Loading...

PE/Cyanine7 anti-mouse CD11c Antibody

Pricing & Availability
Clone
N418 (See other available formats)
Regulatory Status
RUO
Other Names
αX integrin, integrin αX chain, CR4, p150, ITGAX
Isotype
Armenian Hamster IgG
Ave. Rating
Submit a Review
Product Citations
publications
N418_PECyanine7_CD11c_Antibody_1_111924
C57BL/6 mouse splenocytes stained with APC anti-mouse I-A/I-E (clone M5/114.15.2) and PE/Cyanine7 N418 (left) or PE/Cyanine7 Armenian hamster IgG isotype control (right)
  • N418_PECyanine7_CD11c_Antibody_1_111924
    C57BL/6 mouse splenocytes stained with APC anti-mouse I-A/I-E (clone M5/114.15.2) and PE/Cyanine7 N418 (left) or PE/Cyanine7 Armenian hamster IgG isotype control (right)
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
117317 25 µg 94 CHF
Check Availability


Need larger quantities of this item?
Request Bulk Quote
117318 100 µg 231 CHF
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse spleen dendritic cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for other applications.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9 (Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.

Additional Product Notes

View more applications data for this product in our Scientific Poster Library.

Application References

(PubMed link indicates BioLegend citation)
  1. Granucci F, et al. 1997. J. Immunol. 159:1794.
  2. Stokes RW, et al. 1998. J. Immunol. 160:5514.
  3. Metlay JP, et al. 1990. J. Exp. Med. 171:1753. (IHC, IP)
  4. Ma XT, et al. 2006. Cancer Research 66:1169.
  5. Chin RK, et al. 2006. J. Immunol. 177:290. (IF)
  6. Cervantes-Barragan L, et al. 2007. Blood 109:1131. (FC) PubMed
  7. Turnquist HR, et al. 2007. J. Immunol. 178:7018. (FC) PubMed
  8. Benson MJ, et al. 2007. J. Exp. Med. doi:10.1084/jem.20070719. (FC) PubMed
  9. You Y, et al. 2009. J. Immunol. 182:7343. (IF) PubMed
  10. Roland CL, et al. 2009. Mol. Cancer Res. 8:1761. (IHC, FC) PubMed
  11. Wikstrom M, et al.2006. J. Immunol. 177:913. PubMed
  12. Pericolini E, et al. 2008. J. Leukocyte Biol. 83:1286. PubMed
  13. Randall LM, et al. 2008. Infect. Immun.76:3312. PubMed
  14. Fahlen-Yrild L, et al. 2009. J. Immunol. 183:5032. PubMed
  15. Osterholzer JJ, et al. 2009. J. Immunol. 183:8044. PubMed
  16. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed
  17. Eisenach PA, et al. 2010. J Cell Sci. 123:4182. PubMed
  18. Leppin K, et al. 2014. Invest. Ophthalmol. Vis. Sci. 55:3603. PubMed
  19. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  20. Gibbins JD, et al. 2014. Blood. 124:2953. PubMed
  21. White CE, et al. 2015. J Immunol. 194:697. PubMed
  22. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  23. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  24. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Jiang Z, et al. 2021. J Clin Invest. 131: . PubMed
  2. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  3. Friess MC, et al. 2022. Cell Rep. 38:110334. PubMed
  4. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  5. Furrer R, et al. 2021. Sci Adv. 7:eabi4852. PubMed
  6. Pohlmeier L, et al. 2021. Allergy. 76:2030. PubMed
  7. Russler-Germain EV, et al. 2021. Immunity. 54:2547. PubMed
  8. Aimaitijiang A, et al. 2022. Genes Cells. 27:25. PubMed
  9. Osokine I, et al. 2022. Cell Rep. 38:110329. PubMed
  10. Cautivo KM, et al. 2022. Immunity. 55:254. PubMed
  11. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  12. Wang S, et al. 2022. Sci Adv. 8:eabn3883. PubMed
  13. Mirchandani AS, et al. 2022. Nat Immunol. 23:927. PubMed
  14. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  15. He Y, et al. 2022. Front Immunol. 13:986202. PubMed
  16. Kraemer AN, et al. 2022. Front Immunol. 13:933191. PubMed
  17. Hill AA, et al. 2023. JCI Insight. 8: . PubMed
  18. Tatsumi N, et al. 2022. STAR Protoc. 3:101845. PubMed
  19. García-García A, et al. 2023. Bioact Mater. 24:174. PubMed
  20. Cousin N, et al. 2022. Cells. 12: . PubMed
  21. Sieow JL, et al. 2023. Int J Mol Sci. 24: . PubMed
  22. Lombard-Vadnais F, et al. 2023. iScience. 26:105852. PubMed
  23. Gonçalves R, et al. 2023. iScience. 26:105972. PubMed
  24. Wei J, et al. 2022. Cancer Prev Res (Phila). 15:285. PubMed
  25. Hailemichael Y, et al. 2022. Cancer Cell. 40:509. PubMed
  26. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  27. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  28. Komuczki J, et al. 2019. Immunity. 50:1289. PubMed
  29. Wang X, et al. 2019. Cell Res. 29:787. PubMed
  30. Kimura S, et al. 2020. Nat Commun. 0.620833333. PubMed
  31. Al–Rashed F, et al. 2020. Sci Rep. 10:16802. PubMed
  32. Morris CR, et al. 2022. Mucosal Immunol. 15:977. PubMed
  33. Kedmi R, et al. 2022. Nature. 610:737. PubMed
  34. Zimmerman SM, et al. 2022. Oncogene. 41:4983. PubMed
  35. Lutz MB, et al. 2022. Eur J Immunol. . PubMed
  36. Jia DJ, et al. 2022. Gut Microbes. 14:2145843. PubMed
  37. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  38. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  39. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  40. Xu H, et al. 2023. Elife. 12:. PubMed
  41. Matsuzawa M, et al. 2023. Nat Commun. 14:1417. PubMed
  42. Palakurthi B, et al. 2023. Nat Commun. 14:2109. PubMed
  43. Shen Z, et al. 2023. iScience. 26:106572. PubMed
  44. He Y, et al. 2023. Biomolecules. 13:. PubMed
  45. Zeng S, et al. 2023. Front Oncol. 13:1171926. PubMed
  46. van Vloten JP, et al. 2022. J Immunother Cancer. 10:. PubMed
  47. Ferrere G, et al. 2021. JCI Insight. 6:. PubMed
  48. Jong RM, et al. 2022. J Immunol. 208:407. PubMed
  49. Ercoli G, et al. 2021. Front Immunol. 11:611661. PubMed
  50. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
  51. Furuta Y, et al. 2017. PLoS One. 12(2):e0172509. PubMed
  52. Kolawole A, et al. 2015. J Virol. 90: 1499-1506. PubMed
  53. Kawano H, et al. 2016. Int Immunol. 28: 489 - 501. PubMed
  54. Shin J, et al. 2016. Sci Rep. 6:23426. PubMed
  55. Fu R, et al. 2020. Sci Rep. 10:1455. PubMed
  56. Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed
  57. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  58. Lyons J, et al. 2018. PLoS Biol. 16:e2002417. PubMed
  59. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  60. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  61. Boldison J, et al. 2020. Cell Mol Immunol. 17:843. PubMed
  62. Liang S, et al. 2022. Acta Pharm Sin B. 12:2494. PubMed
  63. Suzuki T, et al. 2014. J Dermatol Sci. 74:116. PubMed
  64. Clark K, et al. 2015. J Autoimmun. Available online 21 August 2015. PubMed
  65. Ndoja A, et al. 2020. Cell. 182(5):1156-1169.e12. PubMed
  66. Dong L, et al. 2021. Cancer Cell. . PubMed
  67. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  68. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  69. Thwe PM et al. 2017. Cell metabolism. 26(3):558-567 . PubMed
  70. Kurelac I, et al. 2019. Nat Commun. 10:903. PubMed
  71. Quatrini L, et al. 2018. Nat Immunol. 19:954. PubMed
  72. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  73. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  74. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  75. Yu X, et al. 2021. Nature. 594:560. PubMed
  76. Pack AD, et al. 2021. Cell Reports. 36:109586. PubMed
  77. Hearnden R, et al. 2021. STAR Protocols. 2(2):100422. PubMed
  78. Yousif AS, et al. 2020. Immunity. 54(2):235-246.e5. PubMed
  79. Ku M, et al. 2016. Mol Cancer Ther. 15: 1975 - 1987. PubMed
  80. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  81. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  82. Go DM, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:715. PubMed
  83. Papafragkos I, et al. 2022. Front Immunol. 13:889075. PubMed
  84. Morgado P, et al. 2014. Infect Immun . 82:4047. PubMed
  85. Ohtsuki T, et al. 2016. J Virol. 90: 300 - 307. PubMed
  86. Bazett M, Haston M 2016. Sci Rep. 6:19189. PubMed
  87. Rao S, et al. 2017. Cell. 168(3):503-516.e12. PubMed
  88. Si Y, et al. 2020. Sci Adv. 6:eaba0995. PubMed
  89. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  90. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  91. Jtte BB, et al. 2021. iScience. 24(8):102833. PubMed
  92. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  93. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  94. Khan IM, et al. 2021. Immunohorizons. 5:703. PubMed
  95. Zhang J, et al. 2022. Front Immunol. 13:931740. PubMed
  96. Zhang C, et al. 2021. Clin Transl Immunology. 10:e1310. PubMed
  97. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  98. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  99. Bagayoko S, et al. 2021. PLoS Pathog. 17:e1009927. PubMed
  100. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  101. Moreau GB, et al. 2020. Am J Trop Med Hyg. 103:1215. PubMed
  102. van Dierendonck XAMH, et al. 2020. Cell Reports. 30(6):1811-1822. PubMed
  103. Nguyen CM, et al. 2019. Diabetes. 68:1499. PubMed
  104. Britton GJ et al. 2019. Immunity. 50(1):212-224 . PubMed
  105. Lyons J, et al. 2018. Sci Signal. 11. PubMed
  106. Wu X, et al. 2021. Elife. 10:. PubMed
  107. Škrnjug I, et al. 2014. PLoS One. 9:110150. PubMed
  108. Lee M, et al. 2014. PLoS One. 9:112666. PubMed
  109. Syed A, et al. 2015. Infect Immun . 83: 3428-3437. PubMed
  110. Zhang Y, et al. 2015. PLoS Pathog. 11: e1005167. PubMed
  111. Ben-Shaanan T, et al. 2016. Nat Med. 10.1038/nm.4133. PubMed
  112. Koren N, et al. 2021. Cell Host Microbe. 29(2):197-209.e5. PubMed
  113. An J,et al. 2017. Sci Rep.. 10.1038/s41598-017-13629-0. PubMed
  114. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  115. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  116. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  117. Zeng J, et al. 2019. Cell Rep. 27:549. PubMed
  118. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  119. Crosse EI, et al. 2020. Cell Stem Cell. 27:822. PubMed
  120. Sellau J, et al. 2016. Sci Rep. 6:28058. PubMed
  121. Rosen D, et al. 2016. J Infect Dis. 213: 649 - 658. PubMed
  122. Kelsey E Sivick et al. 2018. Cell reports. 25(11):3074-3085 . PubMed
  123. Fatkhullina AR et al. 2018. Immunity. 49(5):943-957 . PubMed
  124. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  125. Pan Y, et al. 2022. J Clin Invest. 132:. PubMed
  126. Novkovic M, et al. 2016. PLoS Biol. 14: 1002515. PubMed
  127. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  128. Souza COS, et al. 2021. iScience. 24(6):102548. PubMed
  129. Connick K, et al. 2020. J Parasit Dis. 186:44. PubMed
  130. Johnson LA, et al. 2021. Life Sci Alliance. :4. PubMed
  131. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  132. Si Y, et al. 2018. J Control Release. 282:120. PubMed
  133. Baudoux T, et al. 2018. Sci Rep. 4.0375. PubMed
  134. Krollmann C, et al. 2022. STAR Protoc. 3:101309. PubMed
  135. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  136. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  137. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  138. Ercoli G, et al. 2022. Clin Transl Immunology. 11:e1366. PubMed
  139. Lewis EL, et al. 2021. Front Immunol. 12:741518. PubMed
  140. Panea C, et al. 2021. Commun Biol. 4:913. PubMed
  141. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  142. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  143. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  144. Vettorazzi S, et al. 2015. Nat Commun. 6: 7796. PubMed
  145. Christ A, et al. 2018. Cell. 172:162. PubMed
  146. Calcinotto A, et al. 2018. Nat Commun. 9:4832. PubMed
  147. Habib S, et al. 2018. Infect Immun. 86:e00019. PubMed
  148. Nikolos F, et al. 2022. Nat Commun. 13:1487. PubMed
  149. Colombo M, et al. 2022. iScience. 25:105042. PubMed
  150. Gibbins J, et al. 2014. Blood. 124:2953. PubMed
  151. Schaefer K, et al. 2014. PLoS One. 9:114824. PubMed
  152. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  153. Kim SH, et al. 2021. Cell Reports. 35(2):108995. PubMed
  154. Moon HG et al. 2018. Immunity. 49(2):275-287 . PubMed
  155. Hiebert P et al. 2018. Developmental cell. 46(2):145-161 . PubMed
  156. Tran NT, et al. 2020. STAR Protocols. 1(1):100028. PubMed
  157. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  158. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  159. Puigdelloses M, et al. 2021. J Immunother Cancer. 9:. PubMed
  160. Daneshmandi S, et al. 2021. Elife. 10:. PubMed
  161. Henrich IC, et al. 2021. Cancer Res. 81:2171. PubMed
  162. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  163. Reimer E, et al. 2020. J Cell Sci. 134:00:00. PubMed
  164. Cuenca M, et al. 2016. J Immunol. 196: 726 - 737. PubMed
  165. Hayashi K, et al. 2015. Int Immunol. 27: 435-445. PubMed
  166. Ermert D, et al. 2016. PLoS Pathog. 11: 1005043. PubMed
  167. Choi EW, et al. 2020. Sci Rep. 10:12001. PubMed
  168. Yang C, et al. 2019. Nanomedicine (Lond). 14:2423. PubMed
  169. Janela B, et al. 2019. Immunity. 50:1069. PubMed
  170. Taddio MF, et al. 2021. Mol Imaging Biol. 23:196. PubMed
  171. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  172. Yang X, et al. 2022. Front Immunol. 13:856230. PubMed
  173. Colliou N, et al. 2015. Toxins. 7: 3805 - 3817. PubMed
  174. Shepardson K, et al. 2016. MBio. 7: e00506-16. PubMed
  175. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  176. Lan H, et al. 2020. Int Immunol. 559:32. PubMed
  177. Ghorbani S, et al. 2022. Nat Commun. 13:2445. PubMed
  178. Clement CC, et al. 2021. Immunity. 54:721. PubMed
  179. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  180. Morikawa M, et al. 2016. PLoS One. 11:e0163607. PubMed
  181. Kim M, et al. 2018. Immunity. 49:151. PubMed
  182. Lu Y, et al. 2020. Immunity. 52:782. PubMed
  183. Dahlgren MW et al. 2019. Immunity. 50(3):707-722 . PubMed
  184. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  185. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  186. Zwick M, et al. 2019. Front Immunol. 10:222. PubMed
  187. Chan WY, et al. 2019. Infect Immun. 87:. PubMed
  188. Li E, et al. 2021. Front Immunol. 12:667177. PubMed
  189. He S, et al. 2021. Front Pharmacol. 12:743837. PubMed
  190. Wang L, et al. 2021. Sci Adv. 7:eabj4796. PubMed
  191. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  192. Hennion-Tscheltzoff O, et al. 2013. Blood. 121:4684. PubMed
  193. Škrnjug I, et al. 2014. PLoS One. 9:95728. PubMed
  194. Velázquez F, et al. 2016. J Immunol. 196: 1305 - 1316. PubMed
  195. Ghosh D, et al. 2016. J Immunol. 197: 1788 - 1800. PubMed
  196. Yasuda T, et al. 2016. PLoS One. 11:e0167952. PubMed
  197. Kumari P, et al. 2021. Cell Reports. 35(3):109012. PubMed
  198. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  199. Andersen TK, et al. 2019. NPJ Vaccines. 4:9. PubMed
  200. Lai SM et al. 2018. Cell reports. 25(11):3099-3109 . PubMed
  201. Urata S, et al. 2018. PLoS Pathog. 14:e1007172. PubMed
  202. Zhao Y, et al. 2020. Immunity. 51(6):1059-1073.e9.. PubMed
  203. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  204. Harb H, et al. 2020. Nat Immunol. 1359:21. PubMed
  205. Niven J, et al. 2019. Cell Rep. 28:21. PubMed
  206. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  207. Donlan AN, et al. 2021. JCI Insight. 6: . PubMed
  208. Okreglicka K, et al. 2021. J Exp Med. 218:. PubMed
  209. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  210. Di Pilato M, et al. 2021. Cell. 184(17):4512-4530.e22. PubMed
  211. Chung S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. L921:318. PubMed
  212. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  213. Porrello A, et al. 2018. Nat Commun. 9:1988. PubMed
  214. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  215. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  216. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  217. Stotesbury C, et al. 2020. Aging Cell. 19:e13170. PubMed
  218. Teng F, et al. 2021. Cell Rep. 37:110051. PubMed
  219. Ceglia V, et al. 2021. J Immunol. 207:2060. PubMed
  220. Bahmani B, et al. 2021. Nat Commun. 12:1999. PubMed
  221. Fite BZ, et al. 2021. Sci Rep. 11:927. PubMed
  222. Lee HN, et al. 2022. JCI Insight. 7:. PubMed
  223. Verma M, et al. 2021. J Exp Med. 218:. PubMed
  224. Kim J, et al. 2020. Adv Funct Mater. 30:. PubMed
  225. Lee GR, et al. 2021. JCI Insight. 6:. PubMed
  226. Van Nuffel E, et al. 2020. EMBO Rep. 21:e49237. PubMed
  227. Liu SS, et al. 2021. Immunity. :. PubMed
  228. Xu C, et al. 2021. Cell Reports. 35(11):109235. PubMed
  229. Hildreth AD, et al. 2020. STAR Protoc. 1:100113. PubMed
  230. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  231. Wan X, Thomas J, Unanue E 2016. J Exp Med. 213: 967 - 978. PubMed
  232. Yu H, et al. 2015. PLoS One. 10: 0143001. PubMed
  233. Jin J, et al. 2020. Cell Reports. 30(12):4124-4136. PubMed
  234. Schuh E, et al. 2017. J Immunol. 198:3081. PubMed
  235. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  236. Schäfer AL, et al. 2021. Front Immunol. 12:696810. PubMed
  237. Hsu HP, et al. 2021. J Biol Chem. 296:100419. PubMed
  238. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  239. Dietschmann A, et al. 2020. Eur J Immunol. 50:1044. PubMed
  240. Stack G, et al. 2015. PLoS Pathog. 11:1004641. PubMed
  241. Tran S, et al. 2020. Immunity. 53(3):627-640.e5. PubMed
  242. Goc J, et al. 2021. Cell. 184:5015. PubMed
  243. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  244. Albaghdadi AJH, et al. 2019. Sci Rep. 9:6528. PubMed
  245. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  246. Crowe J, et al. 2020. PLoS Pathog. 16:e1008391. PubMed
  247. Saleh R, et al. 2018. J Immunol. 201:2042. PubMed
  248. Doo DW, et al. 2020. Ther Adv Med Oncol. 12:1758835920913798. PubMed
  249. Wirasinha RC, et al. 2021. J Exp Med. 218: . PubMed
  250. Zhang Y, et al. 2022. J Immunother Cancer. 10:. PubMed
  251. Lee S, et al. 2021. Autophagy. 18:1062. PubMed
  252. Amend A, et al. 2021. Int J Mol Sci. 22:. PubMed
  253. Dai B, et al. 2021. Cell Reports Medicine. 2(8):100381. PubMed
  254. Trivedi S, et al. 2020. Elife. 9:00. PubMed
  255. Hayashi K, et al. 2020. Nat Commun. 4.832638889. PubMed
  256. Fontana C, et al. 2016. J Biol Chem. 291: 7727-7741. PubMed
  257. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
  258. Thomson CA, et al. 2018. J Immunol. 201:215. PubMed
  259. Chen S, et al. 2018. Nat Commun. 9:5298. PubMed
RRID
AB_493568 (BioLegend Cat. No. 117317)
AB_493568 (BioLegend Cat. No. 117318)

Antigen Details

Structure
Integrin α-chain, associates with integrin β2 (CD18), 150 kD
Distribution

Dendritic cells, NK cells, intestinal intraepithelial lymphocytes (IEL), some activated T cells

Function
Cellular adhesion
Ligand/Receptor
iC3b, fibrinogen
Cell Type
Dendritic cells, Epithelial cells, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen Facts Book Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lopez-Rodriguez C, et al. 1996. J. Immunol. 156:3780.

Gene ID
16411 View all products for this Gene ID
UniProt
View information about CD11c on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD11c Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD11c N418 FC
Biotin anti-mouse CD11c N418 FC,IHC-F
FITC anti-mouse CD11c N418 FC
PE anti-mouse CD11c N418 FC
Purified anti-mouse CD11c N418 FC,CyTOF®,IP,IHC
Alexa Fluor® 488 anti-mouse CD11c N418 FC
Alexa Fluor® 647 anti-mouse CD11c N418 FC,IHC,ICC,3D IHC
PE/Cyanine5 anti-mouse CD11c N418 FC
PE/Cyanine7 anti-mouse CD11c N418 FC
Brilliant Violet 605™ anti-mouse CD11c N418 FC
Alexa Fluor® 700 anti-mouse CD11c N418 FC
Pacific Blue™ anti-mouse CD11c N418 FC
APC/Cyanine7 anti-mouse CD11c N418 FC
PerCP/Cyanine5.5 anti-mouse CD11c N418 FC
PerCP anti-mouse CD11c N418 FC
Brilliant Violet 421™ anti-mouse CD11c N418 FC,IHC
Brilliant Violet 570™ anti-mouse CD11c N418 FC
Brilliant Violet 785™ anti-mouse CD11c N418 FC
Brilliant Violet 510™ anti-mouse CD11c N418 FC
Brilliant Violet 650™ anti-mouse CD11c N418 FC
Purified anti-mouse CD11c (Maxpar® Ready) N418 FC,CyTOF®
Alexa Fluor® 594 anti-mouse CD11c N418 IHC-F,3D IHC
PE/Dazzle™ 594 anti-mouse CD11c N418 FC
Brilliant Violet 711™ anti-mouse CD11c N418 FC
APC/Fire™ 750 anti-mouse CD11c N418 FC
TotalSeq™-A0106 anti-mouse CD11c N418 PG
Brilliant Violet 750™ anti-mouse CD11c N418 FC
TotalSeq™-B0106 anti-mouse CD11c N418 PG
TotalSeq™-C0106 anti-mouse CD11c N418 PG
KIRAVIA Blue 520™ anti-mouse CD11c N418 FC
Spark Blue™ 550 anti-mouse CD11c N418 FC
Spark NIR™ 685 anti-mouse CD11c N418 FC
Spark UV™ 387 anti-mouse CD11c N418 FC
Spark Red™ 718 anti-mouse CD11c N418 FC
Spark Blue™ 515 anti-mouse CD11c N418 FC
PerCP/Fire™ 806 anti-mouse CD11c N418 FC
Spark PLUS UV395™ anti-mouse CD11c N418 FC
Spark Blue™ 574 anti-mouse CD11c (Flexi-Fluor™) N418 FC
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account