Alexa Fluor® 488 anti-mouse CD11a Antibody

Pricing & Availability
Clone
2D7 (See other available formats)
Regulatory Status
RUO
Other Names
αL integrin, LFA-1 α subunit, Ly-15, Ly-21, ITGAL
Isotype
Rat IgG2a, κ
2D7_A488_CD11a_Antibody_022222
C57 splenocytes were stained with anti-mouse CD11a (clone 2D7) Alexa Fluor® 488 (filled histogram) or rat IgG2a, κ Alexa Fluor® 488 isotype control (open histogram).
  • 2D7_A488_CD11a_Antibody_022222
    C57 splenocytes were stained with anti-mouse CD11a (clone 2D7) Alexa Fluor® 488 (filled histogram) or rat IgG2a, κ Alexa Fluor® 488 isotype control (open histogram).
Compare all formats See Alexa Fluor® 488 spectral data
Cat # Size Price Quantity Check Availability
162903 25 µg $101.00
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162904 100 µg $223.00
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Description

CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.


Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.

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Excitation Laser
Blue Laser (488 nm)
Additional Product Notes

* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.

RRID
AB_2922497 (BioLegend Cat. No. 162903)
AB_2922497 (BioLegend Cat. No. 162904)

Antigen Details

Structure
Integrin, associated with integrin CD18, 180 kD
Distribution

Lymphocytes, granulocytes, monocytes, macrophages

Function
Cellular adhesion
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50)
Cell Type
Granulocytes, Lymphocytes, Macrophages, Monocytes
Biology Area
Cell Biology, Immunology
Molecular Family
CD Molecules
Antigen References

1. .Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lub M, et al. 1995. Immunol. Today 16:479.

Gene ID
16408 View all products for this Gene ID
UniProt
View information about CD11a on UniProt.org
Go To Top Version: 1    Revision Date: 02/22/2022

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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