- Clone
- HI10a (See other available formats)
- Regulatory Status
- RUO
- Workshop
- V CD10.7
- Other Names
- Common acute lymphoblastic leukemia antigen (CALLA), Enkephalinase, Neutral endopeptidase, Neprilysin
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
312237 | 25 tests | $209 | ||||
312238 | 100 tests | $396 |
CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.
Product DetailsProduct Details
- Verified Reactivity
- Human, Cynomolgus, Rhesus
- Reported Reactivity
- African Green, Baboon, Capuchin monkey, Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 785™ under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 785™ excites at 405 nm and emits at 785 nm. The bandpass filter 780/60 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 785™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
-
Violet Laser (405 nm)
- RRID
-
AB_2860830 (BioLegend Cat. No. 312237)
AB_2860830 (BioLegend Cat. No. 312238)
Antigen Details
- Structure
- Type II transmembrane metalloprotease family, 100 kD
- Distribution
-
B cell precursors, T cell precursors, neutrophils
- Function
- Zinc-binding metalloproteinase, B cell development
- Ligand/Receptor
- Biologically active peptides including opioid enkephalins, bradykinin, angiotensions I & II
- Cell Type
- B cells, Neutrophils
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Shipp M, et al. 1993. Blood 82:1052.
2. Lu B, et al. 1995. J. Exp. Med. 181:2271. - Gene ID
- 4311 View all products for this Gene ID
- UniProt
- View information about CD10 on UniProt.org
Related FAQs
Other Formats
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD10
Nalm-6 cell line stained with purified HI10a and detected wi... -
PE anti-human CD10
Human peripheral blood granulocytes were stained with CD10 (... -
PE/Cyanine5 anti-human CD10
Human pre- B cell line REH stained with HI10a PE/Cyanine5 -
FITC anti-human CD10
Human pre-B cell line REH stained with HI10a FITC -
APC anti-human CD10
Nalm-6 cell line stained with purified HI10a and detected wi... -
APC/Cyanine7 anti-human CD10
Human peripheral blood granulocytes were stained with CD10 (... -
PE/Cyanine7 anti-human CD10
Human peripheral blood granulocytes stained with HI10a PE/Cy... -
PerCP/Cyanine5.5 anti-human CD10
Human peripheral blood granulocytes were stained with CD10 (... -
Brilliant Violet 421™ anti-human CD10
Human pre-B cell line REH was stained with CD10 (clone HI10a... -
Brilliant Violet 510™ anti-human CD10
Human peripheral blood granulocytes were stained with CD10 (... -
Brilliant Violet 605™ anti-human CD10
Human peripheral blood granulocytes were stained with anti-h... -
Purified anti-human CD10 (Maxpar® Ready)
Human PBMCs (top) and human NALM-6 pre-B cells (bottom) stai... -
Brilliant Violet 711™ anti-human CD10
Human peripheral blood granulocytes were stained with CD10 (... -
PE/Dazzle™ 594 anti-human CD10
Human peripheral blood granulocytes were stained with CD10 (... -
APC/Fire™ 750 anti-human CD10
Human peripheral blood granulocytes were stained with anti-h... -
APC anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
PE anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
FITC anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
TotalSeq™-A0062 anti-human CD10
-
TotalSeq™-C0062 anti-human CD10
-
APC/Fire™ 750 anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
TotalSeq™-B0062 anti-human CD10
-
PE/Cyanine7 anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
PerCP/Cyanine5.5 anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
Brilliant Violet 785™ anti-human CD10
Human peripheral blood granulocytes was stained with anti-hu... -
TotalSeq™-D0062 anti-human CD10
-
GMP APC anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
GMP FITC anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
GMP PE/Cyanine7 anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
GMP PE anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
PE/Dazzle™ 594 anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
GMP PerCP/Cyanine5.5 anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
Brilliant Violet 650™ anti-human CD10
Human peripheral blood granulocytes were stained with anti-h... Human peripheral blood lymphocytes, monocytes, and granulocy... -
GMP PE/Dazzle™ 594 anti-human CD10
Typical results from human peripheral blood granulocytes sta... -
Brilliant Violet 750™ anti-human CD10
Human peripheral blood granulocytes were stained anti-human ... Human peripheral blood cells were stained with anti-human CD... -
Spark Violet™ 423 anti-human CD10
Human peripheral blood granulocytes were stained with anti-h... -
Spark YG™ 593 anti-human CD10
Human peripheral blood granulocytes were stained with anti-h... Human peripheral blood granulocytes were stained with anti-h... -
Spark Blue™ 574 anti-human CD10
Human peripheral blood granulocytes were stained with anti-h... -
PE/Fire™ 640 anti-human CD10
Human peripheral blood granulocytes were stained with anti-h...
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