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APC anti-mouse CD11c Antibody

Pricing & Availability
Clone
N418 (See other available formats)
Regulatory Status
RUO
Other Names
αX integrin, integrin αX chain, CR4, p150, ITGAX
Isotype
Armenian Hamster IgG
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Product Citations
publications
N418
C57BL/6 mouse splenocytes stained with N418 APC and PK136 PE
  • N418
    C57BL/6 mouse splenocytes stained with N418 APC and PK136 PE
Compare all formats See APC spectral data
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117309 25 µg 27€
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117310 100 µg 93€
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Description

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse spleen dendritic cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11c antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9 (Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.

Application References

(PubMed link indicates BioLegend citation)
  1. Granucci F, et al. 1997. J. Immunol. 159:1794.
  2. Stokes RW, et al. 1998. J. Immunol. 160:5514.
  3. Metlay JP, et al. 1990. J. Exp. Med. 171:1753. (IHC, IP)
  4. Ma XT, et al. 2006. Cancer Research 66:1169.
  5. Chin RK, et al. 2006. J. Immunol. 177:290. (IF)
  6. Cervantes-Barragan L, et al. 2007. Blood 109:1131. (FC) PubMed
  7. Turnquist HR, et al. 2007. J. Immunol. 178:7018. (FC) PubMed
  8. Benson MJ, et al. 2007. J. Exp. Med. doi:10.1084/jem.20070719. (FC) PubMed
  9. You Y, et al. 2009. J. Immunol. 182:7343. (IF) PubMed
  10. Roland CL, et al. 2009. Mol. Cancer Res. 8:1761. (IHC, FC) PubMed
  11. Wikstrom M, et al.2006. J. Immunol. 177:913. PubMed
  12. Pericolini E, et al. 2008. J. Leukocyte Biol. 83:1286. PubMed
  13. Randall LM, et al. 2008. Infect. Immun.76:3312. PubMed
  14. Fahlen-Yrild L, et al. 2009. J. Immunol. 183:5032. PubMed
  15. Osterholzer JJ, et al. 2009. J. Immunol. 183:8044. PubMed
  16. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed
  17. Eisenach PA, et al. 2010. J Cell Sci. 123:4182. PubMed
  18. Leppin K, et al. 2014. Invest. Ophthalmol. Vis. Sci. 55:3603. PubMed
  19. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  20. Gibbins JD, et al. 2014. Blood. 124:2953. PubMed
  21. White CE, et al. 2015. J Immunol. 194:697. PubMed
  22. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  23. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  24. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  2. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  3. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  4. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  5. Minute L, et al. 2020. J Immunother Cancer. 8:. PubMed
  6. Xue G, et al. 2021. Cancer Cell. 39:1610. PubMed
  7. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  8. Xin B, et al. 2022. Hepatology. 76:630. PubMed
  9. Huis In 't Veld LGM, et al. 2022. Cell Mol Life Sci. 79:231. PubMed
  10. Chae CS, et al. 2022. Cancer Discov. 12:1904. PubMed
  11. Minichino D, et al. 2022. J Leukoc Biol. 112:1089. PubMed
  12. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  13. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  14. Liu Z, et al. 2022. Cancer Commun (Lond). 42:971. PubMed
  15. Chen C, et al. 2022. Sci Adv. 8:eabo4363. PubMed
  16. Guasconi L, et al. 2022. J Fungi (Basel). 8: . PubMed
  17. McAlpine CS, et al. 2022. J Exp Med. 219: . PubMed
  18. Zhu J, et al. 2022. Research (Wash D C). 2022:9816272. PubMed
  19. Klaus T, et al. 2022. JCI Insight. 7: . PubMed
  20. Chen Y, et al. 2023. Adv Healthc Mater. 12:e2202085. PubMed
  21. Kraemer AN, et al. 2022. Front Immunol. 13:933191. PubMed
  22. Fan R, et al. 2023. J Immunother Cancer. 11: . PubMed
  23. Taniguchi S, et al. 2023. Nat Commun. 14:143. PubMed
  24. Wang D, et al. 2023. J Exp Clin Cancer Res. 42:26. PubMed
  25. Zhao X, et al. 2022. Cell Mol Immunol. 19:540. PubMed
  26. Duan H, et al. 2022. Adv Sci (Weinh). 9:e2103719. PubMed
  27. Michalaki C, et al. 2022. Curr Protoc. 2:e505. PubMed
  28. Narusawa M, et al. 2014. Cancer Immunol Res. 2:568. PubMed
  29. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  30. Lin C, et al. 2020. Cancer Immunol Res. 632:8. PubMed
  31. Ramakrishna C, et al. 2019. Nat Commun. 10:2153. PubMed
  32. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  33. Kawabe T, et al. 2020. Nat Commun. 2.795833333. PubMed
  34. Akhtar MN, et al. 2022. MBio. 13:e0330921. PubMed
  35. Sauter M, et al. 2022. STAR Protoc. 3:101664. PubMed
  36. Sia ZR, et al. 2022. J Virol. 96:e0100622. PubMed
  37. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  38. Tan J, et al. 2023. Acta Pharm Sin B. 13:632. PubMed
  39. Shi X, et al. 2023. iScience. 26:106143. PubMed
  40. Pasqual G, et al. 2023. Methods Mol Biol. 2618:71. PubMed
  41. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  42. Seclì L, et al. 2023. J Immunother Cancer. 11:. PubMed
  43. Li Y, et al. 2023. Front Cell Infect Microbiol. 13:1117230. PubMed
  44. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  45. Wang D, et al. 2023. Nat Commun. 14:2943. PubMed
  46. Song J, et al. 2023. iScience. 26:106753. PubMed
  47. Song S, et al. 2023. Bioact Mater. 28:358. PubMed
  48. Kitai H, et al. 2022. BMC Biol. 20:248. PubMed
  49. Tan L, et al. 2022. Biochem Biophys Rep. 32:101351. PubMed
  50. Li Q, et al. 2022. Cell Rep. 40:111308. PubMed
  51. Lefebvre MN, et al. 2021. Cell Rep. 37:109956. PubMed
  52. Jiang Q, et al. 2022. Theranostics. 12:59. PubMed
  53. Zhou J, et al. 2021. Int J Med Sci. 18:3516. PubMed
  54. Meng W, et al. 2021. JCI Insight. 6:. PubMed
  55. Miller CM, et al. 2020. J Virol. 94:00:00. PubMed
  56. Gujar R, et al. 2016. J Immunol. 197: 1650 - 1662. PubMed
  57. Nocera D, et al. 2016. J Immunol. 196: 2860 - 2869. PubMed
  58. Riva A, et al. 2013. J Immunol. 190:5961. PubMed
  59. Zhang LJ, et al. 2019. Immunity. 50:121. PubMed
  60. Shi L, et al. 2019. Theranostics. 9:4115. PubMed
  61. Page N, et al. 2018. Immunity. 48:937. PubMed
  62. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  63. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  64. Pandey S, et al. 2020. Cell Syst. 11:495. PubMed
  65. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  66. Sauter M, et al. 2022. iScience. 25:103677. PubMed
  67. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  68. Xia S, et al. 2014. J Leukoc Biol. 95:733. PubMed
  69. Aguilera T, et al. 2016. Nat Commun. 7:13898. PubMed
  70. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  71. Kim TJ, et al. 2019. Nat Commun. 10:3258. PubMed
  72. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  73. Kunimura K, et al. 2020. Cell Reports. 29(9):2823-2834.e7.. PubMed
  74. Liang W, et al. 2022. Methods Mol Biol. 2574:221. PubMed
  75. Wiernicki B, et al. 2022. Nat Commun. 13:3676. PubMed
  76. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  77. Chen WS, et al. 2021. Cell Rep. 37:109974. PubMed
  78. Klarquist J, et al. 2021. Cell Rep. 36:109591. PubMed
  79. Nam J, et al. 2021. Adv Sci (Weinh). 2002577:8. PubMed
  80. de Mingo Pulido , et al. 2021. Immunity. 54(6):1154-1167.e7. PubMed
  81. Coppo M, et al. 2016. Nat Commun. 7:12254. PubMed
  82. Wegmann F, et al. 2015. Clin Vaccine Immunol. 22: 1004-1012. PubMed
  83. Qian F, et al. 2015. J Mol Cell Biol. . PubMed
  84. He Y, et al. 2020. Sci Adv. 6:eaba7589. PubMed
  85. Blumenthal D, et al. 2020. eLife. 9:e55995.. PubMed
  86. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  87. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  88. Shin M et al. 2019. Cell Chem Biol. 26(7):1036-1041 . PubMed
  89. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  90. Zhao J, et al. 2019. Nat Commun. 10:899. PubMed
  91. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  92. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  93. Wiede F, et al. 2021. Cancer Discov. Online ahead of print. PubMed
  94. Zhou HF, et al. 2022. Front Pharmacol. 13:778755. PubMed
  95. Helm M, et al. 2022. Life (Basel). 12:. PubMed
  96. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  97. Prado C, et al. 2012. J Immunol. 188:3062. PubMed
  98. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  99. Bode K, et al. 2020. Cell Reports. 29(13):4435-4446.e9.. PubMed
  100. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  101. Hao F, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  102. Kulkarni NN, et al. 2021. J Biol Chem. 297:100828. PubMed
  103. Yu AI, et al. 2020. Cell Rep. 107471:31. PubMed
  104. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  105. O'Shea NR, Chew TS 2016. J Crohns Colitis. 10(12):1417-1427. PubMed
  106. Angelidis I, et al. 2019. Nat Commun. 10:963. PubMed
  107. Cao W, et al. 2017. Immunity. 47:1182. PubMed
  108. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  109. Sharma PK, et al. 2018. Cancer Gene Ther. 25:27. PubMed
  110. Yuan B, et al. 2021. J Immunother Cancer. 9:. PubMed
  111. Jing L, et al. 2022. Front Immunol. 13:864995. PubMed
  112. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  113. Wang B, et al. 2022. Nat Commun. 13:3821. PubMed
  114. Dos Santos Dias L, et al. 2021. PLoS Pathog. e1009324:17. PubMed
  115. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  116. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  117. Lin SY, et al. 2017. Autophagy. 14:778. PubMed
  118. McAlpine CS, et al. 2021. Nature. 595:701. PubMed
  119. Stump CT, et al. 2021. Open Biol. 11:210245. PubMed
  120. Dokoshi T, et al. 2021. J Clin Invest. 131:. PubMed
  121. Marjanovic ND, et al. 2020. Cancer Cell. 38(2):229-246.e13. PubMed
  122. Wang Y, et al. 2021. Sci Rep. 1.429861111. PubMed
  123. Sellau J, et al. 2016. Sci Rep. 6:28058. PubMed
  124. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  125. Madan-Lala R, et al. 2014. J Immunol. 192:4263. PubMed
  126. Bunn P, et al. 2014. J Immunol. 192:3709. PubMed
  127. Ustarroz-Cano M, et al. 2012. J Immunotoxicol. 9:374. PubMed
  128. Bak S, et al. 2008. Mol Immunol. 45:1414. PubMed
  129. Bertino P, et al. 2019. Oncoimmunology. 8:1601482. PubMed
  130. Lisk C, et al. 2020. Front Immunol. 1.329166667. PubMed
  131. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  132. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  133. Liu D et al. 2019. Immunity. 51(1):64-76 . PubMed
  134. Matsumura T et al. 2019. Cell Rep. 27(2):561-571 . PubMed
  135. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  136. Suryawanshi RK, et al. 2021. Nat Commun. 12:6020. PubMed
  137. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  138. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  139. Cho YK, et al. 2022. Nat Commun. 13:4084. PubMed
  140. Zou J, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:983. PubMed
  141. Li W, et al. 2021. Front Pharmacol. 12:697483. PubMed
  142. Glauser D, et al. 2013. J Virol. 87:10828. PubMed
  143. Aebischer D, et al. 2014. PLoS One. 9:99297. PubMed
  144. Spinner C, et al. 2015. Sci Rep. 5:16269. PubMed
  145. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  146. Li N, et al. 2021. eLife. 10:00. PubMed
  147. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  148. Gozgit JM, et al. 2021. Cancer Cell. :. PubMed
  149. Kooreman NG et al. 2018. Cell stem cell. 22(4):501-513 . PubMed
  150. Xu H, et al. 2020. Immunity. 51(4):696-708.e9.. PubMed
  151. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  152. Zhang C, et al. 2022. Nat Commun. 13:3468. PubMed
  153. Xu M, et al. 2022. Genes Dis. 9:429. PubMed
  154. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  155. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  156. Liu M, et al. 2016. PLoS One. 11:e0166165. PubMed
  157. Markey K, et al. 2014. J Immunol. 192:5426. PubMed
  158. Cheng Y, et al. 2020. PLoS Pathog. 16:e1008569. PubMed
  159. Dmitrieva‐Posocco O et al. 2019. Immunity. 50(1):166-180 . PubMed
  160. Yadava K et al. 2019. Elife. 8 pii: e44821. PubMed
  161. Garo LP, et al. 2019. Cell Rep. 28:3353. PubMed
  162. Budida R, et al. 2017. Eur J Immunol. 47:1819. PubMed
  163. Niknam S, et al. 2018. Clin Cancer Res. 24:5735. PubMed
  164. Miteva K, et al. 2018. Sci Rep. 8:2820. PubMed
  165. Yang Y, et al. 2021. Sci Adv. 7:eabf6290. PubMed
  166. Kim S, et al. 2021. Elife. 10:. PubMed
  167. Gibbins J, et al. 2014. Blood. 124:2953. PubMed
  168. White C, et al. 2015. J Immunol. 194:697. PubMed
  169. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  170. Wanner-Seleznik GM, et al. 2020. Immunohorizons. 0.644444444. PubMed
  171. Liu Z, et al. 2021. Immunity. 54(2):247-258.e7. PubMed
  172. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  173. Zeng W, et al. 2021. STAR Protocols. 2(1):100361. PubMed
  174. Platteel A, et al. 2017. Vaccine.. 10.1016/j.vaccine.2017.10.044. PubMed
  175. Hu J, et al. 2019. Mol Ther Nucleic Acids. 16:650. PubMed
  176. He J, et al. 2019. J Clin Invest. 130. PubMed
  177. Kemp V, et al. 2018. Cancer Gene Ther. 26:268. PubMed
  178. Kramer K, et al. 2017. ACS Omega. 0.240972222. PubMed
  179. Liu W, et al. 2019. Epigenetics. 1.192361111. PubMed
  180. Marsh L, et al. 2009. Am J Physiol Lung Cell Mol Physiol. 296:L442. PubMed
  181. Lang V, et al. 2021. Elife. 10:. PubMed
  182. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  183. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  184. Li C, et al. 2021. Cell Metabolism. 33(8):1610-1623.e5. PubMed
  185. Dobson HE, et al. 2020. Mucosal Immunol. 0.901388889. PubMed
  186. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  187. Mainini F, et al. 2015. PLoS One. 10: 0145403. PubMed
  188. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  189. Liu Z, et al. 2020. Cell. 178(6):1509-1525.e19.. PubMed
  190. Yahagi A, et al. 2019. RMD Open. 5:e000853. PubMed
  191. Xia P et al. 2018. Immunity. 48(4):688-701 . PubMed
  192. Nam GH, et al. 2018. Nat Commun. 9:2165. PubMed
  193. Fischer FA, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  194. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  195. Tukaramrao DB, et al. 2021. Cancers (Basel). 13:. PubMed
  196. Wüthrich M, et al. 2021. MBio. 12:e0201821. PubMed
  197. Schneider KM, et al. 2022. Nat Commun. 13:3964. PubMed
  198. Kohn EM, et al. 2022. J Immunol. 208:1417. PubMed
  199. Wang Y, et al. 2022. J Control Release. 349:118. PubMed
  200. Takaki H, et al. 2013. J Immunol. 191:4740. PubMed
  201. Wang H, et al. 2020. Nat Mater. 1.655555556. PubMed
  202. Ye Y, et al. 2017. Sci Immunol. 2:17. PubMed
  203. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  204. Trinh HKT, et al. 2019. J Cell Mol Med. 23:3441. PubMed
  205. Tang Z, et al. 2021. Stem Cell Res Ther. 12:397. PubMed
  206. Zhang XW, et al. 2021. Oncoimmunology. 10:1920739. PubMed
  207. Li X, et al. 2021. Cell Death Dis. 12:314. PubMed
  208. Shan B, et al. 2020. Nat Metab. 1332:2. PubMed
  209. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  210. Peng X, et al. 2016. J Cell Sci. 129: 1831 - 1842. PubMed
  211. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  212. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  213. Chitu V, et al. 2020. Cell Reports. 30(9):3004-3019. PubMed
  214. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  215. Yamada S, et al. 2018. Arterioscler Thromb Vasc Biol. 38:994. PubMed
  216. Chu LH, et al. 2018. Nat Commun. 9:996. PubMed
  217. Carlson PM, et al. 2021. J Immunol. 207:720. PubMed
  218. Woodring T, et al. 2022. iScience. 25:104934. PubMed
  219. Berthold N, et al. 2013. Antimicrob Agents Chemother. 57:402. PubMed
  220. Upadhya R, et al. 2016. MBio. 7: 00547-16. PubMed
  221. Onai N, et al. 2020. Int J Mol Sci. :22. PubMed
  222. Li C, et al. 2018. Cell. 174:285. PubMed
  223. Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
  224. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  225. Qian Z, et al. 2022. Biomedicines. 10:. PubMed
  226. Bezu L, et al. 2022. J Immunother Cancer. 10:. PubMed
  227. Huang T, et al. 2022. Nat Commun. 13:3489. PubMed
  228. Vogel A, et al. 2022. Cell Rep. 38:110420. PubMed
  229. Sebina I, et al. 2016. PLoS Pathog. 12:e1005999. PubMed
  230. Zhao W, et al. 2014. Clin Vaccine Immunol. 21:74. PubMed
  231. McCauley ME, et al. 2020. Nature. 585(7823):96-101. PubMed
  232. Jiang Y, et al. 2021. Nat Commun. 12:742. PubMed
  233. Lisk C, et al. 2021. Front Immunol. 12:624197. PubMed
  234. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  235. Takahashi N, et al. 2022. Tohoku J Exp Med. 257:171. PubMed
  236. Grube J, et al. 2022. Cell Death Dis. 13:704. PubMed
  237. Liu Q, et al. 2021. Adv Mater. 33:e2102852. PubMed
  238. Sobecki M, et al. 2022. Cell Stem Cell. 29:1459. PubMed
  239. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  240. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  241. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  242. Kramer K, et al. 2017. Mol Ther. 25(1):62-70. PubMed
  243. Yin X, et al. 2020. Cell Rep. 33:108278. PubMed
  244. Huang WC, et al. 2020. Adv Mater. 32:e2005637. PubMed
  245. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  246. Wang S, et al. 2020. J Cell Mol Med. 24:722. PubMed
  247. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  248. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  249. Dye BR, et al. 2020. Biomaterials. 234:119757. PubMed
  250. Shen H, et al. 2022. Nat Commun. 13:5013. PubMed
  251. Smith LK, et al. 2021. Elife. 10:. PubMed
  252. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  253. Li H, et al. 2022. iScience. 25:104481. PubMed
  254. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  255. Boulch M, et al. 2021. Sci Immunol. 6:. PubMed
  256. Nicholls J, et al. 2021. Front Cell Dev Biol. 9:737880. PubMed
  257. Huang WC, et al. 2020. NPJ Vaccines. 5:23. PubMed
  258. Ryu S, et al. 2021. eLife. 0.416666666666667. PubMed
  259. Wang Y, et al. 2021. Nat Commun. 0.570833333. PubMed
  260. Aguilera TA, et al. 2020. Clin Cancer Res. 26:2972. PubMed
  261. Martins R, et al. 2016. Nat Immunol. 17:1361-1372. PubMed
  262. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  263. Huang WC, et al. 2020. NPJ Vaccines. 5:23. PubMed
  264. Kunishita Y, et al. 2020. Front Immunol. 11:98. PubMed
  265. Wang C, et al. 2018. Sci Transl Med. 10. PubMed
  266. Zhang B, et al. 2021. Nature. 599:471. PubMed
  267. Wang X, et al. 2021. Sci Transl Med. 13:. PubMed
  268. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  269. Gawish R, et al. 2022. Elife. 11:. PubMed
  270. Gentschev I, et al. 2012. PLoS One. 7:e37239. PubMed
  271. Dyer DP et al. 2019. Immunity. 50(2):378-389 . PubMed
  272. Sadtler K, et al. 2017. Tissue Eng Part A. 23:1044. PubMed
  273. Matisz CE, et al. 2018. Am J Pathol. 188:2589. PubMed
  274. Hong Y, et al. 2019. J Extracell Vesicles. 8:1670893. PubMed
  275. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  276. Yu L, et al. 2022. Front Immunol. 13:937331. PubMed
  277. Sethuraman SN, et al. 2020. Theranostics. 10:3397. PubMed
  278. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  279. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  280. Akhtar MN, et al. 2020. PLoS Pathog. 16:e1009136. PubMed
  281. Shi GN, et al. 2021. Ther Adv Med Oncol. 13:1758835920987056. PubMed
  282. Rana MN, et al. 2021. Front Pharmacol. 12:643215. PubMed
  283. Cortez MA, et al. 2020. Nat Commun. 3.819444444. PubMed
  284. Brenner E, et al. 2020. Nat Commun. 11:1335. PubMed
  285. Morrissey MA, et al. 2018. Elife. 7:e36688. PubMed
  286. Kubli SP, et al. 2019. Nat Commun. 10:2678. PubMed
  287. Yáñez A et al. 2017. Immunity. 47(5):890-902 . PubMed
RRID
AB_313778 (BioLegend Cat. No. 117309)
AB_313778 (BioLegend Cat. No. 117310)

Antigen Details

Structure
Integrin α-chain, associates with integrin β2 (CD18), 150 kD
Distribution

Dendritic cells, NK cells, intestinal intraepithelial lymphocytes (IEL), some activated T cells

Function
Cellular adhesion
Ligand/Receptor
iC3b, fibrinogen
Cell Type
Dendritic cells, Epithelial cells, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen Facts Book Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lopez-Rodriguez C, et al. 1996. J. Immunol. 156:3780.

Gene ID
16411 View all products for this Gene ID
UniProt
View information about CD11c on UniProt.org

Other Formats

View All CD11c Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD11c N418 FC
Biotin anti-mouse CD11c N418 FC,IHC-F
FITC anti-mouse CD11c N418 FC
PE anti-mouse CD11c N418 FC
Purified anti-mouse CD11c N418 FC,CyTOF®,IP,IHC
Alexa Fluor® 488 anti-mouse CD11c N418 FC
Alexa Fluor® 647 anti-mouse CD11c N418 FC,IHC,ICC,3D IHC
PE/Cyanine5 anti-mouse CD11c N418 FC
PE/Cyanine7 anti-mouse CD11c N418 FC
Brilliant Violet 605™ anti-mouse CD11c N418 FC
Alexa Fluor® 700 anti-mouse CD11c N418 FC
Pacific Blue™ anti-mouse CD11c N418 FC
APC/Cyanine7 anti-mouse CD11c N418 FC
PerCP/Cyanine5.5 anti-mouse CD11c N418 FC
PerCP anti-mouse CD11c N418 FC
Brilliant Violet 421™ anti-mouse CD11c N418 FC,IHC
Brilliant Violet 570™ anti-mouse CD11c N418 FC
Brilliant Violet 785™ anti-mouse CD11c N418 FC
Brilliant Violet 510™ anti-mouse CD11c N418 FC
Brilliant Violet 650™ anti-mouse CD11c N418 FC
Purified anti-mouse CD11c (Maxpar® Ready) N418 FC,CyTOF®
Alexa Fluor® 594 anti-mouse CD11c N418 IHC-F,3D IHC
PE/Dazzle™ 594 anti-mouse CD11c N418 FC
Brilliant Violet 711™ anti-mouse CD11c N418 FC
APC/Fire™ 750 anti-mouse CD11c N418 FC
TotalSeq™-A0106 anti-mouse CD11c N418 PG
Brilliant Violet 750™ anti-mouse CD11c N418 FC
TotalSeq™-B0106 anti-mouse CD11c N418 PG
TotalSeq™-C0106 anti-mouse CD11c N418 PG
KIRAVIA Blue 520™ anti-mouse CD11c N418 FC
Spark Blue™ 550 anti-mouse CD11c N418 FC
Spark NIR™ 685 anti-mouse CD11c N418 FC
Spark UV™ 387 anti-mouse CD11c N418 FC
Spark Red™ 718 anti-mouse CD11c N418 FC
Spark Blue™ 515 anti-mouse CD11c N418 FC
PerCP/Fire™ 806 anti-mouse CD11c N418 FC
Spark PLUS UV395™ anti-mouse CD11c N418 FC
Spark Blue™ 574 anti-mouse CD11c (Flexi-Fluor™) N418 FC
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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