Loading...

PE/Cyanine7 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
M1slash70_PECy7_042706
C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram) (gated on total cells).
  • M1slash70_PECy7_042706
    C57BL/6 mouse bone marrow cells were stained with CD11b (clone M1/70) PE/Cyanine7 (filled histogram) or rat IgG2b, κ PE/Cyanine7 isotype control (open histogram) (gated on total cells).
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
101215 25 µg 70€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101216 100 µg 169€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Hatzi K, et al. 2019. Nat Immunol. 20:86. PubMed
  2. Tran NT, et al. 2019. Cell Rep. 28:3510. PubMed
  3. Lin C et al. 2019. Immunity. 50(1):137-151 . PubMed
  4. Okunuki Y, et al. 2018. Proc Natl Acad Sci U S A. 115:E6264. PubMed
  5. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  6. Wang L, et al. 2021. J Nanobiotechnology. 19:56. PubMed
  7. Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
  8. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  9. Cheresh P, et al. 2021. Int J Mol Sci. 22:. PubMed
  10. Deng R, et al. 2022. Adv Sci (Weinh). 9:e2103343. PubMed
  11. Odom CV, et al. 2021. J Immunol. 207:1891. PubMed
  12. Denny L, et al. 2021. Clin Transl Immunology. 10:e1234. PubMed
  13. Janbandhu V, et al. 2022. Cell Stem Cell. 29:281. PubMed
  14. Cohen K, et al. 2021. Cell Rep. 37:110026. PubMed
  15. Aimaitijiang A, et al. 2022. Genes Cells. 27:25. PubMed
  16. Schnell A, et al. 2021. Cell. 184:6281. PubMed
  17. Zhou Y, et al. 2022. Br J Pharmacol. 179:1978. PubMed
  18. Hiyoshi H, et al. 2022. Cell Host Microbe. 30:163. PubMed
  19. Wang B, et al. 2022. EMBO J. 41:e108946. PubMed
  20. Wang S, et al. 2022. Sci Adv. 8:eabn3883. PubMed
  21. Du Y, et al. 2022. J Exp Med. 219: . PubMed
  22. Pannunzio B, et al. 2022. Cells. 11: . PubMed
  23. Marié IJ, et al. 2022. Bio Protoc. 12:e4438. PubMed
  24. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  25. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  26. Liu Z, et al. 2022. Cancer Commun (Lond). 42:971. PubMed
  27. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  28. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  29. Lu Z, et al. 2022. Cell Rep. 41:111482. PubMed
  30. Mansouri S, et al. 2022. J Immunol. 209:2114. PubMed
  31. Yoo HJ, et al. 2022. Cell Rep. 41:111598. PubMed
  32. Papaxenopoulou LA, et al. 2022. iScience. 25:105522. PubMed
  33. Zhang Y, et al. 2022. Front Oncol. 12:1042250. PubMed
  34. He Y, et al. 2022. Front Immunol. 13:986202. PubMed
  35. Lee DE, et al. 2022. Nat Commun. 13:7613. PubMed
  36. Kraemer AN, et al. 2022. Front Immunol. 13:933191. PubMed
  37. Choi H, et al. 2023. J Nanobiotechnology. 21:5. PubMed
  38. Wang D, et al. 2023. J Exp Clin Cancer Res. 42:26. PubMed
  39. Leinenga G, et al. 2023. Bioeng Transl Med. 8:e10329. PubMed
  40. Wang R, et al. 2023. iScience. 26:105954. PubMed
  41. Slusarczyk P, et al. 2023. Elife. 12: . PubMed
  42. Ernst MPT, et al. 2023. Hemasphere. 7:e824. PubMed
  43. Drijvers JM, et al. 2021. Cancer Immunol Res. 9:184. PubMed
  44. Yeh CH, et al. 2022. Immunity. 55:272. PubMed
  45. Parsons M, et al. 2014. J Immunol. 192:1361. PubMed
  46. Tebartz C, et al. 2015. J Immunol. 194:1100. PubMed
  47. Quispe Calla N, et al. 2016. Sci Rep. 6:37723. PubMed
  48. D'Alessandro G, et al. 2020. Eur J Immunol. 50:705. PubMed
  49. DeSouza-Vieira T, et al. 2020. Cell Rep. 33:108317. PubMed
  50. Gogoi H, et al. 2020. Front Immunol. 1.620833333. PubMed
  51. Liu K, et al. 2021. Cell Metabolism. 33(3):666-675.e4. PubMed
  52. Sheng YH, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:789. PubMed
  53. Banerjee K, et al. 2023. Eur J Immunol. 53:e2250161. PubMed
  54. Mela V, et al. 2023. Mol Neurobiol. 60:3044. PubMed
  55. Schönberger K, et al. 2023. Anal Chem. 95:4325. PubMed
  56. Li L, et al. 2023. iScience. 26:106095. PubMed
  57. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  58. Gupta T, et al. 2023. Front Immunol. 14:1044703. PubMed
  59. MacPherson KP, et al. 2023. Front Cell Neurosci. 17:895017. PubMed
  60. Martins Nascentes Melo L, et al. 2023. J Immunother Cancer. 11:. PubMed
  61. Pastrez PRA, et al. 2023. Cancers (Basel). 15:. PubMed
  62. Yao H, et al. 2023. Front Immunol. 14:1147674. PubMed
  63. Hernandez VG, et al. 2023. Glia. 71:1960. PubMed
  64. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  65. Lu Y, et al. 2023. J Transl Med. 21:339. PubMed
  66. Bobadilla Muñoz M, et al. 2023. Front Cell Dev Biol. 11:1128534. PubMed
  67. Doloff JC, et al. 2023. Sci Adv. 9:eade9488. PubMed
  68. Ye S, et al. 2023. Front Oncol. 13:1202750. PubMed
  69. Giorgetti E, et al. 2020. Cell Reports. 29(6):1539-1554.e7.. PubMed
  70. Thelin MA, et al. 2017. Diabetes. 66:2220. PubMed
  71. Zhang LJ, et al. 2019. Immunity. 50:121. PubMed
  72. Abels ER et al. 2019. Cell Rep. 28(12):3105-3119 . PubMed
  73. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  74. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  75. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  76. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  77. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  78. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  79. Rodrigues M, et al. 2022. Biochem J. 479:1891. PubMed
  80. Jung MY, et al. 2022. Neurooncol Adv. 4:vdac017. PubMed
  81. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  82. Di Martile M, et al. 2020. J Immunother Cancer. 8:. PubMed
  83. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  84. Li Z, et al. 2021. Immunology. 163:105. PubMed
  85. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  86. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  87. Gazit R, et al. 2014. J Exp Med. 211:1315. PubMed
  88. Kurelac I, et al. 2019. Nat Commun. 10:903. PubMed
  89. Kobayashi Y, et al. 2018. PLoS One. 13:e0195008. PubMed
  90. Delás MJ, et al. 2019. Cell Rep. 27:719. PubMed
  91. Wei H, et al. 2021. Malar J. 20:89. PubMed
  92. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  93. Hickey A, et al. 2021. Front Microbiol. 12:653587. PubMed
  94. Morgan PK, et al. 2021. J Biol Chem. 297:101341. PubMed
  95. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  96. Piepke M, et al. 2021. J Neuroinflammation. 18:265. PubMed
  97. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  98. Chen T, et al. 2021. JCI Insight. 6:. PubMed
  99. Radovanovic I, et al. 2014. J Immunol. 193:1290. PubMed
  100. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  101. Zheng W, et al. 2021. Wellcome Open Research. 6:52. PubMed
  102. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  103. Riether C, et al. 2021. Cell Reports. 34(4):108663. PubMed
  104. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  105. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
  106. Saggu G, et al. 2018. Nat Commun. 9:5058. PubMed
  107. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  108. Bowers E, et al. 2018. Nat Med. 24:95. PubMed
  109. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  110. Deslyper G, et al. 2021. Parasitology. 148:539. PubMed
  111. Shen H, et al. 2015. Infect Immun . 83: 2694 - 2704. PubMed
  112. Akhmetzyanova ER, et al. 2019. Front Cell Neurosci. 12:507. PubMed
  113. Lubkin A et al. 2019. Cell host & microbe. 25(3):463-470 . PubMed
  114. Gibson EM, et al. 2019. Cell. 176:43:00. PubMed
  115. Juttukonda LJ, et al. 2017. Cell Host Microbe. 22:531. PubMed
  116. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  117. Somerville TD, et al. 2020. eLife. 9:e53381.. PubMed
  118. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  119. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  120. Zong L, et al. 2021. NPJ Aging Mech Dis. 7:25. PubMed
  121. Almutairi F, et al. 2021. Front Immunol. 12:772288. PubMed
  122. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  123. Royzman D, et al. 2022. Front Immunol. 13:1012647. PubMed
  124. Martin R, et al. 2014. J Leukoc Biol. 96:151. PubMed
  125. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  126. Yamamoto K, et al. 2021. Cell Reports. 36(8):109576. PubMed
  127. Uroda T, et al. 2020. Nat Protoc. 15:2107. PubMed
  128. Sasaki K, et al. 2019. Nat Commun. 10:3878. PubMed
  129. Angelidis I, et al. 2019. Nat Commun. 10:963. PubMed
  130. Xu X, et al. 2021. J Nanobiotechnology. 19:376. PubMed
  131. Walker FC, et al. 2021. PLoS Pathog. 17:e1009402. PubMed
  132. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  133. Liu Y, et al. 2022. Nat Commun. 13:2665. PubMed
  134. Beauchamp EM, et al. 2021. Blood Cancer Discov. 6:. PubMed
  135. Dodagatta-Marri E, et al. 2021. Cell Rep. 36:109309. PubMed
  136. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
  137. Kulkarni NN, et al. 2021. J Biol Chem. 297:100828. PubMed
  138. Jia X, et al. 2021. Front Cell Dev Biol. 9:685522. PubMed
  139. Klopfenstein N, et al. 2021. PLoS Pathog. 17:e1009387. PubMed
  140. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  141. Vazquez S, et al. 2015. Exp Hematol. 43: 578-585. PubMed
  142. Shade K, et al. 2015. J Exp Med. 212:457. PubMed
  143. Vasilijevic J, et al. 2017. PLoS Pathog. 13:e1006650. PubMed
  144. Meeks K, et al. 2009. J Immunol. 183:8026. PubMed
  145. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  146. Wang L, et al. 2021. Cancer Immunol Res. 9:348. PubMed
  147. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  148. Shin JE, et al. 2021. Heliyon. 7:e08433. PubMed
  149. Koh F, et al. 2015. Proc Natl Acad Sci U S A. 112:1734. PubMed
  150. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  151. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  152. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  153. Snell LM, et al. 2018. Immunity. 49:678. PubMed
  154. Amo-Aparicio J, et al. 2021. Theranostics. 11:9805. PubMed
  155. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  156. Goldman E, et al. 2021. Cells. 10:. PubMed
  157. Dokoshi T, et al. 2021. J Clin Invest. 131:. PubMed
  158. Pan YC, et al. 2021. Mol Ther Oncolytics. 20:175. PubMed
  159. Aegerter H, et al. 2020. Nat Immunol. 0.975694444. PubMed
  160. Zhang S, et al. 2020. Front Immunol. 1.757638889. PubMed
  161. Kirschbaum K, et al. 2016. Proc Natl Acad Sci U S A. 113: 13227 - 13232. PubMed
  162. Kooreman NG et al. 2018. Cell stem cell. 22(4):501-513 . PubMed
  163. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  164. Secondini C, et al. 2017. Oncoimmunology. 6:e1316437. PubMed
  165. Huang YL, et al. 2021. Commun Biol. 4:229. PubMed
  166. Littwitz-Salomon E, et al. 2021. Nat Commun. 12:5376. PubMed
  167. Synn CB, et al. 2022. Clin Transl Immunology. 11:e1364. PubMed
  168. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  169. Gomzikova MO, et al. 2020. Sci Rep. 10:10740. PubMed
  170. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  171. Okubo K, et al. 2021. Cell Reports. 35(7):109142. PubMed
  172. Gozgit JM, et al. 2021. Cancer Cell. :. PubMed
  173. Suresh MV, et al. 2019. JCI Insight. 4:e133103. PubMed
  174. Patel S, et al. 2019. Viruses. 0.877083333. PubMed
  175. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  176. Kumar MP, et al. 2018. Cell Rep. 25:1458. PubMed
  177. Steuerman Y et al. 2018. Cell systems. 6(6):679-691 . PubMed
  178. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  179. Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
  180. Wang D, et al. 2021. Nat Commun. 12:2674. PubMed
  181. Jia Q, et al. 2021. Theranostics. 4699:11. PubMed
  182. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  183. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  184. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  185. Bambouskova M, et al. 2021. Cell Reports. 34(10):108756. PubMed
  186. Ringel AE, et al. 2020. Cell. 183(7):1848-1866.e26. PubMed
  187. Pérez-Girón J, et al. 2015. J Vis Exp. 100: 52803. PubMed
  188. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  189. Marcus A et al. 2018. Immunity. 49(4):754-763 . PubMed
  190. Van Winkle JA et al. 2018. Cell host & microbe. 24(5):665-676 . PubMed
  191. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  192. Wilson DH, et al. 2020. Nat Commun. 0.767361111. PubMed
  193. Tran NT, et al. 2020. STAR Protocols. 1(1):100028. PubMed
  194. Endoh M, et al. 2020. Cell Reports. 30(6):1823-1834. PubMed
  195. Li H, et al. 2020. Nature. 584:274. PubMed
  196. Sibilio A, et al. 2022. iScience. 25:103790. PubMed
  197. Dey S, et al. 2020. J Immunother Cancer. 8:. PubMed
  198. Shen M, et al. 2022. Nat Cancer. 3:60. PubMed
  199. Liu H, et al. 2022. Front Pharmacol. 13:949316. PubMed
  200. Boulay A, et al. 2015. J Neurosci. 35:4427. PubMed
  201. Trefzer A, et al. 2021. Cell Reports. 34(6):108748. PubMed
  202. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  203. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  204. Denny JE, et al. 2019. Sci Rep. 2.786111111. PubMed
  205. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  206. Simula L et al. 2018. Cell reports. 25(11):3059-3073 . PubMed
  207. Gao C, et al. 2017. Mol Neurobiol.. 10.1007/s12035-016-0318-0. PubMed
  208. Khare P, et al. 2017. J Autoimmun. 10.1016/j.jaut.2017.09.002. PubMed
  209. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  210. Frenis K, et al. 2021. Basic Res Cardiol. 31:116. PubMed
  211. Crouse B, et al. 2020. NPJ Vaccines. 0.277083333. PubMed
  212. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  213. Arce-Cerezo A, et al. 2015. Sci Rep. 5: 1448. PubMed
  214. Ballet R, et al. 2014. PLoS Pathog. 10:1004550. PubMed
  215. Robinett RA et al. 2018. Cell systems. 7(1):41-48 . PubMed
  216. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  217. Mohamed E, et al. 2020. Immunity. 52(4):668-682.e7.. PubMed
  218. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  219. Merrell AJ, et al. 2021. Hepatology. 74:444. PubMed
  220. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  221. Yu W, et al. 2022. Nat Commun. 13:3544. PubMed
  222. Scholz F, et al. 2015. J Immunol. 195: 2335-2342. PubMed
  223. Koelwyn GJ, et al. 2020. Nat Med. 1452:26. PubMed
  224. Kim SJ, et al. 2020. Cell Mol Immunol. 17:728. PubMed
  225. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  226. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  227. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  228. Zhang CR, et al. 2022. Blood Cancer Discov. 3:220. PubMed
  229. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  230. Wang S, et al. 2021. Commun Biol. 22:. PubMed
  231. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  232. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  233. Bent EH, et al. 2021. Nat Commun. 12:6218. PubMed
  234. Nahrendorf W, et al. 2021. eLife. 10:00. PubMed
  235. Mansouri S, et al. 2020. Mucosal Immunol. 0.954861111. PubMed
  236. Sasaki Y, et al. 2015. PLoS One. 10: 0131176. PubMed
  237. Celik H, et al. 2018. Cancer Cell. 34:741. PubMed
  238. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  239. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  240. Ivan DC, et al. 2021. Front Immunol. 12:666961. PubMed
  241. Franklin DA, et al. 2020. JCI Insight. 5:. PubMed
  242. Omatsu Y, et al. 2022. Nat Commun. 13:2654. PubMed
  243. Liu W, et al. 2022. J Clin Invest. 132: . PubMed
  244. Schönberger K, et al. 2022. STAR Protoc. 3:101408. PubMed
  245. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  246. Calderon B, et al. 2015. J Exp Med. 212: 1497-1512. PubMed
  247. Richardson ET, et al. 2015. PLoS One. 10: 1371. PubMed
  248. Moro T, et al. 2016. PLoS One. 11: 0146592. PubMed
  249. Kobia FM, et al. 2020. PLoS Biol. 18:e3000850. PubMed
  250. Bordas M, et al. 2020. Int J Mol Sci. 21:00. PubMed
  251. Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
  252. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  253. Onai N, et al. 2020. Int J Mol Sci. :22. PubMed
  254. Beauchamp N, et al. 2010. J Virol. 84:10191. PubMed
  255. Wang Y, et al. 2020. eLife. 9:e57438.. PubMed
  256. Yu L, et al. 2020. Nat Commun. 2.045833333. PubMed
  257. McKenzie MD, et al. 2019. Cell Stem Cell. 25:258. PubMed
  258. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  259. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  260. Cantor DJ et al. 2019. Cell reports. 26(1):108-118 . PubMed
  261. Baratin M, et al. 2017. Immunity. 47:349. PubMed
  262. Coley WD et al. 2018. F1000Research. 2018 Mar 14 [revised 2018 Jan 1] 0.5125. PubMed
  263. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  264. Sadhu S, et al. 2021. J Immunol. 207:1812. PubMed
  265. Sun L, et al. 2022. Adv Sci (Weinh). 9:e2104051. PubMed
  266. Canedo T, et al. 2021. Neuropsychopharmacology. 46:2358. PubMed
  267. Johnson RM, et al. 2021. Front Immunol. 11:614697. PubMed
  268. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  269. Gourvest M, et al. 2021. Leukemia. . PubMed
  270. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  271. Gicheva N, et al. 2016. Biochem Biophys Res Commun. 479:1-4. PubMed
  272. Asada S, et al. 2018. Nat Commun. 9:2733. PubMed
  273. Kong XF, et al. 2018. Nat Immunol. 19:973. PubMed
  274. Rosen DA, et al. 2019. Sci Transl Med. 11:eaau5266. PubMed
  275. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  276. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  277. Süß P, et al. 2020. Cell Reports. 30(12):4082-4095. PubMed
  278. Shi J, et al. 2022. Front Pharmacol. 12:818326. PubMed
  279. McPhee C, et al. 2013. J Immunol. 191:4581. PubMed
  280. Fujimura N, et al. 2016. Sci Rep. 5:11664. PubMed
  281. Tsunekuni K, et al. 2020. J Clin Med. 9:00. PubMed
  282. Huang WC, et al. 2020. Adv Mater. 32:e2005637. PubMed
  283. Shin M, et al. 2020. Cell Chem Biol. 314:27. PubMed
  284. Kaiser S, et al. 2020. Glia. 68:2427. PubMed
  285. Aggio-Bruce R, et al. 2020. Mol Neurobiol. . PubMed
  286. Santopaolo M, et al. 2021. Front Immunol. 609406:12. PubMed
  287. Molgora M, et al. 2020. Cell. 182:886. PubMed
  288. Alfaro M, et al. 2008. Proc Natl Acad Sci U S A. 105:18366. PubMed
  289. Walker JA, et al. 2020. Immunity. 51(1):104-118. PubMed
  290. Winter C, et al. 2018. Cell Metab. 28:175. PubMed
  291. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  292. Liu G, et al. 2022. Theranostics. 12:2248. PubMed
  293. Fan HH, et al. 2021. Methods Mol Biol. 2276:203. PubMed
  294. Monteiro LB, et al. 2020. MethodsX. 7:100938. PubMed
  295. Rodriguez-Tirado C, et al. 2022. Cancers (Basel). 14:. PubMed
  296. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  297. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  298. Chavez JS, et al. 2022. Cells. 11:. PubMed
  299. Boulch M, et al. 2021. Sci Immunol. 6:. PubMed
  300. Gao P, et al. 2020. Front Immunol. 1.636111111. PubMed
  301. Chen S, et al. 2015. Cancer Res . 7: 519-531. PubMed
  302. Groppa E, et al. 2015. EMBO Mol Med. 2015; 7: 1366 - 1384. PubMed
  303. Gharib S, et al. 2014. J Leukoc Biol. 95:9. PubMed
  304. Saul S, et al. 2019. J Leukoc Biol. N/A. PubMed
  305. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
  306. Boguslawski KM, et al. 2020. Sci Adv. 6:eaax7515. PubMed
  307. Wang L, et al. 2020. J Nanobiotechnology. 18:38. PubMed
  308. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  309. Franklin R, et al. 2022. Nat Commun. 13:2350. PubMed
  310. Gawish R, et al. 2022. Elife. 11:. PubMed
  311. Akhand SS, et al. 2020. Cancer Immunol Res. 8:1542. PubMed
  312. Xu G, et al. 2015. Free Radic Biol Med. 87: 15-25. PubMed
  313. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  314. Maas SLN, et al. 2020. J Neuroinflammation. 17:120. PubMed
  315. Qi S, et al. 2020. Theranostics. 10:1814. PubMed
  316. Zheng W, et al. 2019. Cell Rep. 29:1747. PubMed
  317. Lalor R, et al. 2019. Nutrients. 11. PubMed
  318. Cai T, et al. 2022. Front Immunol. 13:1009932. PubMed
  319. Scheyltjens I, et al. 2022. Nat Protoc. 17:2354. PubMed
  320. Zhang Y, et al. 2022. J Immunother Cancer. 10:. PubMed
  321. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  322. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  323. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  324. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  325. Young K, et al. 2021. Cell Stem Cell. . PubMed
  326. Lucas ED, et al. 2020. Cell Reports. 33(2):108258. PubMed
  327. Zysset D, et al. 2016. Nat Commun. 7:13151. PubMed
  328. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
RRID
AB_312798 (BioLegend Cat. No. 101215)
AB_312798 (BioLegend Cat. No. 101216)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
CD11b
Specificity Alt (DOES NOT SHOW ON TDS):
CD11b
App Abbreviation (DOES NOT SHOW ON TDS):
FC
UniProt
View information about CD11b on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
PE/Fire™ 744 anti-mouse/human CD11b M1/70 FC
Spark PLUS UV395™ anti-mouse/human CD11b M1/70 FC
Spark Red™ 718 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account