- Clone
- 2D7 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- αL integrin, LFA-1 α subunit, Ly-15, Ly-21, ITGAL
- Isotype
- Rat IgG2a, κ
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C57BL/6 splenocytes were stained with anti-mouse CD11a (clone 2D7) APC/Fire™ 750 (filled histogram) or rat IgG2a, κ APC/Fire™ 750 isotype control (open histogram).
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 162905 | 25 µg | $159.00 | |||
| 162906 | 100 µg | $382.00 | |||
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.06 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
* APC/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 774 nm. - Excitation Laser
-
Red Laser (633 nm)
- RRID
-
AB_3097443 (BioLegend Cat. No. 162905)
AB_3097443 (BioLegend Cat. No. 162906)
Antigen Details
- Structure
- Integrin, associated with integrin CD18, 180 kD
- Distribution
-
Lymphocytes, granulocytes, monocytes, macrophages
- Function
- Cellular adhesion
- Ligand/Receptor
- ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50)
- Cell Type
- Granulocytes, Lymphocytes, Macrophages, Monocytes
- Biology Area
- Cell Biology, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. .Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lub M, et al. 1995. Immunol. Today 16:479. - Gene ID
- 16408 View all products for this Gene ID
- UniProt
- View information about CD11a on UniProt.org
Other Formats
View All CD11a Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-mouse CD11a Antibody | 2D7 | FC,IHC-F |
| Alexa Fluor® 488 anti-mouse CD11a | 2D7 | FC |
| APC/Fire™ 750 anti-mouse CD11a | 2D7 | FC |
| PerCP/Cyanine5.5 anti-mouse CD11a | 2D7 | FC |
| Brilliant Violet 421™ anti-mouse CD11a | 2D7 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CD11a Antibody
C57BL/6 mouse splenocytes were stained with purified CD11a (... 
C57BL/6 mouse frozen spleen section was fixed with 4% parafo... -
Alexa Fluor® 488 anti-mouse CD11a
C57 splenocytes were stained with anti-mouse CD11a (clone 2D... -
APC/Fire™ 750 anti-mouse CD11a
C57BL/6 splenocytes were stained with anti-mouse CD11a (clon... -
PerCP/Cyanine5.5 anti-mouse CD11a
C57BL/6 splenocytes were stained with anti-mouse CD11a (clon... -
Brilliant Violet 421™ anti-mouse CD11a
C57BL/6 splenocytes were stained with anti-mouse CD11a (clon...