PE/Cyanine7 anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
30-F11_PECy7_090507
C57BL/6 mouse splenocytes stained with 30-F11 PE/Cyanine7
  • 30-F11_PECy7_090507
    C57BL/6 mouse splenocytes stained with 30-F11 PE/Cyanine7
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability
103113 25 µg $87.00
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103114 100 µg $190.00
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References

(PubMed link indicates BioLegend citation)
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Tran NT, et al. 2019. Cell Rep. 28:3510. PubMed
  2. Garber C, et al. 2019. Nat Neurosci. 1.802777778. PubMed
  3. Dobie R, et al. 2020. Cell Reports. 29(7):1832-1847.e8.. PubMed
  4. Wu JH, et al. 2020. EMBO Mol Med. 12:e10154. PubMed
  5. Khare A, et al. 2016. Cell Rep. 15: 1700-1714. PubMed
  6. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  7. Rodriguez de la Fuente L, et al. 2021. STAR Protoc. 2:100841. PubMed
  8. Yokozeki Y, et al. 2021. Biomed Res Int. 2021:7988320. PubMed
  9. Schädlich IS, et al. 2022. iScience. 25:104470. PubMed
  10. Yang AC, et al. 2020. Nature. 583:425. PubMed
  11. Chen G, et al. 2021. J Mol Cell Cardiol. 159:62. PubMed
  12. Kfoury YS, et al. 2021. Cell Stem Cell. 28:2090. PubMed
  13. He D, et al. 2022. Immunity. 55:159. PubMed
  14. Tapanes S, et al. 2022. Glia. 70:1133. PubMed
  15. Kenney DJ, et al. 2022. Cell Rep. 39:110714. PubMed
  16. Jeong GU, et al. 2022. Microbiol Spectr. 10:e0109122. PubMed
  17. Kiani Shabestari S, et al. 2022. Cell Rep. 39:110961. PubMed
  18. Dong H, et al. 2022. Proc Natl Acad Sci U S A. 119:e2123247119. PubMed
  19. Steudler J, et al. 2022. Glia. 70:2045. PubMed
  20. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  21. Koizumi M, et al. 2022. J Biol Chem. 298:102506. PubMed
  22. Xuan FL, et al. 2022. Front Immunol. 13:1005067. PubMed
  23. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  24. Moiseeva V, et al. 2023. Nature. 613:169. PubMed
  25. An X, et al. 2023. Am J Reprod Immunol. 89:e13676. PubMed
  26. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
  27. Taniguchi S, et al. 2023. Nat Commun. 14:143. PubMed
  28. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  29. Hattori Y, et al. 2023. Cell Rep. 42:112092. PubMed
  30. Ismailova A, et al. 2023. Front Immunol. 14:1123344. PubMed
  31. Zhao M, et al. 2023. J Nanobiotechnology. 21:50. PubMed
  32. Wei J, et al. 2022. Cancer Prev Res (Phila). 15:285. PubMed
  33. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  34. Narvaez del Pilar O, et al. 2022. Development. 149:. PubMed
  35. Gomez-Salinero JM, et al. 2022. Cell Stem Cell. 29:593. PubMed
  36. Hernandez BJ, et al. 2022. Am J Respir Cell Mol Biol. 67:389. PubMed
  37. Meyer T, et al. 2022. Proc Natl Acad Sci U S A. 119:e2211310119. PubMed
  38. Hong X, et al. 2022. Cell Stem Cell. 29:1298. PubMed
  39. Cronin SJF, et al. 2022. Sci Transl Med. 14:eabj1531. PubMed
  40. Mohamed GA, et al. 2023. Breast Cancer Res. 25:23. PubMed
  41. Zhu S, et al. 2023. J Nanobiotechnology. 21:81. PubMed
  42. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  43. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  44. Ma X, et al. 2023. Nat Commun. 14:1606. PubMed
  45. Tan X, et al. 2023. Adv Sci (Weinh). 10:e2206768. PubMed
  46. Sun JY, et al. 2023. Sci Adv. 9:eade4110. PubMed
  47. Zhang J, et al. 2023. Theranostics. 13:2226. PubMed
  48. Bobadilla Muñoz M, et al. 2023. Front Cell Dev Biol. 11:1128534. PubMed
  49. Hsieh MS, et al. 2023. NPJ Vaccines. 8:82. PubMed
  50. Zhang AQ, et al. 2023. Nat Biomed Eng. . PubMed
  51. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  52. Kim SS, et al. 2022. Cancers (Basel). 14:. PubMed
  53. García-Prat L, et al. 2020. Nat Cell Biol. 22:1307. PubMed
  54. Tatsuguchi T, et al. 2022. Int Immunol. 34:277. PubMed
  55. Pan J, et al. 2021. Mol Ther Nucleic Acids. 26:970. PubMed
  56. Helms EJ, et al. 2021. Cancer Discov. Online ahead of print. PubMed
  57. Huck NA, et al. 2021. J Neurosci. 41:4349. PubMed
  58. Wu Q, et al. 2021. Cancer Commun (Lond). Online ahead of prin. PubMed
  59. Ma Q, et al. 2021. Clin Transl Immunology. 10:e1300. PubMed
  60. Yagishita Y, et al. 2020. Cell Mol Gastroenterol Hepatol. . PubMed
  61. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
  62. Wagner G, et al. 2017. Sci Rep. 7:40881. PubMed
  63. Weeden C, et al. 2017. PLoS Biol. 10.1371/journal.pbio.2000731. PubMed
  64. Hilliard K, et al. 2015. Infect Immun . 83: 4015 - 4027. PubMed
  65. Shi Y, et al. 2020. Med Sci Monit. 26:e923328. PubMed
  66. Smith NR, et al. 2017. Cell Mol Gastroenterol Hepatol. 0.395138889. PubMed
  67. Zhou J, et al. 2019. Immunity. 50:403. PubMed
  68. Abels ER et al. 2019. Cell Rep. 28(12):3105-3119 . PubMed
  69. Chang T, et al. 2017. PLoS Pathog. 10.1371/journal.ppat.1006485. PubMed
  70. Wilson RP, et al. 2019. PLoS Pathog. 15:e1007745. PubMed
  71. Barry KC, et al. 2018. Nat Med. 24:1178. PubMed
  72. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
  73. Mansouri N, et al. 2019. JCI Insight. 4:e128060. PubMed
  74. Vila Ellis L, et al. 2020. Dev Cell. 617:52. PubMed
  75. Kim YS, et al. 2021. Cell Death Dis. 12:307. PubMed
  76. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  77. Manivasagam S, et al. 2022. J Immunol. 208:1341. PubMed
  78. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  79. Greenberg J, et al. 2022. JCI Insight. Online ahead of print. PubMed
  80. White MPJ, et al. 2020. Front Immunol. 11:1830. PubMed
  81. Saito S, et al. 2020. Nutrients. 12:. PubMed
  82. Fu Y, et al. 2020. Mol Ther. 1214:28. PubMed
  83. Han Y, et al. 2020. Nat Commun. 11:1776. PubMed
  84. Wang B, et al. 2017. EBioMedicine. 10.1016/j.ebiom.2017.03.041. PubMed
  85. Kaczmarek–Hájek K, et al. 2018. Elife. 7:e36217. PubMed
  86. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  87. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  88. Zhong J, et al. 2018. Sci Adv. 4:eaas9864. PubMed
  89. Kobayashi H, et al. 2020. STAR Protoc. 1:100078. PubMed
  90. Mathews J, et al. 2014. PLoS One. 9:97707. PubMed
  91. Britschgi A, et al. 2017. Nature. 541:541-545. PubMed
  92. Valds-Mora F, et al. 2021. Cell Reports. 35(2):108945. PubMed
  93. DellOrso S, et al. 2021. STAR Protocols. 2(2):100451. PubMed
  94. Little DR, et al. 2021. Nat Commun. 12:2509. PubMed
  95. Bhopale VM, et al. 2021. J Appl Physiol (1985). 130:1604. PubMed
  96. Zheng L, et al. 2022. J Neuroinflammation. 19:128. PubMed
  97. Campanario S, et al. 2021. Front Cell Dev Biol. 8:620409. PubMed
  98. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  99. Jiang YH, et al. 2020. J Mol Cell Cardiol. 138:115. PubMed
  100. Pan J, et al. 2020. J Neuroinflammation. 17:97. PubMed
  101. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  102. Garber C, et al. 2018. Nat Immunol. 19:151. PubMed
  103. Wang B,et al. 2017. Cell Discov.. 10.1038/celldisc.2017.36. PubMed
  104. Solanas G, et al. 2017. Cell. 170:678. PubMed
  105. Dubey LK, et al. 2019. Cell Rep. 27:2442. PubMed
  106. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  107. Galvão I, et al. 2018. Front Immunol. 9:142. PubMed
  108. Mizuochi C, et al. 2012. PLoS One. 7:e35763. PubMed
  109. Gigliotti J, et al. 2013. J Am Soc Nephrol. 24:1451. PubMed
  110. Yang R, et al. 2022. Front Pharmacol. 13:774440. PubMed
  111. Fix DK, et al. 2021. Aging Cell. 20:e13448. PubMed
  112. Cassidy BR, et al. 2020. J Neuroinflammation. 17:259. PubMed
  113. Zhu L, et al. 2021. Stem Cell Res Ther. 12:408. PubMed
  114. Bahar Halpern K, et al. 2020. Nat Commun. 11:1936. PubMed
  115. Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
  116. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  117. McGowan SE, et al. 2018. Am J Physiol Lung Cell Mol Physiol. 315:L102. PubMed
  118. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  119. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  120. Onder L et al. 2017. Immunity. 47(1):80-92 . PubMed
  121. Halpern KB, et al. 2018. Nat Biotechnol. 36:962. PubMed
  122. Kimbrough D, et al. 2018. J Mol Cell Cardiol. 119:51. PubMed
  123. Codina A, et al. 2019. Cell Syst. 8:136. PubMed
  124. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  125. Wang W, et al. 2020. Immunity. 51(6):1102-1118.e7.. PubMed
  126. Allen S, et al. 2011. J Virol. 85:11448. PubMed
  127. Jaworska K, et al. 2015. J Immunol. 194:325. PubMed
  128. Furuya Y, et al. 2015. PLoS Pathog. 11: 1005180. PubMed
  129. Gomzikova MO, et al. 2020. Sci Rep. 10:10740. PubMed
  130. Cain MP, et al. 2020. Dis Model Mech. 13:00. PubMed
  131. Court AC, et al. 2020. EMBO Rep. 21:e48052. PubMed
  132. Okubo K, et al. 2021. Cell Reports. 35(7):109142. PubMed
  133. Huang CH, et al. 2020. Adv Ther (Weinh). 3:. PubMed
  134. Mao FY, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:395. PubMed
  135. Okamura T, et al. 2021. Front Immunol. 12:669629. PubMed
  136. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  137. Basu A, et al. 2021. Cancer Immunol Res. Online ahead of print. PubMed
  138. Fennell LM, et al. 2020. EMBO J. 39:e103303. PubMed
  139. Ellegast JM, et al. 2022. Cancer Discov. 12:1760. PubMed
  140. Liu T, et al. 2022. Front Immunol. 13:901349. PubMed
  141. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  142. Manco R, et al. 2021. Nat Commun. 12:3074. PubMed
  143. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  144. Berg AL, et al. 2022. Cancers (Basel). 14:. PubMed
  145. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  146. McCoy S 2015. Am J Physiol Lung Cell Mol Physiol. 309: L463-L474. PubMed
  147. Yen Y, et al. 2008. J Virol. 82:12312. PubMed
  148. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  149. Son NH, et al. 2018. J Clin Invest. 128:4329. PubMed
  150. Kellish P, et al. 2019. J Clin Invest. 130:2279. PubMed
  151. Magri G et al. 2017. Immunity. 47(1):118-134 . PubMed
  152. Ishii H, et al. 2012. Cell Death Dis. 9;3:e363. PubMed
  153. Wang F, et al. 2021. Cell. 184(2):422-440.e17. PubMed
  154. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  155. Sela Y, et al. 2021. Elife. 10: . PubMed
  156. Pascual G, et al. 2021. Nature. 599:485. PubMed
  157. Kolodziejczyk AA, et al. 2020. Nat Med. 26:1899. PubMed
  158. Galle-Treger L, et al. 2020. J Allergy Clin Immunol. 145:502. PubMed
  159. Chu X, et al. 2021. Front Cell Dev Biol. 9:671841. PubMed
  160. Shafiei-Jahani P, et al. 2021. Nat Commun. 12:2526. PubMed
  161. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  162. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  163. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  164. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
  165. Kobayashi H, et al. 2020. Cell Reports. 28(1):145-158.e9.. PubMed
  166. Wu X, et al. 2016. Sci Rep. 6:18685. PubMed
  167. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  168. Evgin L, et al. 2020. Nat Commun. 2.671527778. PubMed
  169. van Gastel N, et al. 2020. Cell Metabolism. 32(3):391-403.e6. PubMed
  170. Merrell AJ, et al. 2021. Hepatology. 74:444. PubMed
  171. Jin L, et al. 2022. J Immunol Res. 2022:7222638. PubMed
  172. Koyama T, et al. 2022. Curr Issues Mol Biol. 44:3146. PubMed
  173. Evgin L, et al. 2022. Sci Transl Med. 14:eabn2231. PubMed
  174. Shen DD, et al. 2022. Mol Cancer. 21:75. PubMed
  175. Zhu J, et al. 2021. Cancer Cell Int. 21:529. PubMed
  176. Yuan M, et al. 2022. Oxid Med Cell Longev. 2022:5479491. PubMed
  177. Abdelfattah N, et al. 2022. Nat Commun. 13:767. PubMed
  178. Li J, et al. 2020. Development. :. PubMed
  179. Tang Z, et al. 2021. Stem Cell Res Ther. 12:397. PubMed
  180. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  181. Nenasheva T, et al. 2017. PLoS One. 12(6):e0178983. PubMed
  182. Li S, et al. 2019. Front Neurol. 1.036805556. PubMed
  183. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  184. Magness S, et al. 2013. Am J Physiol Gastrointest Liver Physiol. 305:542. PubMed
  185. Wang W, et al. 2021. STAR Protocols. 2(3):100756. PubMed
  186. Mohammadpour H, et al. 2021. Cell Rep. 37:109883. PubMed
  187. Zhu S, et al. 2022. EBioMedicine. 80:104060. PubMed
  188. Sung PS, et al. 2022. JCI Insight. :. PubMed
  189. Zhang J, et al. 2022. Biomater Res. 26:44. PubMed
  190. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  191. Nian Z, et al. 2021. Clin Cancer Res. 27:6026. PubMed
  192. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  193. Hakim R, et al. 2021. J Neurosci. 41:8441. PubMed
  194. Ognjenovic NB, et al. 2020. Dev Cell. 55:544. PubMed
  195. Gu H, et al. 2021. Elife. 10:. PubMed
  196. Hendee K, et al. 2021. Aging (Albany NY). 13:7781. PubMed
  197. Issah Y, et al. 2021. Elife. 10:. PubMed
  198. Namkoong H, et al. 2018. PLoS Pathog. 14:e1006955. PubMed
  199. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  200. Smith NR, et al. 2018. Cell Mol Gastroenterol Hepatol. 6:79. PubMed
  201. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  202. Hering L, et al. 2020. Front Immunol. 1.747222222. PubMed
  203. Di Pilato M, et al. 2021. Cell. 184(17):4512-4530.e22. PubMed
  204. Béchade C, et al. 2020. Glia. . PubMed
  205. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  206. Rai S, et al. 2022. Nat Commun. 13:5346. PubMed
  207. Fan X, et al. 2020. Acta Physiol (Oxf). 230:e13475. PubMed
  208. Fang Y, et al. 2022. Development. 149:. PubMed
  209. Boyce M, et al. 2022. Cells. 11:. PubMed
  210. Gong P, et al. 2022. Cell Death Discov. 8:466. PubMed
  211. Oh J, et al. 2021. Clin Cancer Res. 27:4781. PubMed
  212. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  213. Li Q, et al. 2022. J Biol Chem. :101753. PubMed
  214. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  215. Andreou T, et al. 2021. J Immunother Cancer. 9:. PubMed
  216. Rochford I, et al. 2021. Am J Physiol Lung Cell Mol Physiol. 321:L686. PubMed
  217. Sheng J, et al. 2021. eLife. 10:00. PubMed
  218. Moreno M et al. 2014. The Journal of Neuroscience. 34(24):8175-85 . PubMed
  219. Nguyen HX et al. 2017. J Neurosci. 37(38):9269-9287 . PubMed
  220. Ishihara J, et al. 2018. Nat Commun. 9:2163. PubMed
  221. Ghosh S, et al. 2019. Commun Biol. 0.325. PubMed
  222. Hussein M, et al. 2015. PLoS One. 10: 0135218. PubMed
  223. Gigliotti J, et al. 2015. J Am Soc Nephrol. 26: 2470 - 2481. PubMed
  224. Serr I, et al. 2016. Nat Commun. 7:10991. PubMed
  225. Gerner-Mauro KN, et al. 2020. Proc Natl Acad Sci U S A. 117:12182. PubMed
  226. Kimmel JC, et al. 2021. Cell Reports. 35(4):109046. PubMed
  227. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  228. Dourcy M, et al. 2020. Mucosal Immunol. 13:799. PubMed
  229. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  230. Chithanathan K, et al. 2022. Biology (Basel). 11:. PubMed
  231. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  232. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  233. Song X, et al. 2021. FEBS Open Bio. 11:2453. PubMed
  234. Ren X, et al. 2021. Cell Death Dis. 12:484. PubMed
  235. Wu H, et al. 2020. Cell. 180(1):107-121.e17.. PubMed
  236. Muri J, et al. 2020. Cell Reports. 30(13):4399-4417. PubMed
RRID
AB_312978 (BioLegend Cat. No. 103113)
AB_312978 (BioLegend Cat. No. 103114)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05/14/2013

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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