APC/Cyanine7 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
M1slash70_APCCy7_021808
C57BL/6 mouse bone marrow stained with M1/70 APC/Cyanine7
  • M1slash70_APCCy7_021808
    C57BL/6 mouse bone marrow stained with M1/70 APC/Cyanine7
Compare all formats See APC/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability
101225 25 µg $94.00
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101226 100 µg $216.00
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Technical data sheet

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Casellas Roman HL, et al. 2020. Leuk Res. 94:106372. PubMed
  2. Yokozeki Y, et al. 2021. Biomed Res Int. 2021:7988320. PubMed
  3. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  4. Fu A, et al. 2022. Cell. 185:1356. PubMed
  5. Dolfi B, et al. 2022. Cell Rep. 39:110949. PubMed
  6. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  7. McAlpine CS, et al. 2022. J Exp Med. 219: . PubMed
  8. Balood M, et al. 2022. Nature. 611:405. PubMed
  9. Hill AA, et al. 2023. JCI Insight. 8: . PubMed
  10. Guo J, et al. 2023. Cell Rep Med. 4:100881. PubMed
  11. Fan R, et al. 2023. J Immunother Cancer. 11: . PubMed
  12. Lombard-Vadnais F, et al. 2023. iScience. 26:105852. PubMed
  13. Reticker-Flynn NE, et al. 2022. Cell. 185:1924. PubMed
  14. Brown A, et al. 2012. Arterioscler Thromb Vasc Biol. 32:2122. PubMed
  15. Dixit N, et al. 2012. J Immunol. 189:5954. PubMed
  16. Wangdi T, et al. 2014. PLoS Pathog. 10:1004306. PubMed
  17. Chung Y, et al. 2014. J Vis Exp. 89: 51660. PubMed
  18. Daemen S, et al. 2021. Cell Reports. 34(2):108626. PubMed
  19. Sweet R, et al. 2017. J Immunol. 10.4049/jimmunol.1600861. PubMed
  20. Filipello F et al. 2018. Immunity. 48(5):979-991 . PubMed
  21. Mathur R, et al. 2019. Mucosal Immunol. 12:612. PubMed
  22. Miragaia RJ, et al. 2019. Immunity. 50:493. PubMed
  23. Murray C, et al. 2022. Int J Mol Sci. 23:. PubMed
  24. Alghamri MS, et al. 2022. ACS Nano. 16:8729. PubMed
  25. Diamantopoulou Z, et al. 2022. Nature. 607:156. PubMed
  26. Chang CY, et al. 2022. Sci Adv. 8:eabq0615. PubMed
  27. Shi H, et al. 2022. Nutrients. 14:. PubMed
  28. Swan SL, et al. 2023. Front Immunol. 14:1085547. PubMed
  29. Le DT, et al. 2023. iScience. 26:106059. PubMed
  30. Gu J, et al. 2023. J Cell Biochem. 124:557. PubMed
  31. Henn RE, et al. 2023. iScience. 26:106164. PubMed
  32. Larson-Casey JL, et al. 2023. JCI Insight. 8:. PubMed
  33. Xiao Y, et al. 2023. EMBO J. 42:e111762. PubMed
  34. Fukuzaki Y, et al. 2023. iScience. 26:106340. PubMed
  35. Wang HY, et al. 2023. Exp Hematol Oncol. 12:35. PubMed
  36. Palakurthi B, et al. 2023. Nat Commun. 14:2109. PubMed
  37. Okano F, et al. 2023. Cancer Res Commun. 3:640. PubMed
  38. Choconta JL, et al. 2023. Immun Ageing. 20:22. PubMed
  39. Ishida K, et al. 2023. Front Immunol. 14:1111729. PubMed
  40. He Y, et al. 2023. Biomolecules. 13:. PubMed
  41. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  42. Lan Y, et al. 2023. iScience. 26:106817. PubMed
  43. Yang N, et al. 2022. NPJ Vaccines. 7:120. PubMed
  44. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  45. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  46. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  47. Nguyen NDNT, et al. 2020. NPJ Vaccines. 5:7. PubMed
  48. Larson-Casey JL, et al. 2021. FASEB J. 35:e21675. PubMed
  49. Savio LEB, et al. 2020. J Cell Sci. 133:jcs237560. PubMed
  50. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  51. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  52. Zhou J, et al. 2019. Immunity. 50:403. PubMed
  53. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
  54. Cho SM et al. 2018. Journal of neurochemistry. 148(5):625-638 . PubMed
  55. Sakamoto T, et al. 2021. Commun Biol. 4:1165. PubMed
  56. Chen S, et al. 2022. Cancer Discov. :. PubMed
  57. Gattas MJ, et al. 2021. International Journal of Molecular Sciences. 22(10):. PubMed
  58. Yilmaz B, et al. 2021. Cell Host Microbe. 29(4):650-663.e9. PubMed
  59. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  60. Giambra V et al. 2018. Cell stem cell. 23(5):714-726 . PubMed
  61. Lino AC et al. 2018. Immunity. 49(1):120-133 . PubMed
  62. Zhang K, et al. 2018. PLoS Pathog. 14:e1006925. PubMed
  63. Delás MJ, et al. 2019. Cell Rep. 27:719. PubMed
  64. Kashyap AS, et al. 2019. Cell Rep. 28:3367. PubMed
  65. Yang M, et al. 2020. Cell Prolif. 53:e12784. PubMed
  66. Achmus L, et al. 2020. Front Neurol. 11:577971. PubMed
  67. Nagatake T, et al. 2022. Mucosal Immunol. 15:289. PubMed
  68. Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
  69. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  70. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  71. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  72. Clement M, et al. 2016. PLoS Pathog. 12:e1006050. PubMed
  73. Billroth-MacLurg, AC, et al. 2016. J Immunol. 197:2208-2218. PubMed
  74. Eastman A, et al. 2016. J Immunol . 194: 5999-6010. PubMed
  75. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  76. Spees A, et al. 2013. MBio. 2:430. PubMed
  77. Harel M, et al. 2020. Cell. 179(1):236-250.e18.. PubMed
  78. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  79. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  80. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  81. Kleinholz CL, et al. 2021. Sci Rep. 11:15071. PubMed
  82. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  83. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  84. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  85. Yang F, et al. 2020. Cancer Res. 80:3677. PubMed
  86. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  87. Getts D, et al. 2014. Sci Transl Med. 15:219. PubMed
  88. Tanaka Y, et al. 2015. PLoS One. 10: 0138621. PubMed
  89. Palamides P, et al. 2016. Dis Model Mech. 9: 985 - 997. PubMed
  90. Wang H, et al. 2019. Immunotherapy. 11:101. PubMed
  91. Davis FM, et al. 2019. Arterioscler Thromb Vasc Biol. 39:2353. PubMed
  92. Di Gioia M, et al. 2020. Nat Immunol. 21:42. PubMed
  93. Bhattacherjee A, et al. 2021. Mol Neurodegener. 16:19. PubMed
  94. Wang C, et al. 2021. Cell Rep. 37:110021. PubMed
  95. Stahlhut M, et al. 2021. Sci Rep. 11:5294. PubMed
  96. Gordon RA, et al. 2020. PLoS One. 15:e0226396. PubMed
  97. Diao N, et al. 2016. Sci Rep. 6:34672. PubMed
  98. Krueger K, et al. 2014. Stem Cell Reports. 9:1147. PubMed
  99. Saika A, et al. 2020. FASEB Bioadv. 2:59. PubMed
  100. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  101. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  102. Mariani SA, et al. 2019. Immunity. 50:1439. PubMed
  103. Goggi JL, et al. 2020. Mol Imaging Biol. 22:1392. PubMed
  104. Zhang X, et al. 2022. Theranostics. 12:1621. PubMed
  105. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  106. Wu X, et al. 2021. Elife. 10:. PubMed
  107. Wang B, et al. 2022. Nat Commun. 13:3821. PubMed
  108. Jiang N, et al. 2022. Nat Commun. 13:1511. PubMed
  109. Glass A, et al. 2013. J Immunol. 190:4830. PubMed
  110. Kurkewich J, et al. 2016. PLoS One. 11: 0161468. PubMed
  111. Jeljeli M, et al. 2020. Cell Rep. 33:108325. PubMed
  112. Hagan AS, et al. 2020. Development. 147:00:00. PubMed
  113. Wei SC, et al. 2020. Cancer Discov. . PubMed
  114. Dos Santos Dias L, et al. 2021. PLoS Pathog. e1009324:17. PubMed
  115. Kunimoto H, et al. 2018. Cancer Cell. 33:44. PubMed
  116. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  117. Parlet CP, et al. 2019. Cell Rep. 27:187. PubMed
  118. Zhang S, et al. 2019. Cell Metab. 29:443. PubMed
  119. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  120. García-Bonilla M, et al. 2020. Stem Cell Res Ther. 11:121. PubMed
  121. Yang L, et al. 2021. Cell Death Differ. 28:2616. PubMed
  122. McAlpine CS, et al. 2021. Nature. 595:701. PubMed
  123. Naler LB, et al. 2022. Commun Biol. 5:102. PubMed
  124. Kornstädt L, et al. 2021. Front Immunol. 11:607048. PubMed
  125. Kirschbaum K, et al. 2016. Proc Natl Acad Sci U S A. 113: 13227 - 13232. PubMed
  126. Ano Y, et al. 2017. J Biol Chem. 292:3720. PubMed
  127. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  128. Kleppe M et al. 2018. Cancer cell. 33(1):29-43 . PubMed
  129. Kobayashi M, et al. 2020. Bio Protoc. 10:e3601. PubMed
  130. Geng S, et al. 2021. JCI Insight. 6:. PubMed
  131. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  132. Pan Y, et al. 2022. J Clin Invest. 132:. PubMed
  133. Zhu Y, et al. 2022. Clin Transl Med. 12:e887. PubMed
  134. Feng S, et al. 2022. Front Immunol. 13:990522. PubMed
  135. Hutter K, et al. 2020. FEBS J. . PubMed
  136. Zhao J, et al. 2018. Stem Cell Reports. 10:180. PubMed
  137. Mamedov MR, et al. 2018. Immunity. 48:350. PubMed
  138. Codina A, et al. 2019. Cell Syst. 8:136. PubMed
  139. Hulsmans M et al. 2017. Cell. 169(3):510-522 . PubMed
  140. Yu X, et al. 2020. Nat Commun. 0.641666667. PubMed
  141. Vicencio JM, et al. 2022. Cell Death Dis. 13:274. PubMed
  142. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  143. Pradhan K, et al. 2021. Front Immunol. 12:778830. PubMed
  144. Panea C, et al. 2021. Commun Biol. 4:913. PubMed
  145. Witkowski MT, et al. 2020. Cancer Cell. 37:867. PubMed
  146. Hu Y, et al. 2021. Bioact Mater. 2905:6. PubMed
  147. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  148. McFarland AP, et al. 2021. Immunity. 54(6):1320-1337.e4. PubMed
  149. Kenswil KJG, et al. 2021. Cell Stem Cell. 28(4):653-670.e11. PubMed
  150. Zhang C, et al. 2020. Cell Rep. 32:108206. PubMed
  151. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  152. Niknam S, et al. 2018. Clin Cancer Res. 24:5735. PubMed
  153. Pfefferlé M, et al. 2021. Front Immunol. 12:680855. PubMed
  154. Ma S, et al. 2022. Cell Rep. 38:110520. PubMed
  155. Guldner IH, et al. 2020. Cell. 183(5):1234-1248.e25. PubMed
  156. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  157. Martínez‐López M et al. 2019. Immunity. 50(2):446-461 . PubMed
  158. Casulli J, et al. 2019. Nat Commun. 10:2121. PubMed
  159. Xiong X et al. 2019. Mol Cell. 75(3):644-660 . PubMed
  160. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  161. Pietronigro E, et al. 2019. Sci Rep. 9:12055. PubMed
  162. Yang S, et al. 2022. J Exp Med. 219:. PubMed
  163. Cheresh P, et al. 2020. Int J Mol Sci. 21:. PubMed
  164. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  165. Larson-Casey JL, et al. 2021. J Biol Chem. :100810. PubMed
  166. San Gil R, et al. 2021. Cells. 10: . PubMed
  167. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  168. Yi W, et al. 2021. Cell Reports. 34(13):108922. PubMed
  169. Murakami K, et al. 2021. Cell Reports. 34(1):108579. PubMed
  170. LM S, et al. 2016. Cell Rep. 16(12): 3286-96. PubMed
  171. Lammers K, et al. 2015. PLoS One. 10: 0138338. PubMed
  172. Ermert D, et al. 2016. PLoS Pathog. 11: 1005043. PubMed
  173. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  174. Crane A, et al. 2018. Alzheimers Dement. 14:243. PubMed
  175. Chen Z, et al. 2019. J Exp Med. 216:152. PubMed
  176. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  177. Landon J Edgar et al. 2018. Cell chemical biology. 26(1):131-136 . PubMed
  178. Liu S, et al. 2018. Front Immunol. 29:208. PubMed
  179. Daemen S, et al. 2021. STAR Protoc. 2:100511. PubMed
  180. Shibad V, et al. 2021. Front Immunol. 12:722451. PubMed
  181. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  182. Robles-Oteiza C, et al. 2021. Dis Model Mech. 14:. PubMed
  183. Gómez LA, et al. 2020. Front Microbiol. 11:1586. PubMed
  184. Xu X, et al. 2022. EMBO Rep. 23:e53509. PubMed
  185. Yabas M, et al. 2016. PLoS One. 11: 0146774. PubMed
  186. Wu X, et al. 2016. Sci Rep. 6:18685. PubMed
  187. Savio LEB, et al. 2020. J Cell Sci. 133:00:00. PubMed
  188. Li CJ, et al. 2018. J Clin Invest. 128:5251. PubMed
  189. Goldstein JM et al. 2019. Cell reports. 27(4):1254-1264 . PubMed
  190. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  191. Carestia A, et al. 2019. Cell Rep. 28:896. PubMed
  192. Zhang CR, et al. 2022. Blood Cancer Discov. 3:220. PubMed
  193. Anderson-Baucum E, et al. 2021. Cell Metab. 33:1883. PubMed
  194. Mendelsohn AC, et al. 2020. Am J Physiol Cell Physiol. 319:C997. PubMed
  195. King R, et al. 2021. Sci Adv. 7:eabj5293. PubMed
  196. Murdock BJ, et al. 2021. JCI Insight. 6:. PubMed
  197. Taya M, et al. 2020. Endocr Relat Cancer. 27:261. PubMed
  198. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  199. Larson-Casey JL, et al. 2020. PLoS One. 15:e0241323. PubMed
  200. Kim M, et al. 2018. Immunity. 49:151. PubMed
  201. Nowak W, et al. 2020. EBioMedicine. 50:290-305.. PubMed
  202. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  203. Qiao S, et al. 2019. J Neuroinflammation. 16:4. PubMed
  204. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  205. Sia J, et al. 2017. PLoS Pathog.. 10.1371/journal.ppat.1006530. PubMed
  206. Bhatt D, et al. 2021. J Exp Med. 218:. PubMed
  207. Karolin A, et al. 2022. Front Pharmacol. 12:789080. PubMed
  208. Gao Z, et al. 2022. J Inflamm Res. 15:3337. PubMed
  209. Jing Y, et al. 2021. Front Immunol. 12:651860. PubMed
  210. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  211. Celik H, et al. 2018. Cancer Cell. 34:741. PubMed
  212. Yin S et al. 2019. Cancer cell. 35(2):283-296 . PubMed
  213. Zhao Y, et al. 2020. Immunity. 51(6):1059-1073.e9.. PubMed
  214. Soncin I, et al. 2018. Nat Commun. 9:582. PubMed
  215. Tulyeu J, et al. 2021. Curr Protoc. 1:e283. PubMed
  216. Zhang W, et al. 2021. Front Immunol. 12:768435. PubMed
  217. Wang Z, et al. 2020. J Cell Mol Med. . PubMed
  218. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  219. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  220. Flores AM, et al. 2020. Nat Nanotechnol. 0.731944444. PubMed
  221. McKenzie MD, et al. 2019. Cell Stem Cell. 25:258. PubMed
  222. Pradhan K, et al. 2021. J Immunol. 206:2980. PubMed
  223. Smith KJ, et al. 2022. PLoS Biol. 20:e3001554. PubMed
  224. Zhang L, et al. 2021. Front Mol Biosci. 8:647647. PubMed
  225. Liu Q, et al. 2021. Adv Mater. 33:e2102852. PubMed
  226. Lin R, et al. 2022. Cell Death Dis. 13:345. PubMed
  227. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  228. Hoyer FF, et al. 2020. Immunity. 51(5):899-914.e7.. PubMed
  229. Fite BZ, et al. 2021. Sci Rep. 11:927. PubMed
  230. Schmit T, et al. 2022. Cell Rep. 38:110456. PubMed
  231. Liu X, et al. 2021. Adv Sci (Weinh). 8:e2100233. PubMed
  232. Chavkin NW, et al. 2021. J Am Heart Assoc. 10:e019904. PubMed
  233. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  234. Siolas D, et al. 2021. Cell Reports. 36:109578. PubMed
  235. Aryal B, et al. 2016. Nat Commun. 7:12313. PubMed
  236. Lee MC, et al. 2017. J Immunol. 198:3565. PubMed
  237. Säwen P et al. 2018. eLife. 7 pii: e41258. PubMed
  238. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  239. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  240. Park HJ, et al. 2021. Int J Mol Sci. 22:. PubMed
  241. Wang X, et al. 2021. Sci Transl Med. 13:. PubMed
  242. Lau A, et al. 2022. Sci Adv. 8:eabm0142. PubMed
  243. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  244. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  245. Larson–Casey JL, et al. 2019. J Clin Invest. 129:4962. PubMed
  246. Patterson DG, et al. 2021. J Immunol. 207:1798. PubMed
  247. Lippeveld M, et al. 2020. Cytometry A. 97:308. PubMed
  248. Avgustinova A, et al. 2021. Cell Stem Cell. . PubMed
  249. Cortez MA, et al. 2020. Nat Commun. 3.819444444. PubMed
  250. C Khouili S, et al. 2020. Cell Rep. 33:108468. PubMed
  251. Geng S, et al. 2016. Nat Commun. 7:13436. PubMed
  252. Denk F, et al. 2016. Cell Rep. 15: 1771-1781. PubMed
  253. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  254. Ge Y, et al. 2020. Mucosal Immunol. 13:34. PubMed
  255. Cabal-Hierro L, et al. 2020. Nat Commun. 11:1406. PubMed
  256. Syed I et al. 2018. Cell metabolism. 27(2):419-427 . PubMed
RRID
AB_830641 (BioLegend Cat. No. 101225)
AB_830641 (BioLegend Cat. No. 101226)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
UniProt
View information about CD11b on UniProt.org

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
PE/Fire™ 744 anti-mouse/human CD11b M1/70 FC
Spark PLUS UV395™ anti-mouse/human CD11b M1/70 FC
Spark Red™ 718 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
Go To Top Version: 1    Revision Date: 11/30/2012

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Login/Register
Forgot your password? Reset Password
Request an Account