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Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
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Product Citations
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93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
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101301 50 µg 36 CHF
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101302 500 µg 115 CHF
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Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References

(PubMed link indicates BioLegend citation)
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  2. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  3. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  4. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  5. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  6. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  7. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  8. Barkaway A, et al. 2021. Immunity. . PubMed
  9. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  10. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  11. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  12. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  13. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  14. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  15. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  16. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  17. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  18. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  19. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  20. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  21. Jebbawi F, et al. 2021. Parasite Immunol. 43:e12834. PubMed
  22. Thomas R, et al. 2021. Immunology. 163:478. PubMed
  23. Herz J, et al. 2021. Neuron. 109:3609. PubMed
  24. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  25. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  26. Kozuki S, et al. 2022. Genes Cells. 27:192. PubMed
  27. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  28. Guttman O, et al. 2022. J Cell Biol. 221: . PubMed
  29. Miyao T, et al. 2022. Elife. 11: . PubMed
  30. Yin K, et al. 2022. Genes Dev. 36:533. PubMed
  31. Malhi H, et al. 2022. Cell Rep Med. 3:100658. PubMed
  32. Zhang Y, et al. 2022. Vaccines (Basel). 10: . PubMed
  33. Sugimoto S, et al. 2022. Nat Metab. 4:775. PubMed
  34. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  35. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  36. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  37. Akalu YT, et al. 2022. Elife. 11: . PubMed
  38. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  39. Bottermann K, et al. 2022. Basic Res Cardiol. 117:48. PubMed
  40. Hao J, et al. 2022. Cell Rep. 41:111804. PubMed
  41. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  42. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  43. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  44. Ullah I, et al. 2023. Cell Rep Med. 4:100893. PubMed
  45. Al-Saafeen BH, et al. 2023. Front Immunol. 13:1017780. PubMed
  46. Cousin N, et al. 2022. Cells. 12: . PubMed
  47. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  48. Tichet M, et al. 2023. Immunity. 56:162. PubMed
  49. Zhou H, et al. 2023. Front Immunol. 13:1059687. PubMed
  50. Mandour MF, et al. 2023. Front Med (Lausanne). 9:1057252. PubMed
  51. Kemna J, et al. 2023. Nat Immunol. 24:414. PubMed
  52. Novaj A, et al. 2023. Int J Mol Sci. 24: . PubMed
  53. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  54. Liu X, et al. 2022. Pain. 163:508. PubMed
  55. Zhang M, et al. 2022. Mol Imaging Biol. 24:280. PubMed
  56. Zhang W, et al. 2022. Dev Cell. 57:329. PubMed
  57. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  58. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  59. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  60. Zhang H, et al. 2022. Nat Cancer. 3:808. PubMed
  61. Fang Y, et al. 2022. Sci Immunol. 7:eabp9962. PubMed
  62. Koch MS, et al. 2022. Mol Ther Oncolytics. 26:275. PubMed
  63. Harapas CR, et al. 2022. Sci Immunol. 7:eabi4611. PubMed
  64. Ding P, et al. 2022. Elife. 11:. PubMed
  65. Deák P, et al. 2022. Cell Rep. 41:111563. PubMed
  66. Zhong J, et al. 2022. J Adv Res. 41:145. PubMed
  67. Melo-Silva CR, et al. 2022. Cell Rep. 41:111676. PubMed
  68. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  69. Wu Q, et al. 2023. Front Immunol. 13:1081719. PubMed
  70. Li L, et al. 2023. iScience. 26:106095. PubMed
  71. Torrente D, et al. 2023. J Neuroinflammation. 20:56. PubMed
  72. Bai X, et al. 2023. Nat Commun. 14:1247. PubMed
  73. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  74. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  75. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  76. Kudo T, et al. 2023. iScience. 26:106342. PubMed
  77. Liu KY, et al. 2023. Environ Health Perspect. 131:37014. PubMed
  78. Zhang YN, et al. 2023. Nat Commun. 14:1985. PubMed
  79. Iguchi A, et al. 2023. iScience. 26:106375. PubMed
  80. Feng Y, et al. 2023. J Transl Med. 21:290. PubMed
  81. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  82. Liu JC, et al. 2023. Int J Mol Sci. 24:. PubMed
  83. Petenkova A, et al. 2023. Nat Commun. 14:2761. PubMed
  84. Xu J, et al. 2023. Discov Oncol. 14:68. PubMed
  85. An R, et al. 2022. Cell Insight. 1:100047. PubMed
  86. Wang K, et al. 2023. Nat Commun. 14:2950. PubMed
  87. Amirova KM, et al. 2023. Int J Mol Sci. 24:. PubMed
  88. Li M, et al. 2023. BMC Cancer. 23:497. PubMed
  89. Mawambo G, et al. 2023. J Neuroinflammation. 20:145. PubMed
  90. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  91. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  92. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  93. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  94. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  95. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  96. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  97. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  98. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  99. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  100. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  101. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  102. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  103. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  104. Mevel R, et al. 2020. eLife. 9:00. PubMed
  105. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  106. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  107. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  108. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  109. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  110. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  111. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  112. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  113. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  114. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  115. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  116. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  117. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  118. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  119. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  120. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  121. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  122. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  123. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  124. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  125. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  126. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  127. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  128. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  129. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  130. Feng J, et al. 2021. iScience. 24:103004. PubMed
  131. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  132. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  133. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  134. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  135. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  136. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  137. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  138. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  139. Goel S, et al. 2017. Nature. 548:471. PubMed
  140. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  141. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  142. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  143. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  144. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  145. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  146. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  147. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  148. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  149. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  150. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  151. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  152. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  153. Diao L, et al. 2022. iScience. 25:105511. PubMed
  154. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  155. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  156. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  157. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  158. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  159. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  160. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  161. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  162. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  163. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  164. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  165. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  166. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  167. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  168. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  169. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  170. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  171. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  172. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  173. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  174. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  175. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  176. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  177. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  178. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  179. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  180. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  181. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  182. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  183. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  184. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  185. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  186. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  187. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  188. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  189. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  190. Tal MC, et al. 2020. MBio. 11:00. PubMed
  191. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  192. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  193. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  194. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  195. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  196. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  197. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  198. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  199. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  200. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  201. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  202. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  203. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  204. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  205. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  206. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  207. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  208. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  209. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  210. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  211. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  212. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  213. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  214. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  215. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  216. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  217. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  218. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  219. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  220. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  221. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  222. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  223. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  224. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  225. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  226. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  227. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  228. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  229. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  230. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  231. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  232. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  233. Wong HS, et al. 2021. Cell. . PubMed
  234. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  235. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  236. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  237. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  238. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  239. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  240. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  241. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  242. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  243. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  244. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  245. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  246. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  247. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  248. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  249. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  250. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  251. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  252. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  253. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  254. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  255. Baasch S, et al. 2021. Cell. . PubMed
  256. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  257. Zheng J, et al. 2020. bioRxiv. . PubMed
  258. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  259. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  260. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  261. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  262. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  263. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  264. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  265. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  266. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  267. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  268. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  269. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  270. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  271. Xu S, et al. 2021. Immunity. . PubMed
  272. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  273. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  274. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  275. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  276. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  277. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  278. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  279. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  280. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  281. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  282. Welte T, et al. 2021. iScience. 24:103349. PubMed
  283. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  284. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  285. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  286. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  287. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  288. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  289. Roy K, et al. 2019. Immunity. 50:616. PubMed
  290. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  291. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  292. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  293. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  294. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  295. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  296. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  297. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  298. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  299. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  300. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  301. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  302. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  303. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  304. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  305. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  306. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  307. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  308. Zheng J, et al. 2020. Nature. . PubMed
  309. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  310. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  311. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  312. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  313. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  314. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  315. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  316. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  317. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  318. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  319. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  320. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  321. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  322. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  323. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  324. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  325. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  326. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  327. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  328. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  329. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  330. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  331. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  332. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  333. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  334. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  335. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  336. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  337. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  338. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  339. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  340. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  341. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  342. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  343. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  344. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  345. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  346. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  347. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  348. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  349. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  350. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  351. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  352. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  353. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  354. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  355. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  356. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  357. Lenert R 2005. J Immunol. 174:2429. PubMed
  358. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  359. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  360. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  361. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  362. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  363. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  364. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  365. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  366. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  367. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  368. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  369. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  370. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  371. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  372. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  373. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  374. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  375. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  376. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  377. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  378. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  379. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  380. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  381. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  382. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  383. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  384. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  385. Lee SA, et al. 2021. Cells. 10:. PubMed
  386. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  387. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  388. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  389. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  390. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  391. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  392. William M, et al. 2018. J Immunol. 200:4102. PubMed
  393. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  394. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  395. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  396. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  397. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  398. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  399. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  400. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  401. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  402. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  403. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  404. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  405. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  406. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  407. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  408. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  409. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  410. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  411. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  412. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  413. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  414. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  415. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  416. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  417. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  418. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  419. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  420. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  421. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  422. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  423. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  424. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  425. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  426. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  427. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  428. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  429. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  430. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  431. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  432. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  433. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  434. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  435. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  436. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  437. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  438. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  439. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  440. Sibler E, et al. 2021. Cells. 10:. PubMed
  441. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  442. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  443. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  444. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  445. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  446. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  447. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  448. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  449. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  450. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
  451. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  452. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  453. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  454. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  455. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  456. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  457. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312800 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
UniProt
View information about CD16/32 on UniProt.org
Go To Top Version: 2    Revision Date: 01.23.2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

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