- Clone
- SA231A2 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CLEC15A, MAFA-L, MAFA-2F1, MAFA-LIKE, 2F1
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![SA231A2_PEFire640_KLRG1_Antibody_update_031423 SA231A2_PEFire640_KLRG1_Antibody_update_031423](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/SA231A2_PEFire640_KLRG1_Antibody_update_031423.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes were stained with anti-human CD56 Brilliant Violet 421™ and anti-human KLRG1 (MAFA) (clone SA231A2) PE/Fire™ 640 (left) or stained with anti-human CD56 Brilliant Violet 421™ only (right).
Cat # | Size | Price | Save |
---|---|---|---|
367741 | 25 tests | ¥45,320 | |
367742 | 100 tests | ¥94,380 |
Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a 30 kD, type II membrane glycoprotein with one C-type lectin domain and one immunoreceptor tyrosine-based inhibititory motif (ITIM). KLRG1 is expressed by subsets of NK, effector and memory T cells. KLRG1 inhibits cell activation and proliferation, and is a marker of T cell senescence. Binding of KLRG1 to E-, N-, or R- cadherins blocks phosphorylation of Akt and increases the expression of cell cycle inhibitors.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human KLRG1-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Fire™ 640 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PE/Fire™ 640 has a maximum excitation of 566 nm and a maximum emission of 639 nm.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2936704 (BioLegend Cat. No. 367741)
AB_2936704 (BioLegend Cat. No. 367742)
Antigen Details
- Structure
- Type II membrane glycoprotein, one C-type lectin domain, one ITIM, 30 kD.
- Distribution
-
Subsets of NK, effector and memory T cells.
- Function
- Inhibits cell activation and proliferation, marker of T cell senescence.
- Interaction
- AKT
- Ligand/Receptor
- E-, N-, and R- cadherins
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Antigen References
-
1. Shi L, et al. 2014. J. Immunol. 192:649.
- Gene ID
- 10219 View all products for this Gene ID
- UniProt
- View information about KLRG1 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All KLRG1 Reagents Request Custom ConjugationCompare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 Br... -
Alexa Fluor® 647 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD16 Br... -
Brilliant Violet 421™ anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 PE... -
PerCP/Cyanine5.5 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
PE/Dazzle™ 594 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
APC anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 PE... -
PE anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
FITC anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
APC/Fire™ 750 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 PE... -
PE/Cyanine7 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 FI... -
TotalSeq™-A0153 anti-human KLRG1 (MAFA)
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APC/Cyanine7 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 FI... -
KIRAVIA Blue 520™ anti-human KLRG1 (MAFA) Antibody
Human peripheral blood lymphocytes were stained with CD56 PE... -
TotalSeq™-B0153 anti-human KLRG1 (MAFA) Antibody
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Alexa Fluor® 700 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 PE... -
APC/Fire™ 810 anti-human KLRG1 (MAFA) Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
TotalSeq™-D0153 anti-human KLRG1 (MAFA)
-
PE/Fire™ 810 anti-human KLRG1 (MAFA) Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
TotalSeq™-C0153 anti-human KLRG1 (MAFA)
-
Spark NIR™ 685 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Fire™ 640 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
Brilliant Violet 711™ anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
PerCP/Fire™ 780 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
PerCP/Fire™ 806 anti-human KLRG1 (MAFA)
Human lysed whole blood cells were stained with anti-human C... -
PE/Fire™ 700 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Fire™ 744 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu...
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