  215. Lilian SJ, et al. 2019. J Assoc Res Otolaryngol. 20:133. PubMed
  216. Milbreta U, et al. 2019. Mol Ther. 27:411. PubMed
  217. Arai Y, et al. 2019. Cell Rep. 29:645. PubMed
  218. Bucan V, et al. 2019. Int J Mol Med. 43:593. PubMed
  219. Petkovich DA et al. 2017. Cell metabolism. 25(4):954-960 . PubMed
  220. Auboyer L et al. 2019. Stem Cell Res. 1727:38:00 . PubMed
  221. Tomassoni–Ardori F, et al. 2019. Elife. 8:e46677. PubMed
  222. Van Der Raadt J, et al. 2019. Nucleic Acids Res. 47:5587. PubMed
  223. Raspa A, et al. 2019. CNS Neurosci Ther. 25:86. PubMed
  224. González C, et al. 2018. Mol Psychiatry. 23:2363. PubMed
  225. Liu H, et al. 2019. Front Cell Neurosci. 13:60. PubMed
  226. Mura M et al. 2018. Stem cell research. 29:170-173 . PubMed
  227. Hermanto Y et al. 2018. Journal of neuroscience research. 96(5):863-874 . PubMed
  228. Playne R, et al. 2018. J Stem Cells Regen Med. 7:e36998. PubMed
  229. Allende ML, et al. 2018. J Lipid Res. 59:550. PubMed
  230. Kim K, et al. 2015. PLoS One. 10: 0142693. PubMed
  231. Mazzulli J, et al. 2016. Proc Natl Acad Sci U S A. 113: 1931 - 1936. PubMed
  232. Soares V, et al. 2016. Neuro Oncology. 10.1093/neuonc/now099. PubMed
  233. Mikami Y, et al. 2016. EBioMedicine. 11: 253-261. PubMed
  234. Pal-Ghosh S, et al. 2020. Invest Ophthalmol Vis Sci. 61:01:00. PubMed
  235. Janz A, et al. 2021. Stem Cell Research. 53:102256. PubMed
  236. Iwasa N, et al. 2021. Front Cell Neurosci. 15:605030. PubMed
  237. Boshans LL, et al. 2021. Sci Rep. 11:3552. PubMed
  238. Weiss FD, et al. 2021. Nat Commun. 12:2919. PubMed
  239. Mallach A, et al. 2021. Cells. 10:. PubMed
  240. Hernandez-Clavijo A, et al. 2022. Cell Physiol Biochem. 56:254. PubMed
  241. Wang W, et al. 2021. EMBO J. 40:e106771. PubMed
  242. Lin YC, et al. 2021. Nat Neurosci. 24:1077. PubMed
  243. Lim JY, et al. 2021. Stem Cell Res Ther. 12:402. PubMed
  244. Mifsud KR, et al. 2021. Nat Commun. 12:4737. PubMed
  245. Li Y, et al. 2022. Front Neurosci. 16:945277. PubMed
  246. Janssens S, et al. 2018. mSystems. 3. PubMed
  247. Thomas RA et al. 2018. eNeuro. 5(4) pii: ENEURO. PubMed
  248. Tripathy R, et al. 2018. Neuron. 100:1354. PubMed
  249. Lenz KM, et al. 2018. J Neurosci. 38:8044. PubMed
  250. Nam H et al. 2019. Elife. 8 pii: e46683. PubMed
  251. Boucherie C, et al. 2018. Mol Psychiatry. 23:723. PubMed
  252. Leibinger M et al. 2019. Commun Biol. 0.304166667 . PubMed
  253. Mura M et al. 2019. Stem Cell Res. 1727:37:00 . PubMed
  254. Hansen M et al. 2017. Stem cell research. 25:34-37 . PubMed
  255. Yang SC, et al. 2019. FASEB J. 33:10577. PubMed
  256. Qiang L, et al. 2019. Hum Mol Genet. 28:1136. PubMed
  257. Mura M, et al. 2019. Stem Cell Research. 42:101658. PubMed
  258. Alkobtawi M, et al. 2021. Cell Reports. 35(12):109289. PubMed
  259. Li W, et al. 2021. Stem Cell Research. 53:102259. PubMed
  260. Haas M, et al. 2016. Cell Rep. 15:2251-2265. PubMed
  261. Itoh Y, et al. 2016. Proc Natl Acad Sci U S A. 113: 2955 - 2964. PubMed
  262. Nagao M, et al. 2016. Nat Commun. 7:11102. PubMed
  263. Taverna E, et al. 2016. Sci Rep. 6:21206. PubMed
  264. Ulbrich L, et al. 2016. Biochem J. 473: 423 - 434. PubMed
  265. Barry D, et al. 2012. J Neurosci. 32:6209-6219. PubMed
  266. Iyer AA, et al. 2022. Elife. 11:. PubMed
  267. Cheng Y, et al. 2022. Nat Commun. 13:4418. PubMed
  268. Ramirez S, et al. 2021. Cells. 10:. PubMed
  269. Wareham LK, et al. 2021. iScience. 24:103141. PubMed
  270. Abe K, et al. 2021. Biophys J. 120:3566. PubMed
  271. Catanese A, et al. 2019. Autophagy. 15:1719. PubMed
  272. Pettingill P, et al. 2019. Brain. 142:3852. PubMed
  273. Wang SE, et al. 2019. Exp Neurobiol. 28:537. PubMed
  274. Song Z, et al. 2019. Front Cell Dev Biol. 0.352083333. PubMed
  275. Wang L et al. 2016. The Journal of comparative neurology. 524(11):2322-34 . PubMed
  276. Hansen M et al. 2017. Stem cell research. 25:42-45 . PubMed
  277. Herdy J et al. 2019. Elife. 8 pii: e41356. PubMed
  278. Vicario N et al. 2019. Molecular neurobiology. 56(11):7338-7354 . PubMed
  279. Child KM et al. 2018. The Journal of Neuroscience. 38(31):6806-6824 . PubMed
  280. Fujitani M, et al. 2017. Mol Psychiatry. 22:364. PubMed
  281. Hockman D, et al. 2018. Dev Biol. 444:s308. PubMed
  282. Barbiero I, et al. 2017. Hum Mol Genet. 26:3520. PubMed
  283. Coleman JH, et al. 2019. J Neurosci. 39:814. PubMed
  284. Luo C et al. 2019. eLife. 8 pii: e40197. PubMed
  285. Liu L et al. 2017. Cell metabolism. 26(5):719-737 . PubMed
  286. Knudsen JG et al. 2018. Cell metabolism. 29(2):430-442 . PubMed
  287. Millan‐Zambrano G et al. 2018. Molecular cell. 72(4):625-635 . PubMed
  288. Sevilla A et al. 2018. Stem cell research. 29:99-102 . PubMed
  289. Muthusamy N, et al. 2018. Sci Rep. 8:1766. PubMed
  290. Caiazzo M, et al. 2016. Nat Mater. 0.1038/nmat4536. PubMed
  291. Fan C, et al. 2016. Sci Rep. 6:19579. PubMed
  292. Vanderperre B, et al. 2016. PLoS Genet. 12: 1006056. PubMed
  293. Wang T, et al. 2016. Nat Commun. 7: 12976. PubMed
  294. Pei S, et al. 2016. Sci Rep. 6:33822. PubMed
  295. M Rodriguez, S Noctor, E Muñoz 2016. PLoS One. 11:e0167063. PubMed
  296. Ahn LY, et al. 2021. J Neurosci Res. 99:110. PubMed
  297. Black JB, et al. 2020. Cell Rep. 33:108460. PubMed
  298. Birkhoff JC, et al. 2020. Hum Mol Genet. 29:2535. PubMed
  299. Pereiro X, et al. 2020. Cells. 9:00. PubMed
  300. Berenguer-Escuder C, et al. 2020. Human Molecular Genetics. 29(8):1353-1364. PubMed
  301. Tapias A, et al. 2021. eLife. 10:00. PubMed
  302. Dong L, et al. 2021. Stem Cell Research. 53:102260. PubMed
  303. Zhang T, et al. 2021. STAR Protocols. 2(1):100346. PubMed
  304. Arribas-Carreira L, et al. 2019. Stem Cell Research. 39:101503. PubMed
  305. Schoger E, et al. 2021. Stem Cell Research. 56:102518. PubMed
  306. Klima S, et al. 2020. ALTEX. . PubMed
  307. Guerriero I, et al. 2021. PLoS One. 16:e0253828. PubMed
  308. Diao X, et al. 2021. Cells. 10:. PubMed
  309. Lamotte JD, et al. 2021. Front Pharmacol. 11:617867. PubMed
  310. Paik S, et al. 2021. Biomedicines. 9:. PubMed
  311. Nehme R, et al. 2022. Nat Commun. 13:3690. PubMed
  312. Xia L, et al. 2022. Front Pharmacol. 13:881195. PubMed
  313. Zhang L, et al. 2022. Front Aging Neurosci. 14:926485. PubMed
  314. Lu P, et al. 2022. Invest Ophthalmol Vis Sci. 63:18. PubMed
  315. Heuermann ML, et al. 2022. Front Cell Neurosci. 16:841864. PubMed
  316. McSweeney D, et al. 2022. iScience. 25:105187. PubMed
  317. Kuwahara H, et al. 2018. Sci Rep. 8:4377. PubMed
  318. Anne Jacob et al. 2018. Journal of neurochemistry. 146(3):251-268 . PubMed
  319. Lehrman EK et al. 2018. Neuron. 100(1):120-134 . PubMed
  320. Valdez C, et al. 2017. Hum Mol Genet. 26:4861. PubMed
  321. Moakley D, et al. 2019. Sci Rep. 9:10835. PubMed
  322. Malkemper EP, et al. 2018. Biol Open. 7:bio034462. PubMed
  323. Stratton JA et al. 2018. Cell reports. 24(10):2561-2572 . PubMed
  324. Neurohr GE, et al. 2019. Cell. 176:1083. PubMed
  325. Hermanto Y et al. 2019. Journal of neuroscience research. 97(7):828-845 . PubMed
  326. An D, et al. 2019. Elife. 8:e44423. PubMed
  327. Voronova A et al. 2017. Neuron. 94(3):500-516 . PubMed
  328. Hilla AM et al. 2017. The Journal of Neuroscience. 37(25):6113-6124 . PubMed
  329. Bustos F, et al. 2018. Cell Rep. 2.06875. PubMed
  330. Mayanagi T, et al. 2020. Front Cell Neurosci. 0.933333333. PubMed
  331. Arsić A, et al. 2020. Sci Rep. 10:6441. PubMed
  332. Edwards G, et al. 2020. Cell Death Dis. 11:254. PubMed
  333. Nishimura K, et al. 2017. PLoS One. 12:e0170568. PubMed
  334. Roselló-Busquets C, et al. 2020. Front Mol Neurosci. 13:56. PubMed
  335. Wang X, et al. 2019. Front Neurosci. 1.324305556. PubMed
  336. Lasman L, et al. 2020. Genes Dev. 34:1373. PubMed
  337. Wong HS, et al. 2021. Cell. . PubMed
  338. Kim JW, et al. 2020. Cell Stem Cell. 27(4):633-645.e7. PubMed
  339. Evsen L, et al. 2020. Development. 147:00:00. PubMed
  340. Huang YA, et al. 2020. J Cell Sci. 133:00:00. PubMed
  341. Levin G, et al. 2020. Front Bioeng Biotechnol. 0.663888889. PubMed
  342. Seo HH, et al. 2020. Emerg Microbes Infect. 1.724305556. PubMed
  343. Laura Kerosuo, Marianne E. Bronner 2016. Cell Rep. 17:2648-2659. PubMed
  344. George L, et al. 2016. Dev Biol. 413:70-85. PubMed
  345. Ferletta M, et al. 2011. Int J Cancer. 129:45-60. PubMed
  346. Ha GH, et al. 2022. Aging (Albany NY). 14:. PubMed
  347. Meyer Zu Reckendorf S, et al. 2022. J Neurosci. 42:2474. PubMed
  348. van Niekerk EA, et al. 2022. Cell Rep Methods. 2:100255. PubMed
  349. Nouri P, et al. 2022. Cells. 11:. PubMed
  350. Amo-Aparicio J, et al. 2021. Theranostics. 11:9805. PubMed
  351. Fagerlund I, et al. 2021. Cells. 11:. PubMed
  352. Petrovic A, et al. 2022. Int J Mol Sci. 23:. PubMed
  353. Colombo S, et al. 2022. Development. 149:. PubMed
  354. Sidoli M, et al. 2021. J Neurosci. 41:4536. PubMed
  355. Simone R, et al. 2021. Nature. 594:117. PubMed
  356. Li A, et al. 2021. STAR Protoc. 2:100580. PubMed
  357. Osuka S, et al. 2021. J Clin Invest. 131: . PubMed
  358. Banal C, et al. 2020. Stem Cell Research. 72.78888889. PubMed
  359. Zhao J, et al. 2020. Aging (Albany NY). 12:5590. PubMed
  360. Themeli M, et al. 2020. Stem Cell Reports. 14:300. PubMed
  361. Ding D, et al. 2020. J Otol. 15:36. PubMed
  362. Ilouz R et al. 2017. eLife. 6 pii: e17681. PubMed
  363. Kwart D et al. 2019. Neuron. 104(2):256-270 . PubMed
  364. Di Bella DJ, et al. 2019. Cell Rep. 28:2264. PubMed
  365. Velychko S et al. 2019. Cell reports. 27(1):30-39 . PubMed
  366. Kim J, et al. 2018. Development. 145. PubMed
  367. Yang T et al. 2018. Cell reports. 24(10):2694-2708 . PubMed
  368. Cheng LS, et al. 2017. Pediatr Res. 81:838. PubMed
  369. Augé E, et al. 2018. Sci Rep. 8:13525. PubMed
  370. Shin BC et al. 2018. The Journal of Neuroscience. 38(44):9579-9599 . PubMed
  371. Cárdenas A et al. 2018. Cell. 174(3):590-606 . PubMed
  372. Goffena J, et al. 2018. Nat Commun. 9:889. PubMed
  373. Ogawa Y, et al. 2017. PLoS One. 12(6):e0178978. PubMed
  374. Wirt S, et al. 2010. J Cell Biol. 191:809-825. PubMed
  375. Wang Q, et al. 2016. Sci Rep. 6:19003. PubMed
  376. Petracca Y, et al. 2016. Development. 143: 880 - 891. PubMed
  377. Lalli M, et al. 2016. Hum Mol Genet. 25: 1294-1306. PubMed
  378. Thakurela S, et al. 2016. Sci Rep. 6: 25828. PubMed
  379. Bedogni F, et al. 2016. Cereb Cortex. 26: 2517 - 2529. PubMed
  380. Landegger L, et al. 2017. Nat Biotechnol. 35:280-284. PubMed
  381. Pournasr B, et al. 2020. Stem Cell Res. 48:101953. PubMed
  382. Trapecar M, et al. 2021. Sci Adv. 7:00. PubMed
  383. Smith KE, et al. 2020. Journal of Neuroscience Research. 99(2):679-698. PubMed
  384. Isaja L, et al. 2021. Stem Cell Research. 53:102325. PubMed
  385. Elsayed AK, et al. 2021. Stem Cell Research. 56:102500. PubMed
  386. Bargagna-Mohan P, et al. 2020. J Neurosci Res. . PubMed
  387. Lee N, et al. 2021. Biochem Biophys Rep. 100973:26. PubMed
  388. Zheng Z, et al. 2021. Cell Biol Toxicol. Online ahead of prin. PubMed
  389. Lim SH, et al. 2020. J Cell Sci. . PubMed
  390. Salti A, et al. 2021. Cells. 10:. PubMed
  391. Araki R, et al. 2021. Heliyon. 7:e08071. PubMed
  392. Ye E, et al. 2022. Int J Oncol. 60:. PubMed
  393. Taïb S, et al. 2022. Elife. 11:. PubMed
  394. Bérenger-Currias NM, et al. 2022. J Tissue Eng. 13:20417314221103042. PubMed
  395. Chau KF, et al. 2018. Elife. 19:E663. PubMed
  396. Sun S et al. 2018. Cell. 174(5):1247-1263 . PubMed
  397. Yi‐Lan Weng et al. 2018. Neuron. 97(2):313-325 . PubMed
  398. Bachmann SO, et al. 2019. Transl Psychiatry. 9:29. PubMed
  399. Sabo JK, et al. 2017. Ann Neurol. 81:560. PubMed
  400. Gao L, et al. 2019. Front Cell Neurosci. 13:316. PubMed
  401. Shao Q et al. 2019. PLoS One. 14(6):e0218811 . PubMed
  402. Mohlin S, et al. 2019. EMBO Mol Med. 11:e10058. PubMed
  403. Ibañez Rodriguez MP et al. 2018. The Journal of comparative neurology. 526(15):2462-2481 . PubMed
  404. Duan RS, et al. 2018. Cell Death Differ. 25:1598. PubMed
  405. Pollen AA, et al. 2019. Cell. 176:743. PubMed
  406. Corman A, et al. 2019. Cell Chem Biol. 26:235. PubMed
  407. Molotkov A et al. 2017. Developmental cell. 41(5):511-526 . PubMed
  408. Yang C, et al. 2020. Neuron. 105:276. PubMed
  409. Marchetta P, et al. 2020. Front Aging Neurosci. 12:83. PubMed
  410. Urciuolo A, et al. 2020. Nat Biomed Eng. 4:901. PubMed
  411. Sadick JS, et al. 2020. Ann Biomed Eng. 48:2218. PubMed
  412. Lecomte A, et al. 2020. Adv Biosyst. e2000114:4. PubMed
  413. Wang L, et al. 2020. Nat Commun. 3.2625. PubMed
  414. Sheehan CJ, et al. 2020. Development. 147:00:00. PubMed
  415. Zabolocki M, et al. 2020. Nat Commun. 4.3125. PubMed
  416. Liu R, et al. 2021. Oncol Lett. 21:06. PubMed
  417. Zhang X, et al. 2020. Sci Adv. 6:00. PubMed
  418. Sadick J, et al. 2016. Sci Rep. 6: 33999. PubMed
  419. Guo S, Du Y, Liu X 2016. Nat Commun. 7:12230. PubMed
  420. Kushwaha R, et al. 2016. Stem Cell Reports. 6:772-783. PubMed
  421. Paquet D, et al. 2016. Nature. 533: 125-129. PubMed
  422. Binder Z, et al. 2016. PLoS One. 11: 0150271. PubMed
  423. He H, et al. 2016. J Neurosci. 36: 3079 - 3091. PubMed
  424. Fujiwara N, et al. 2022. Pediatr Surg Int. 39:18. PubMed
  425. Zhu Z, et al. 2022. Aging Cell. 21:e13587. PubMed
  426. Schaeffer J, et al. 2022. Front Cell Dev Biol. 10:917589. PubMed
  427. Li J, et al. 2021. Neural Plast. 2021:4894881. PubMed
  428. Wilmerding A, et al. 2021. Int J Mol Sci. 22:. PubMed
  429. Hu D, et al. 2021. Nat Commun. 12:5305. PubMed
  430. Russo-Savage L, et al. 2020. Neurobiol Aging. 95:69. PubMed
  431. Khong ZJ, et al. 2020. Cell Death Dis. 11:182. PubMed
  432. Pinheiro H, et al. 2018. Front Pharmacol. 0.527083333. PubMed
  433. Ichihara–Tanaka K, et al. 2017. J Histochem Cytochem. 65:513. PubMed
  434. Harrington AJ et al. 2016. eLife. 5 pii: e20059. PubMed
  435. Michael Lerche et al. 2017. Structure (London, England : 1993). 25(8):1175-1186 . PubMed
  436. Larhammar M et al. 2017. eLife. 6 pii: e20725. PubMed
  437. Lavado A et al. 2018. Dev Cell. 47(5):576-591 . PubMed
  438. Freeman S et al. 2019. EMBO Rep. 20(9):e47097 . PubMed
  439. Kaur T, et al. 2019. Front Neurosci. 13:620. PubMed
  440. Nash B et al. 2019. eNeuro. 6(4) pii: ENEURO. PubMed
  441. Sarkar C, et al. 2019. Autophagy. N/A. PubMed
  442. Tramarin M, et al. 2018. Hum Mol Genet. 27:2052. PubMed
  443. Xue J, et al. 2017. ACS Appl Mater Interfaces. 9:12299. PubMed
  444. Toda T, et al. 2017. Cell Stem Cell. 21:618. PubMed
  445. Amaral JD, et al. 2019. Front Chem. 7:15. PubMed
  446. Wang XW, et al. 2018. Cell Rep. 24:2540. PubMed
  447. Tavano S et al. 2018. Neuron. 97(6):1299-1314 . PubMed
  448. Luisier R, et al. 2018. Nat Commun. 8:6458. PubMed
  449. Pinto M, et al. 2016. J Cell Biol. 212: 789 - 801. PubMed
  450. Okamoto M, et al. 2016. Nat Commun. 7: 11349. PubMed
  451. Liu X, et al. 2016. Nat Commun. 7:11508. PubMed
  452. Grandi FC, et al. 2020. Front Mol Neurosci. 0.599305556. PubMed
  453. Ewan EE, et al. 2021. Sci Rep. 0.718055556. PubMed
  454. Brievac D, et al. 2020. Journal of Neurochemistry. 157(3):666-683. PubMed
  455. Hu Z, et al. 2020. Cell Rep. 107657:31. PubMed
  456. de Matos AM, et al. 2020. J Med Chem. 63:11663. PubMed
  457. Calamini B, et al. 2021. Dis Model Mech. 14:. PubMed
  458. Gandhi S, et al. 2021. Development. 148:. PubMed
  459. Stern S, et al. 2021. Neuron. 109:3436. PubMed
  460. Nath M, et al. 2022. Eneuro. 9:. PubMed
  461. Lehtonen Ŝ et al. 2018. Stem cell research. 30:96-99 . PubMed
  462. Qiang L et al. 2018. Current biology : CB. 28(13):2181-2189 . PubMed
  463. Hor JH, et al. 2018. Cell Death Dis. 9:1100. PubMed
  464. Gupta S et al. 2017. Journal of neurochemistry. 145(3):188-203 . PubMed
  465. Howlett EH, et al. 2017. Hum Mol Genet. 26:4340. PubMed
  466. Zunke F et al. 2017. Neuron. 97(1):92-107 . PubMed
  467. Fernandes KA, et al. 2018. Exp Eye Res. 171:54. PubMed
  468. Linkous A et al. 2019. Cell reports. 26(12):3203-3211 . PubMed
  469. Pronin A, et al. 2019. Front Mol Neurosci. 12:36. PubMed
  470. Meijer M et al. 2019. Cell Rep. 27(7):2199-2211 . PubMed
  471. Lin CI et al. 2019. eNeuro. 6(4) pii: ENEURO. PubMed
  472. Auboyer L et al. 2019. Stem Cell Res. 1723:41:00 . PubMed
  473. Kurtenbach S et al. 2017. PloS one. 12(11):e0187576 . PubMed
  474. Yu M et al. 2017. Cell research. 27(12):1441-1465 . PubMed
  475. Huh CJ et al. 2016. eLife. 5 pii: e18648. PubMed
  476. Li J, et al. 2018. Neural Plast. 2018:6890613. PubMed
  477. Chen YT, et al. 2019. Stem Cell Res Ther. 0.6875. PubMed
  478. Syal C, et al. 2020. Theranostics. 10:6337. PubMed
  479. Xu PF, et al. 2021. Nature Communications. 12(1):3277. PubMed
  480. Anderson EM, et al. 2021. Addiction Biology. :e13060. PubMed
  481. Lin NH, et al. 2021. The FASEB Journal. 35(5):e21614. PubMed
  482. Leibinger M, et al. 2021. Nature Communications. 12(1):391. PubMed
  483. Huang S, et al. 2020. Cell Rep. 33:108394. PubMed
  484. Rubio A, et al. 2016. Sci Rep. 6:37540. PubMed
  485. Intoh A, et al. 2016. Hum Mol Genet. 10.1093/hmg/ddw053. PubMed
  486. Sancho-Martinez I, et al. 2016. Nat Commun. 7:10743. PubMed
  487. Jouhilahti E, et al. 2008. J Histochem Cytochem. 56:1113-1119. PubMed
  488. Contreras E, et al. 2022. Cell Tissue Res. :. PubMed
  489. Sluysmans S, et al. 2021. Mol Biol Cell. 32:ar34. PubMed
  490. Ma C, et al. 2022. Int J Mol Med. 50:. PubMed
  491. Khan M, et al. 2021. Cell. 184:5932. PubMed
  492. Gilliam EA, et al. 2020. American Journal of Physiology-Gastrointestinal and Liver Physiology. 319(2):G261-G279.. PubMed
  493. Dionisi C, et al. 2020. Sci Rep. 10:7752. PubMed
  494. Lindsay CD, et al. 2019. Acta Biomater. 95:225. PubMed
  495. Makdissy N, et al. 2018. Stem Cell Res Ther. 0.466666667. PubMed
  496. Mettang M, et al. 2018. FASEB J. 32:1916. PubMed
  497. Chen X et al. 2017. Developmental cell. 43(5):563-576 . PubMed
  498. Hegarty DM, et al. 2017. J Comp Neurol. 525:2019. PubMed
  499. Tsuboi M, et al. 2018. Dev Cell. 47:758. PubMed
  500. Sharma N et al. 2019. Neuron. 102(2):390-406 . PubMed
  501. Mo J, et al. 2017. Invest Ophthalmol Vis Sci. 58:137. PubMed
  502. Rhee HJ et al. 2019. Cell Rep. 27(7):2212-2228 . PubMed
  503. Makar T, et al. 2018. Stem Cell Res Ther. 9:127. PubMed
  504. Debadrita Bhattacharya et al. 2018. eLife. 7 pii: e40556. PubMed
  505. Zahr SK et al. 2018. Neuron. 97(3):520-537 . PubMed
  506. Kim YJ, et al. 2018. Neuron. 100:1180. PubMed
  507. Xue Y, et al. 2016. Nat Neurosci. 19: 807-15. PubMed
  508. Muscat A, et al. 2016. Clin Cancer Res. 22: 3560 - 3570. PubMed
  509. Sandor C, et al. 2017. Hum Mol Genet. 10.1093/hmg/ddw412. PubMed
  510. Ingersoll MA, et al. 2020. Sci Adv. 6:00. PubMed
  511. Jiang B, et al. 2020. Sci Adv. 6:00. PubMed
  512. Barbuti PA, et al. 2020. Cells. 9:00. PubMed
  513. Vila-Cejudo M, et al. 2018. Journal of Assisted Reproduction and Genetics. 36(1):99-111. PubMed
  514. Koinuma S, et al. 2020. Journal of Neurochemistry. 157(4):1196-1206. PubMed
  515. Dementyeva EV, et al. 2021. Stem Cell Research. 53:102344. PubMed
  516. Han JS, et al. 2020. Proc Natl Acad Sci U S A. 23073:117. PubMed
  517. Gupta S, et al. 2021. STAR Protoc. 100319:2. PubMed
  518. Hertzano R, et al. 2020. Laryngoscope. . PubMed
  519. Borys BS, et al. 2021. Stem Cell Res Ther. 12:55. PubMed
  520. Little JN, et al. 2021. J Neurosci. 41:3344. PubMed
  521. Sanchez CG, et al. 2021. Commun Biol. 4:736. PubMed
  522. Wang L, et al. 2021. Nat Med. 27:1600. PubMed
  523. Sepehrimanesh M, et al. 2021. STAR Protoc. 2:100917. PubMed
  524. Barbuti PA, et al. 2021. Sci Rep. 11:21946. PubMed
  525. Meng X, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  526. Argolo DS, et al. 2022. Int J Tryptophan Res. 15:11786469211069946. PubMed
  527. Li Y, et al. 2022. J Cell Biol. 221:. PubMed
  528. Yamamoto Y, et al. 2022. Life Sci Alliance. 5:. PubMed
  529. Chen J, et al. 2021. Int J Mol Sci. 23:. PubMed
  530. Zhang H, et al. 2022. Elife. 11:. PubMed
  531. Tang J, et al. 2022. Antioxidants (Basel). 11:. PubMed
  532. Flaherty E,et al. 2017. NPJ Schizophr.. 10.1038/s41537-017-0033-5. PubMed
  533. Ryan T, et al. 2018. Nat Commun. 9:817. PubMed
  534. Moon KH et al. 2018. Developmental cell. 44(1):13-28 . PubMed
  535. Xu Z, et al. 2019. Front Neurosci. 12:970. PubMed
  536. Joanna Ruth Appel et al. 2018. The Journal of Neuroscience. 38(26):5949-5968 . PubMed
  537. Vyas P, et al. 2019. Sci Rep. 9:5549. PubMed
  538. Zhang N, et al. 2019. Adv Sci (Weinh). 6:1800808. PubMed
  539. Singh K, et al. 2018. Front Mol Neurosci. 11:30. PubMed
  540. Friocourt F et al. 2019. The Journal of comparative neurology. 527(12):2009-2029 . PubMed
  541. Weng YL, et al. 2017. Neuron. 94:337. PubMed
  542. Espuny‐Camacho I et al. 2017. Neuron. 93(5):1066-1081 . PubMed
  543. Park JH, et al. 2018. Mol Cell Biol. 38:e00217. PubMed
  544. Ozaki K, et al. 2019. Invest Ophthalmol Vis Sci. 60:4151. PubMed
  545. Llères D, et al. 2019. Genome Biol. 1.022222222. PubMed
  546. Dourado NS, et al. 2020. Front Aging Neurosci. 12:119. PubMed
  547. Götzl JK, et al. 2018. Mol Neurodegener. 13:48. PubMed
  548. Cuddy LK, et al. 2021. STAR Protoc. 100340:2. PubMed
  549. Matern MS, et al. 2020. Development. :147. PubMed
  550. Nikulina E, et al. 2020. FEBS Lett. 1389:594. PubMed
  551. Ghita L, et al. 2021. Journal of Neuroscience Research. :. PubMed
  552. Simon DJ, et al. 2021. Developmental Cell. 56(7):976-984.e3. PubMed
  553. Maor-Nof M, et al. 2021. Cell. 184(3):689-708.e20. PubMed
  554. Kraemer BR, et al. 2020. Neuroscience. 453:222-236. PubMed
  555. Schörnig M, et al. 2021. Elife. 10:00. PubMed
  556. Camilieri-Asch V, et al. 2020. Front Neuroanat. 14:560534. PubMed
  557. Durak O, et al. 2016. Nat Neurosci. 19:1477-1488. PubMed
  558. Drobish J, et al. 2016. Toxicol Sci. 154(2):309-319. PubMed
  559. Marchetto M, et al. 2016. Mol Psychiatry. 10.1038/mp.2016.95. PubMed
  560. Wang W, et al. 2016. Nat Commun. 7:10936. PubMed
  561. Tanimoto R, et al. 2016. Sci Rep. 6:22071. PubMed
  562. Reyes RV, et al. 2022. Front Neurosci. 16:908719. PubMed
  563. He B, et al. 2021. J Anat. 239:913. PubMed
  564. Arsic A, et al. 2022. Nat Commun. 13:314. PubMed
  565. Calamini B, et al. 2021. Dis Model Mech. . PubMed
  566. Brown D, et al. 2021. Neurotherapeutics. 18:387. PubMed
  567. Wang M, et al. 2021. Neuron. 109:257. PubMed
  568. Ren J, et al. 2021. Cells. 10:. PubMed
  569. Cui K, et al. 2020. Microsyst Nanoeng. 6:49. PubMed
  570. Stathakos P, et al. 2020. Autophagy. :1. PubMed
  571. Huang YA, et al. 2019. J Neurosci. 39:7408. PubMed
  572. Dang LT, et al. 2020. Front Cell Neurosci. 14:122. PubMed
  573. Sloan SA et al. 2017. Neuron. 95(4):779-790 . PubMed
  574. Shao Q et al. 2017. The Journal of Neuroscience. 37(23):5620-5633 . PubMed
  575. Wu JS et al. 2017. The Journal of comparative neurology. 526(3):425-438 . PubMed
  576. Wu C, et al. 2019. Cell Rep. 26:1143. PubMed
  577. Vassilev V, et al. 2017. Dev Cell. 43:463. PubMed
  578. Kim J, et al. 2017. Histochem Cell Biol. 148:489. PubMed
  579. Thayer JA, et al. 2019. Autophagy. 7:1-14. PubMed
  580. Liu WA, et al. 2018. Genes Dev. 32:763. PubMed
  581. Trajkovic K, et al. 2019. PLoS One. 14:e0211727. PubMed
  582. Oksanen M et al. 2018. Stem cell research. 31:181-185 . PubMed
  583. Johansson E, et al. 2017. Cell Rep. 10.1016/j.celrep.2017.07.049. PubMed
  584. Quintes S, et al. 2016. Nat Neurosci. 10.1038/nn.4321. PubMed
  585. Demais V, et al. 2016. J Neurosci. 36: 8012 - 8025. PubMed
  586. Borromeo M, et al. 2016. Cell Rep. 16:1259-1272. PubMed
  587. Borgs L, et al. 2016. Sci Rep. 6: 33377. PubMed
  588. Enriquez‐Rios V et al. 2017. The Journal of Neuroscience. 37(4):893-905 . PubMed
  589. Shi W, et al. 2017. Nat Neurosci. 10.1038/nn.4519. PubMed
  590. Brann DH, et al. 2020. Sci Adv. 6:00. PubMed
  591. McNeely KC, et al. 2020. Proc Natl Acad Sci U S A. 117:9584. PubMed
  592. Li Y, et al. 2021. Stem Cell Research. 55:102460. PubMed
  593. Hilla AM, et al. 2018. BIO-PROTOCOL. 8(16):e2979. PubMed
  594. Kitajima R, et al. 2020. Stem Cell Res. 101749:44. PubMed
  595. Fouda AY, et al. 2020. Invest Ophthalmol Vis Sci. 51:61. PubMed
  596. Petrovic A, et al. 2021. Front Cell Neurosci. 15:661492. PubMed
  597. Liang D, et al. 2021. Nat Neurosci. 24:941. PubMed
  598. Lautz JD, et al. 2021. Cell Rep. 37:110076. PubMed
  599. De La Rossa A, et al. 2022. Elife. 11:. PubMed
  600. Rabadán MA, et al. 2022. Nat Commun. 13:3340. PubMed
  601. Williams LA, et al. 2022. Mol Ther Nucleic Acids. 29:189. PubMed
  602. Vahsen BF, et al. 2022. Sci Rep. 12:12606. PubMed
  603. Sefiani A, et al. 2022. Sci Rep. 12:13125. PubMed
  604. Tay SH, et al. 2021. Methods Mol Biol. 2549:359. PubMed
  605. Fisher ES, et al. 2022. J Neuroinflammation. 19:266. PubMed
  606. Wu X, et al. 2018. Cell. 172:423. PubMed
  607. Buijsen RAM et al. 2018. Stem cell research. 29:125-128 . PubMed
  608. Miquel‐Serra L et al. 2018. Stem cell research. 24:155-159 . PubMed
  609. Senft AD, et al. 2018. Cell Rep. 24:1977. PubMed
  610. Gao L, et al. 2019. Sci Rep. 9:3462. PubMed
  611. Xu Z, et al. 2018. Development. 145:. PubMed
  612. Christiansen EM, et al. 2018. Cell. 173:792. PubMed
  613. Rich CA, et al. 2018. Glia. 66:2617. PubMed
  614. Heil C, et al. 2019. Open Biol. 9:180145. PubMed
  615. Wanner R, et al. 2019. Front Neurol. 10:310. PubMed
  616. Hickey SL et al. 2019. Cell reports. 27(6):1699-1711 . PubMed
  617. Suarato G, et al. 2017. Biomaterials. 112:176. PubMed
  618. Watanabe Y, et al. 2018. Development. 145. PubMed
  619. Chanda S et al. 2019. Cell Stem Cell. 25(1):103-119 . PubMed
  620. Wu Z, et al. 2019. Neuron. 101:635. PubMed
  621. Bachmann SB, et al. 2019. Cell Rep. 27:3305. PubMed
  622. Kaplan A, et al. 2017. Neuron. 93:1082. PubMed
  623. Tozer S, et al. 2017. Neuron. 93:542. PubMed
  624. Leibinger M et al. 2017. Proceedings of the National Academy of Sciences of the United States of America. 114(27):E5454-E5463 . PubMed
  625. Syc–Mazurek SB, et al. 2018. Cell Death Dis. 1.135416667. PubMed
  626. Kang PH, et al. 2020. Mol Biol Cell. 31:386. PubMed
  627. Tehrani S, et al. 2018. Sci Rep. 8:4453. PubMed
  628. Russo R, et al. 2018. Cell Death Dis. 1.05625. PubMed
  629. Suenkel C, et al. 2020. Cell Reports. 30(7):2170-2179. PubMed
  630. Peitz M, et al. 2020. STAR Protoc. 1:100038. PubMed
  631. Calado SM, et al. 2021. Stem Cell Research. 55:102462. PubMed
  632. Bieler M, et al. 2021. Journal of Comparative Neurology. 529(12):3194-3205. PubMed
  633. Kondo N, et al. 2020. Cancers (Basel). 12:00. PubMed
  634. Friocourt F, et al. 2017. Sci Rep. 7:37569. PubMed
  635. Fimiani C, et al. 2016. Sci Rep. 6:39311. PubMed
  636. Damiani D, et al. 2016. Nat Commun. 7:13509. PubMed
  637. Hegazy A, et al. 2016. J Biol Chem. 291: 21496 - 21509. PubMed
  638. Maison S, Liberman L, Liverman M 2016. eNeuro. 3: ENEURO.0207-16.2016. PubMed
  639. Edmondson R, Adock A, Yang L 2016. PLoS One. 11: 0158116. PubMed
  640. Jablonski K, et al. 2016. Stem Cell Reports. 8: 1119-1127. PubMed
  641. Rraklli V, et al. 2016. Stem Cell Res. 16:1-9. PubMed
  642. Kizuka Y, et al. 2016. Biochem J. 473: 21 - 30. PubMed
  643. Kim K, et al. 2013. J Cell Biol. 200:443-458. PubMed
  644. Cesca F, et al. 2012. Cell Death Differ. 19:194-208. PubMed
  645. Rantanen LM, et al. 2022. Cells. 11:. PubMed
  646. Hamity MV, et al. 2022. Invest Ophthalmol Vis Sci. 63:38. PubMed
  647. Lam AN, et al. 2021. Data Brief. 35:106897. PubMed
  648. Cui K, et al. 2022. Cell Regen. 11:7. PubMed
  649. Zhao D, et al. 2021. Cell Death Differ. 28:337. PubMed
  650. Schenk MS, et al. 2021. Transl Vis Sci Technol. 10:22. PubMed
  651. Dong Y, et al. 2021. STAR Protoc. 2:100853. PubMed
  652. Yao H, et al. 2020. Sci Rep. 10:17445. PubMed
  653. Matthies D, et al. 2020. Sci Rep. 10:11953. PubMed
  654. Hattori Y, et al. 2020. Nat Commun. 11:1631. PubMed
  655. Duncan DS, et al. 2018. Front Neurosci. 0.9875. PubMed
  656. Welsbie DS et al. 2017. Neuron. 94(6):1142-1154 . PubMed
  657. Belle M et al. 2017. Cell. 169(1):161-173 . PubMed
  658. Walker LJ et al. 2017. eLife. 6 pii: e22540. PubMed
  659. Mura M et al. 2019. Stem Cell Res. 1727:31:00 . PubMed
  660. Gao F et al. 2019. Mol Cell. 75(5):891-904 . PubMed
  661. Kurabayashi N, et al. 2018. Development. 145. PubMed
  662. Miesfeld JB et al. 2017. Gene expression patterns : GEP. 27:114-121 . PubMed
  663. Calatayud C, et al. 2019. Sci Rep. 9:6811. PubMed
  664. Pai EL et al. 2019. Cell reports. 26(5):1157-1173 . PubMed
  665. Teng X, et al. 2018. Thyroid. 28:667. PubMed
  666. Sun L, et al. 2017. Oncotarget. 8:40065. PubMed
  667. Spitalieri P, et al. 2018. Front Physiol. 9:967. PubMed
  668. Erin Frey et al. 2018. eNeuro. 5(3) pii: ENEURO. PubMed
  669. Mura M et al. 2018. Stem cell research. 29:157-161 . PubMed
  670. Flores-Otero J, et al. 2007. J Neurosci. 27:14023-14034. PubMed
  671. Wang L, Hou S, Han Y 2016. Nat Neurosci. 19: 888-896. PubMed
  672. Roese-Koerner B, et al. 2016. Stem Cell Reports. 7:207-219. PubMed
  673. Choi R, et al. 2020. Laryngoscope Investig Otolaryngol. 0.885416667. PubMed
  674. Ng AQE, et al. 2020. Cell Reports. 30(5):1434-1446.e7. PubMed
  675. Hawkins FJ, et al. 2020. Cell Stem Cell. 28(1):79-95.e8. PubMed
  676. Arber C, et al. 2021. Cell Reports. 34(2):108615. PubMed
  677. Zhang X, et al. 2021. Cell Reports. 34(11):108830. PubMed
  678. Czeisler C, et al. 2016. Journal of Comparative Neurology. 524(17):3485-3502. PubMed
  679. Abreu CA, et al. 2021. Journal of Neurochemistry. 158(3):694-709. PubMed
  680. Doucet-O'Hare TT, et al. 2021. Sci Rep. 11:12893. PubMed
  681. Gandhi S, et al. 2021. Development. 148:dev193565. PubMed
  682. Ketschek A, et al. 2021. J Neurosci. 41:6637. PubMed
  683. Park SH, et al. 2021. Biochem Pharmacol. 188:114520. PubMed
  684. Oksdath Mansilla M, et al. 2021. BMC Biomed Eng. 3:6. PubMed
  685. Liu P, et al. 2017. Stem Cell Rep. 10.1016/j.stemcr.2017.05.007. PubMed
  686. Sommer A et al. 2018. Cell stem cell. 23(1):123-131 . PubMed
  687. Mains RE et al. 2018. Endocrinology. 159(7):2621-2639 . PubMed
  688. Kelly SM et al. 2018. Neuron. 99(2):345-361 . PubMed
  689. Han S, et al. 2018. Development. 145:. PubMed
  690. Friedl RM, et al. 2019. Dis Model Mech. 0.5. PubMed
  691. Khayati K, et al. 2017. FASEB J. 31:598. PubMed
  692. Comai G et al. 2019. Elife. 8 pii: e47460. PubMed
  693. Lee SG et al. 2018. Stem Cell Res. 31:197-200 . PubMed
  694. Zhu J et al. 2017. Cell stem cell. 20(3):374-384 . PubMed
  695. Gouti M, et al. 2017. Dev Cell. 41:243. PubMed
  696. Levin E et al. 2017. Scientific reports. 7(1):643 . PubMed
  697. Tokuyama MA, et al. 2018. Dev Biol. 433:287. PubMed
  698. Xie Y, et al. 2019. RNA Biol. 0.723611111. PubMed
  699. Yang D, et al. 2019. Elife. 8:e49249. PubMed
  700. Heinrich A, et al. 2020. Cell Rep. 31:107513. PubMed
  701. Park S, et al. 2020. PLoS Biol. 18:e3000296. PubMed
  702. Pappa S, et al. 2019. Proc Natl Acad Sci U S A. 116:19464. PubMed
  703. Marquardt LM, et al. 2020. Sci Adv. 6:eaaz1039. PubMed
  704. Bouma MJ, et al. 2019. Stem Cell Research. 41:101654. PubMed
  705. Rebs S, et al. 2021. Stem Cell Research. 53:102263. PubMed
  706. Gao T, et al. 2021. JCI Insight. 6(10):. PubMed
  707. Liu W, et al. 2020. J Exp Med. 217:00:00. PubMed
  708. Franco A, et al. 2020. Elife. 9:00. PubMed
  709. Chen W, et al. 2017. eNeuro. 3(6). PubMed
  710. Teresa Rivera, Candy Haggblom, Sandro Cosconati 2016. Nat Struct Mol Biol. 24:30-39. PubMed
  711. Jager P, et al. 2016. Nat Commun. 7:13579. PubMed
  712. Zeltner N, et al. 2016. Nat Med. 22:1421-1427. PubMed
  713. Gaitán-Peñas H, et al. 2016. Biophys J. 111:1429-1443. PubMed
  714. Zalfa C, et al. 2016. Cell Death Dis. 7:e2331. PubMed
  715. Li S, et al. 2016. Sci Rep. 6:29514. PubMed
  716. Mita T, et al. 2016. J Biol Chem. 291: 4955 - 4965. PubMed
  717. Xu X, et al. 2022. Biology (Basel). 11:. PubMed
  718. Namchaiw P, et al. 2022. PLoS One. 17:e0273458. PubMed
  719. Wu C, et al. 2022. J Hum Genet. :. PubMed
  720. Wilmerding A, et al. 2022. Neoplasia. 24:120. PubMed
  721. Yang Y, et al. 2022. Nucleic Acids Res. 50:191. PubMed
  722. Hilton BJ, et al. 2021. Neuron. S0896-6273:00775-3. PubMed
  723. Bassil R, et al. 2021. Nat Commun. 12:5220. PubMed
  724. Vaes N, et al. 2021. EMBO Rep. 22:e51913. PubMed
  725. Jia L, et al. 2018. Mol Neurobiol. 55:9089. PubMed
  726. Sun W, et al. 2020. J Clin Invest. 130:345. PubMed
  727. Baek C, et al. 2018. PLoS Biol. 16:e2004162. PubMed
  728. Miyake S et al. 2015. Cell death & disease. 6:e1638 . PubMed
  729. Wang L et al. 2017. The Journal of comparative neurology. 525(13):2915-2928 . PubMed
  730. Stratton JA et al. 2017. eNeuro. 4(3) pii: ENEURO. PubMed
  731. Norsworthy MW et al. 2017. Neuron. 94(6):1112-1120 . PubMed
  732. Brekk OR et al. 2018. Molecular and cellular neurosciences. 95:1-12 . PubMed
  733. Mura M et al. 2019. Stem cell research. 1726:16:00 . PubMed
  734. Jung JS, et al. 2019. J Neurosci. 39:6425. PubMed
  735. Fan D et al. 2019. Elife. 8 pii: e49226. PubMed
  736. Sarah E Pease‐Raissi et al. 2017. Neuron. 96(2):373-386 . PubMed
  737. Sorrells SF, et al. 2019. Nat Commun. 10:2748. PubMed
  738. Lee J, et al. 2018. Invest Ophthalmol Vis Sci. 59:3531. PubMed
  739. Alexander JM et al. 2019. Elife. 8 pii: e41769. PubMed
  740. Hu D, et al. 2019. Acta Neuropathol. 137:939. PubMed
  741. Acosta S, et al. 2018. Genesis. 56:e23212. PubMed
  742. Stallings NR, et al. 2018. Sci Signal. 11:522. PubMed
  743. Diacou R et al. 2018. Cell reports. 25(9):2510-2523 . PubMed
  744. Liu Y et al. 2018. Cell stem cell. 23(5):758-771 . PubMed
  745. Umegaki Y et al. 2018. The Journal of Neuroscience. 38(21):4985-4995 . PubMed
  746. Urrea L, et al. 2018. Mol Neurobiol. 15:1630. PubMed
  747. Dudok J, et al. 2016. Neurosci Res. S0168-0102(16)00002-X. PubMed
  748. Rooney G, et al. 2016. J Neurosci. 36: 142 - 152.. PubMed
  749. Takeo Y, et al. 2016. Sci Rep. 6: 25180. PubMed
  750. Okamoto-Uchida Y, et al. 2016. Sci Rep. 6:37697. PubMed
  751. Wang H, et al. 2017. J Neurochem. 141:347. PubMed
  752. Arber C, et al. 2020. Mol Psychiatry. 25:2919. PubMed
  753. Dementyeva EV, et al. 2021. Stem Cell Research. 53:102348. PubMed
  754. Hung C, et al. 2021. Cell Reports. 35(11):109259. PubMed
  755. Cartoni R, et al. 2016. Neuron. 92(6):1294-1307. PubMed
  756. Schoger E, et al. 2021. Stem Cell Research. 55:102473. PubMed
  757. Valdez C, et al. 2020. Hum Mol Genet. 716:29. PubMed
  758. Tolomeo AM, et al. 2021. Front Cell Neurosci. 602888:15. PubMed
  759. Ornaghi F, et al. 2020. Neurobiol Dis. 134:104667. PubMed
  760. Gangoso E, et al. 2021. Cell. 184:2454. PubMed
  761. Sun Z, et al. 2021. Aging (Albany NY). 13:12587. PubMed
  762. Chen Y, et al. 2021. Nat Methods. 18:528. PubMed
  763. Cast TP, et al. 2021. J Neurosci. 41:392. PubMed
  764. Satoh M, et al. 2021. Int J Mol Sci. 22:. PubMed
  765. Eriksen AZ, et al. 2022. STAR Protoc. 3:101383. PubMed
  766. Kempfle JS, et al. 2021. Front Cell Neurosci. 15:666706. PubMed
  767. Guan Y, et al. 2021. Nat Commun. 12:5078. PubMed
  768. Yao X, et al. 2022. Nat Commun. 13:3883. PubMed
  769. Tasdemir-Yilmaz OE, et al. 2021. Dev Cell. 56:2516. PubMed
  770. Hackelberg S, et al. 2017. PLoS One. 10.1371/journal.pone.0180427. PubMed
  771. Stepp MA, et al. 2018. Exp Eye Res. 10:113. PubMed
  772. Merten N et al. 2018. Cell chemical biology. 25(6):775-786 . PubMed
  773. Tandon R et al. 2018. Stem cell research. 33:120-124 . PubMed
  774. Kaur T et al. 2018. The Journal of comparative neurology. 526(5):824-835 . PubMed
  775. Lang C et al. 2019. Cell stem cell. 24(1):93-106 . PubMed
  776. Stylianou N, et al. 2019. Oncogene. 38:913. PubMed
  777. Tiihonen J, et al. 2019. Nat Commun. 10:3933. PubMed
  778. Park KK et al. 2017. The Journal of comparative neurology. 525(2):380-388 . PubMed
  779. Chang CH, et al. 2019. Dev Cell. 48:184. PubMed
  780. Hertz NT et al. 2019. Neuron. 103(3):412-422 . PubMed
  781. Angelim MKSC et al. 2018. Glia. 66(11):2470-2486 . PubMed
  782. Wu J et al. 2017. Cell. 168(3):473-486 . PubMed
  783. Ma S et al. 2017. Developmental cell. 41(4):366-381 . PubMed
  784. Sevilla A et al. 2017. Stem Cell Res. 25:217-220 . PubMed
  785. Crouch EE et al. 2015. The Journal of Neuroscience. 35(11):4528-39 . PubMed
  786. Liu Z, et al. 2017. Stem Cells Dev. 26:177. PubMed
  787. Maslon MM, et al. 2019. EMBO J. 38:e101244. PubMed
  788. Steevens AR, et al. 2019. Development. 146:dev170522. PubMed
  789. Liu W, et al. 2019. Invest Ophthalmol Vis Sci. 60:965. PubMed
  790. Lee JH, et al. 2019. Aging (Albany NY). 11:11541. PubMed
  791. Peng XQ, et al. 2020. Front Cell Neurosci. 0.674305556. PubMed
  792. Cai T, et al. 2021. Cell Reports. 36(2):109337. PubMed
  793. van Helden RWJ, et al. 2021. Stem Cell Research. 53:102374. PubMed
  794. Calado SM, et al. 2021. Stem Cell Research. 53:102302. PubMed
  795. Sepehrimanesh M, et al. 2020. American Journal of Physiology-Cell Physiology. 319(4):C771-C780. PubMed
  796. Li C, et al. 2020. eLife. 9:00. PubMed
  797. Fame R, et al. 2016. J Neurosci. 36: 6403 - 6419. PubMed
  798. Long K, et al. 2016. Nat Commun. 7:10354. PubMed
  799. Vicentini FA, et al. 2021. Microbiome. 9:210. PubMed
  800. Díaz-García S, et al. 2021. Acta Neuropathol. 142:985. PubMed
  801. Harbuzariu A, et al. 2022. iScience. 25:104407. PubMed
  802. Karpinski BA, et al. 2022. Dis Model Mech. 15:. PubMed
  803. Hindman HB, et al. 2019. Exp Eye Res. 181:49. PubMed
  804. Aravamudhan P, et al. 2020. PLoS Pathog. 16:e1008380. PubMed
  805. Medeiros CS, et al. 2018. J Refract Surg. 34:790. PubMed
  806. Romer–Seibert JS, et al. 2019. FASEB J. 33:3291. PubMed
  807. Cotton JL et al. 2017. Developmental cell. 43(1):35-47 . PubMed
  808. Lin B et al. 2017. Cell stem cell. 21(6):761-774 . PubMed
  809. Richard E et al. 2018. Stem cell research. 29:143-147 . PubMed
  810. Kano M, et al. 2019. Endocrinology. 160:1701. PubMed
  811. Schreurs RRCE, et al. 2019. Immunity. 50:462. PubMed
  812. Ioannou MS et al. 2019. Curr Protoc Cell Biol. 84(1):e95 . PubMed
  813. Poulopoulos A, et al. 2019. Nature. 565:356. PubMed
  814. Sun Z, et al. 2019. Nat Commun. 10:3892. PubMed
  815. Ding D, et al. 2018. J Otol. 13:115. PubMed
  816. Fan L et al. 2018. eLife. 7 pii: e35242. PubMed
  817. Amrita Pathak et al. 2018. Developmental cell. 46(3):376-387 . PubMed
  818. Marlier Q et al. 2018. Cell Death Discov. 4:43 . PubMed
RRID
AB_2313773 (BioLegend Cat. No. 801213)
AB_2313773 (BioLegend Cat. No. 801201)
AB_2313773 (BioLegend Cat. No. 801202)
Disclaimer

Covered by US patents 5,675,063 and 7,429,487. Sold under license from Epitomics.

Antigen Details

Structure
Tubulin β 3 is a 450 amino acid protein with a molecular mass of ~50 kD.
Distribution

Tissue distribution: central and peripheral nervous system.
Cellular distribution: cytosol, cytoskeleton and nucleus.

Function
Tubulin β 3 is the major constituent of microtubules, and plays a critical role in proper axon guidance and maintenance.
Interaction
Alpha tubulin, kinesin and dynein.
Cell Type
Mature Neurons, Neural Stem Cells
Biology Area
Cell Biology, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
Microtubules
Antigen References

1. Zhao X, et al. 2017. Med Sci Monit. 22: 3915.
2. Lebok P, et al. 2016. Oncol Lett. 11(3):1987.
3. Du J, et al. 2015. BMC Cancer. 15:536. PubMed
4. Rogue DM., et al. 2013. Clin Exp Metastasis. 31(1): 101.
5. Ploussard G, et al. 2010. Cancer Res. 70(22):9253. PubMed

Gene ID
10381 View all products for this Gene ID
UniProt
View information about Tubulin beta-3 on UniProt.org

Related FAQs

If an antibody clone has been previously successfully used in IBEX in one fluorescent format, will other antibody formats work as well?

It’s likely that other fluorophore conjugates to the same antibody clone will also be compatible with IBEX using the same sample fixation procedure. Ultimately a directly conjugated antibody’s utility in fluorescent imaging and IBEX may be specific to the sample and microscope being used in the experiment. Some antibody clone conjugates may perform better than others due to performance differences in non-specific binding, fluorophore brightness, and other biochemical properties unique to that conjugate.

Will antibodies my lab is already using for fluorescent or chromogenic IHC work in IBEX?

Fundamentally, IBEX as a technique that works much in the same way as single antibody panels or single marker IF/IHC. If you’re already successfully using an antibody clone on a sample of interest, it is likely that clone will have utility in IBEX. It is expected some optimization and testing of different antibody fluorophore conjugates will be required to find a suitable format; however, legacy microscopy techniques like chromogenic IHC on fixed or frozen tissue is an excellent place to start looking for useful antibodies.

Are other fluorophores compatible with IBEX?

Over 18 fluorescent formats have been screened for use in IBEX, however, it is likely that other fluorophores are able to be rapidly bleached in IBEX. If a fluorophore format is already suitable for your imaging platform it can be tested for compatibility in IBEX.

The same antibody works in one tissue type but not another. What is happening?

Differences in tissue properties may impact both the ability of an antibody to bind its target specifically and impact the ability of a specific fluorophore conjugate to overcome the background fluorescent signal in a given tissue. Secondary stains, as well as testing multiple fluorescent conjugates of the same clone, may help to troubleshoot challenging targets or tissues. Using a reference control tissue may also give confidence in the specificity of your staining.

How can I be sure the staining I’m seeing in my tissue is real?

In general, best practices for validating an antibody in traditional chromogenic or fluorescent IHC are applicable to IBEX. Please reference the Nature Methods review on antibody based multiplexed imaging for resources on validating antibodies for IBEX.

Go To Top Version: 7    Revision Date: 01/24/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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