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PerCP/Cyanine5.5 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
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Product Citations
publications
M1slash70_PerCPCyanine55_CD11b_Antibody_111918
C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
  • M1slash70_PerCPCyanine55_CD11b_Antibody_111918
    C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
Compare all formats See PerCP/Cyanine5.5 spectral data
Cat # Size Price Quantity Check Availability Save
101227 25 µg 90 CHF
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101228 100 µg 292 CHF
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Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11b antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Lee T, et al. 2014. Mol Biol Cell. 25:583. PubMed
  2. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  3. Orberg E, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.53. PubMed
  4. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  5. Milasan A, et al. 2017. J Am Heart Assoc. 10.1161/JAHA.117.006892. PubMed
  6. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  7. Lang J, et al. 2020. Nat Commun. 11:1338. PubMed
  8. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  9. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  10. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  11. Grandjean CL, et al. 2021. Sci Adv. 7:. PubMed
  12. Leslie J, et al. 2021. Sci Rep. 11:1415. PubMed
  13. Zheng J, et al. 2022. Front Pharmacol. 13:866228. PubMed
  14. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  15. Tian WJ, et al. 2021. Clin Exp Pharmacol Physiol. 48:902. PubMed
  16. Ferrao Blanco MN, et al. 2022. Br J Pharmacol. 179:2771. PubMed
  17. Osokine I, et al. 2022. Cell Rep. 38:110329. PubMed
  18. Agarwalla P, et al. 2022. Nat Biotechnol. 40:1250. PubMed
  19. Chae CS, et al. 2022. Cancer Discov. 12:1904. PubMed
  20. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  21. Marquardt RM, et al. 2022. Int J Mol Sci. 23: . PubMed
  22. Halin C, et al. 2022. EMBO J. 41:e111528. PubMed
  23. Auguste YSS, et al. 2022. Nat Neurosci. 25:1273. PubMed
  24. Schepers M, et al. 2023. Brain Behav Immun. 109:1. PubMed
  25. García-García A, et al. 2023. Bioact Mater. 24:174. PubMed
  26. Glaubitz J, et al. 2023. Gut. :. PubMed
  27. Zhang K, et al. 2023. Nat Metab. 5:129. PubMed
  28. Arimoto KI, et al. 2023. Nat Commun. 14:251. PubMed
  29. Zhang B, et al. 2023. Signal Transduct Target Ther. 8:28. PubMed
  30. Lazure F, et al. 2023. Nat Commun. 14:535. PubMed
  31. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  32. Meng S, et al. 2023. Stem Cell Investig. 10:2. PubMed
  33. Drummer C, et al. 2023. Front Immunol. 14:1113883. PubMed
  34. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  35. Wilden A, et al. 2022. Front Immunol. 13:991295. PubMed
  36. Peng W, et al. 2022. Cell Mol Life Sci. 79:602. PubMed
  37. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  38. Zhu S, et al. 2023. J Nanobiotechnology. 21:81. PubMed
  39. Guo D, et al. 2023. Cell Biosci. 13:51. PubMed
  40. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  41. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  42. Shen Z, et al. 2023. iScience. 26:106572. PubMed
  43. Haensel D, et al. 2023. Nat Commun. 14:2685. PubMed
  44. McNamara HA, et al. 2020. Cell Host Microbe. 572:28. PubMed
  45. Bouchareychas L, et al. 2021. iScience. 24(8):102847. PubMed
  46. Gern BH, et al. 2021. Cell Host Microbe. 29(4):594-606.e6. PubMed
  47. Kaczanowska S, et al. 2021. Cell. 184(8):2033-2052.e21. PubMed
  48. John S, et al. 2020. Sci Rep. 10:11377. PubMed
  49. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  50. Kim SS, et al. 2022. Cancers (Basel). 14:. PubMed
  51. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  52. Huang X, et al. 2021. Stem Cells Int. 2021:8138374. PubMed
  53. Hong M, et al. 2021. Int J Mol Sci. 22:. PubMed
  54. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  55. Zhao X, et al. 2022. Front Mol Biosci. 9:786864. PubMed
  56. Meng W, et al. 2021. JCI Insight. 6:. PubMed
  57. Ortiz G, et al. 2020. Front Immunol. 11:1713. PubMed
  58. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  59. Leach SM, et al. 2020. Cell Rep. 33:108337. PubMed
  60. Dong L, et al. 2021. Cancer Cell. . PubMed
  61. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  62. Fu B et al. 2017. Immunity. 47(6):1100-1113 . PubMed
  63. Chen L, et al. 2019. Cell Mol Gastroenterol Hepatol. 7:623. PubMed
  64. Kenichi Shimada et al. 2018. Immunity. 49(5):873-885 . PubMed
  65. Kobayashi T, et al. 2019. Cell. 176:982. PubMed
  66. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  67. Súarez-López L, et al. 2021. iScience. 24:103406. PubMed
  68. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  69. Hirano KI, et al. 2021. eLife. 0.416666666666667. PubMed
  70. Yuan Q, et al. 2021. Cell Reports. 34(5):108724. PubMed
  71. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  72. Amano C, et al. 2015. PLoS One. 10: 0137207. PubMed
  73. Sun P, et al. 2015. J Hepatol. . PubMed
  74. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  75. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  76. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  77. Tan X, et al. 2021. Front Oncol. 11:768222. PubMed
  78. Biswas S, et al. 2021. Nature. 591:464. PubMed
  79. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  80. Neubert K, et al. 2014. J Immunol. 192:5830. PubMed
  81. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  82. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  83. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  84. Nguyen SL, et al. 2021. Sci Rep. 11:4217. PubMed
  85. Cai B, et al. 2021. Mol Cancer. 20:165. PubMed
  86. Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
  87. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  88. Galle E, et al. 2022. Genome Biol. 23:207. PubMed
  89. Jiao H, et al. 2021. Cell. 184(11):2896-2910.e13. PubMed
  90. Lu S, et al. 2020. JCI Insight. 5:00. PubMed
  91. Koh EH, et al. 2018. Diabetes. 67(12). PubMed
  92. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  93. Anastasiou M, et al. 2021. JCI Insight. 6:. PubMed
  94. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  95. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  96. Plein A, et al. 2018. Nature. 562:223. PubMed
  97. Jeong SJ, et al. 2021. Autophagy. 17:3740. PubMed
  98. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  99. Bunn P, et al. 2014. J Immunol. 192:3709. PubMed
  100. Nishi C, et al. 2014. Mol Cell Biol. 34:1512. PubMed
  101. Fulham MA, et al. 2019. Am J Physiol Cell Physiol. 317:C687. PubMed
  102. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  103. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  104. Xu G, et al. 2022. Cell Death Dis. 13:888. PubMed
  105. Raineri D, et al. 2021. Biomedicines. 10:. PubMed
  106. Park D, et al. 2020. Cancer Res. 80:4172. PubMed
  107. Bretscher P, et al. 2015. EMBO Mol Med. 7:593. PubMed
  108. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  109. Qi T, et al. 2020. Cell Rep. 33:108452. PubMed
  110. Bogie JF, et al. 2020. Ther Adv Chronic Dis. 11:2040622320947378. PubMed
  111. Nayak RR, et al. 2021. Cell Host Microbe. 29(3):362-377.e11. PubMed
  112. Zhang F, et al. 2020. EMBO Mol Med. e12034:12. PubMed
  113. Yue X, et al. 2019. Nat Commun. 10:2011. PubMed
  114. Pereira JA, et al. 2020. Hum Mol Genet. 29:1253. PubMed
  115. Lu CY, et al. 2020. J Neurosci. 40:9602. PubMed
  116. Okamura T, et al. 2021. Front Immunol. 12:669629. PubMed
  117. Qian SJ, et al. 2021. Front Immunol. 12:711337. PubMed
  118. Wang J, et al. 2021. Nat Commun. 12:6198. PubMed
  119. Fennell LM, et al. 2020. EMBO J. 39:e103303. PubMed
  120. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  121. Li W, et al. 2021. Front Pharmacol. 12:697483. PubMed
  122. Yu Y, et al. 2022. Nat Commun. 13:6857. PubMed
  123. Xu Z, et al. 2020. Cancer Immunol Res. 1354:8. PubMed
  124. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  125. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  126. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  127. Lu S, et al. 2020. Arterioscler Thromb Vasc Biol. 40:394. PubMed
  128. Sun L, et al. 2015. J Immunol. 194:4891. PubMed
  129. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  130. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  131. Wei W, et al. 2022. mSystems. 7:e0046922. PubMed
  132. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  133. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  134. Xu M, et al. 2022. Genes Dis. 9:429. PubMed
  135. Sharma A, et al. 2020. Cell. 183(2):377-394.e21. PubMed
  136. Liu Z, et al. 2021. Immunity. 54(2):247-258.e7. PubMed
  137. Chung L et al. 2018. Cell host & microbe. 23(2):203-214 . PubMed
  138. Sasaki T, et al. 2020. Cell Reports. 28(1):202-217.e7.. PubMed
  139. Deczkowska A, et al. 2017. Nat Commun. 8:717. PubMed
  140. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  141. Carbone C, et al. 2021. J Immunother Cancer. 9:. PubMed
  142. Dagher T, et al. 2021. J Exp Med. 218:. PubMed
  143. Anger-Góra N, et al. 2021. Oncol Lett. 22:582. PubMed
  144. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  145. Stowe CL, et al. 2019. eLife. 0.333333333333333. PubMed
  146. Chatterjee D, et al. 2021. Cell Reports. 35(2):108996. PubMed
  147. Grauel AL, et al. 2020. Nat Commun. 4.84375. PubMed
  148. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  149. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  150. Lin W, et al. 2019. EBioMedicine. 49:133. PubMed
  151. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  152. Brown SM et al. 2017. Endocrinology. 158(10):3592-3604 . PubMed
  153. López MJ, et al. 2018. Invest Ophthalmol Vis Sci. 59:5671. PubMed
  154. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  155. Wu S, et al. 2022. BMC Immunol. 23:17. PubMed
  156. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  157. Zhao D, et al. 2020. Cancer Discov. 10:1374. PubMed
  158. Cruz-Herranz A, et al. 2021. JCI Insight. 6: . PubMed
  159. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  160. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  161. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  162. Bhattacharya A, et al. 2018. Neuropsychopharmacology. 43:2586. PubMed
  163. Carestia A, et al. 2019. Cell Rep. 28:896. PubMed
  164. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  165. Chruewkamlow N, et al. 2021. Stem Cell Res Ther. 12:520. PubMed
  166. Vachon L, et al. 2022. Theranostics. 12:1440. PubMed
  167. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  168. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  169. Ni C, et al. 2021. Infect Immun. 89:. PubMed
  170. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  171. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  172. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  173. Sharif O, et al. 2013. J Immunol. 190:5640. PubMed
  174. Dulken BW, et al. 2019. Nature. 571:205. PubMed
  175. Muri J, et al. 2020. eLife. 9:e53627.. PubMed
  176. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  177. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  178. Hightower RM, et al. 2019. Mol Ther. 28:189. PubMed
  179. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  180. Bitschar K, et al. 2019. Nat Commun. 10:2730. PubMed
  181. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  182. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  183. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  184. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  185. Raoof R, et al. 2021. J Neurosci. 41:8249. PubMed
  186. Guo D, et al. 2022. Bone Res. 10:45. PubMed
  187. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  188. Bennett FC, et al. 2018. Neuron. 98:1170. PubMed
  189. Yang X, et al. 2018. Sci Rep. 8:188. PubMed
  190. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  191. Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
  192. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  193. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  194. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  195. Unsinger J, et al. 2021. J Leukoc Biol. 109:697. PubMed
  196. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  197. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  198. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  199. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  200. Liao Y, et al. 2020. Theranostics. 7.113888889. PubMed
  201. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  202. Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
  203. Muchenditsi A, et al. 2017. Am J Physiol Gastrointest Liver Physiol. 313:G39. PubMed
  204. Tothova Z et al. 2017. Cell stem cell. 21(4):547-555 . PubMed
  205. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  206. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  207. Xu JL, et al. 2022. Front Pharmacol. 13:911663. PubMed
  208. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  209. Hakim R, et al. 2021. J Neurosci. 41:8441. PubMed
  210. Gu H, et al. 2021. Elife. 10:. PubMed
  211. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  212. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  213. Chen J, et al. 2017. Sci Rep. 10.1038/s41598-017-00654-2. PubMed
  214. Danzer H, et al. 2020. Elife. 9:00. PubMed
  215. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  216. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  217. Molgora M, et al. 2020. Cell. 182:886. PubMed
  218. Starr T, et al. 2018. PLoS One. 13:e0193601. PubMed
  219. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  220. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  221. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  222. Jaitin DA et al. 2016. Cell. 167(7):1883-1896 . PubMed
  223. Zhang J, et al. 2018. Oncoimmunology. 7:e1461301. PubMed
  224. Werner A, et al. 2021. iScience. 24:103076. PubMed
  225. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  226. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  227. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  228. Baptista M, et al. 2016. Nat Commun. 7:12175. PubMed
  229. Guey B, et al. 2014. Proc Natl Acad Sci U S A. 111:17254. PubMed
  230. Ramanan D, et al. 2020. Cell. 181(6):1276-1290. PubMed
  231. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  232. Bohlen CJ et al. 2017. Neuron. 94(4):759-773 . PubMed
  233. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  234. Ishihara J, et al. 2018. Nat Commun. 9:2163. PubMed
  235. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  236. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  237. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  238. Sakamoto K, et al. 2022. STAR Protoc. 3:101052. PubMed
  239. Tummala G, et al. 2021. Invest Ophthalmol Vis Sci. 62:41. PubMed
  240. Maller O, et al. 2020. Nat Mater. 20:548. PubMed
  241. Lee J, et al. 2015. Nat Commun. 6: 8499. PubMed
  242. Sen D, et al. 2016. PLoS One. 11:e0165064. PubMed
  243. Liddelow S, et al. 2017. Nature. 541:481-487. PubMed
  244. Xu Z, et al. 2020. Cell Rep. 32:108041. PubMed
  245. Ang QY, et al. 2020. Cell. 181(6):1263-1275.e16. PubMed
  246. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  247. Koyama M et al. 2019. Immunity. 51(5):885-898 . PubMed
  248. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  249. Tripathi A, et al. 2021. Mol Psychiatry. 26:3043. PubMed
  250. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  251. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  252. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  253. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  254. Kapralov AA, et al. 2020. Nat Chem Biol. 278:16. PubMed
  255. Zheng H, et al. 2021. Frontiers in Immunology. 12:645100. PubMed
  256. Han J, et al. 2015. Cancer Res . 75: 5273 - 5282. PubMed
  257. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  258. Strattan E, et al. 2020. Frontiers in Immunology. 2.131944444. PubMed
  259. Ribechini E, et al. 2017. Blood Adv. 0.699305556. PubMed
  260. Tan DQ, et al. 2019. Cell Rep. 26:2316. PubMed
  261. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  262. Aurélien Trompette et al. 2018. Immunity. 48(5):992-1005 . PubMed
  263. Chithanathan K, et al. 2022. Biology (Basel). 11:. PubMed
  264. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  265. Erens C, et al. 2022. Biomedicines. 10:. PubMed
  266. Yang F, et al. 2021. Nat Commun. 12:3424. PubMed
RRID
AB_893232 (BioLegend Cat. No. 101227)
AB_893232 (BioLegend Cat. No. 101228)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
PE/Fire™ 744 anti-mouse/human CD11b M1/70 FC
Spark PLUS UV395™ anti-mouse/human CD11b M1/70 FC
Spark Red™ 718 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
Go To Top Version: 2    Revision Date: 11.19.2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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