Purified anti-human CD137 (4-1BB) Antibody

Pricing & Availability
Clone
S18014C (See other available formats)
Regulatory Status
RUO
Other Names
4-1BB, ILA, CDw137, TNFRSF9
Isotype
Mouse IgG1, κ
S18014C_PURE_CD137_Antibody_101620
PHA-stimulated (3 days) human peripheral blood mononuclear cells stained with purified anti-human CD137 (4-1BB) (clone S18014C) (left) or purified mouse IgG1, κ isotype control (right), followed by goat anti-mouse IgG PE. Cells were co-stained with APC anti- CD3.
  • S18014C_PURE_CD137_Antibody_101620
    PHA-stimulated (3 days) human peripheral blood mononuclear cells stained with purified anti-human CD137 (4-1BB) (clone S18014C) (left) or purified mouse IgG1, κ isotype control (right), followed by goat anti-mouse IgG PE. Cells were co-stained with APC anti- CD3.
Compare all formats
Cat # Size Price Quantity Check Availability
300802 100 µg $129.00
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD137 is a 39 kD transmembrane protein also known as 4-1BB. It is expressed on activated T cells. CD137 is a type I membrane protein and a member of the tumor necrosis factor receptor superfamily. CD137 appears to be important for T cell proliferation and survival, and induces monocyte activation through its interaction with 4-1BB ligand.

Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human CD137-Fc
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2888854 (BioLegend Cat. No. 300802)

Antigen Details

Structure
TNFR superfamily, type I transmembrane protein, 30 kD
Distribution

Activated T cells

Function
T cell costimulation
Ligand/Receptor
4-1BB ligand (CD137L)
Cell Type
Lymphocytes, NK cells, NKT cells, T cells
Biology Area
Costimulatory Molecules, Immuno-Oncology, Immunology, Signal Transduction
Molecular Family
CD Molecules
Antigen References
  1. Gruss HJ & Dower SK. 1995. Blood. 85:3378-404.
  2. Sica G & Chen L. 2000. Adv Exp Med Biol. 465:355-62.
  3. Alderson MR, et al. 1994. Eur J Immunol. 24:2219-27.
  4. Schwarz H, et al. 1996. Blood 87:2839-45.
Gene ID
3604 View all products for this Gene ID
UniProt
View information about CD137 on UniProt.org
Go To Top Version: 1    Revision Date: 10/05/2020

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Login/Register
Forgot your password? Reset Password
Request an Account